Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Bengt Kallin"'
Autor:
Bengt Kallin, Per Eriksson, Anders Hamsten, Tiina Skoog, Susanna Boquist, Jan Nilsson, Stefan Jovinge, Ferdinand M. van't Hooft
Publikováno v:
Human Molecular Genetics. 8:1443-1449
Tumour necrosis factor-alpha (TNF-alpha) plays a key role in orchestrating the complex events involved in inflammation and immunity. Accordingly, TNF-alpha has been implicated in a wide range of autoimmune and infectious diseases, but also in conditi
Autor:
Ingemar Björkhem, L. Juntti-Berggren, Mikko P. S. Ares, Johan Thyberg, M. I. Porn-Ares, P.-O. Berggren, Sten Orrenius, Jan Nilsson, Bengt Kallin, Ulf Diczfalusy
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 10, Pp 2049-2061 (1997)
Karolinska Institutet
Europe PubMed Central
Scopus-Elsevier
Karolinska Institutet
Europe PubMed Central
Scopus-Elsevier
We have characterized the death of human aortic smooth muscle cells induced by 25-hydroxycholesterol, an oxidation product of cholesterol. Chromatin condensation characteristic of apoptosis was observed by enzymatic (TUNEL) staining of chromatin, and
Publikováno v:
Cardiovascular Research. 34:418-430
Objectives: After endothelial injury, smooth muscle cells (SMCs) in the arterial media are modified from a contractile to a synthetic phenotype. This process includes a prominent structural reorganization and makes the cells able to migrate into the
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 16:1573-1579
The uptake of oxidatively modified low density lipoprotein (Ox-LDL) by intimal macrophages is believed to play a key role in the development of atherosclerosis. The present study demonstrates that Ox-LDL in low concentrations activates monocyte/macro
Autor:
Per Olof Berggren, M. Isabella Pörn-Ares, Bengt Kallin, Anna Hultgårdh-Nilsson, Jan Nilsson, Mikko P.S. Ares, Sara Moses, Lisa Juntti-Berggren, Johan Thyberg
Publikováno v:
Atherosclerosis. 153(1)
In the present study, we characterize the early cytotoxic effects of 7beta-hydroxycholesterol, a major cytotoxin in oxidized LDL, in human aortic smooth muscle cells. Within a few minutes after addition, 7beta-hydroxycholesterol induced Ca(2+) oscill
Publikováno v:
Karolinska Institutet
Scopus-Elsevier
Scopus-Elsevier
Abstract —Cholesterol-laden, human monocyte–derived macrophages were found to contain 27-hydroxycholesterol in proportion to their content of cholesterol ester. In accordance with previous work with human lung alveolar macrophages, there was a si
Autor:
Milita Crisby, Bengt Kallin, Johan Thyberg, Boris Zhivotovsky, Sten Orrenius, Vasilios Kostulas, Jan Nilsson
Publikováno v:
Vascular Endothelium ISBN: 9781489901354
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b25244900b6e8828bcb86794c0babeb
https://doi.org/10.1007/978-1-4899-0133-0_23
https://doi.org/10.1007/978-1-4899-0133-0_23
Autor:
Johan Thyberg, Bengt Kallin, Jan Nilsson, Milita Crisby, Vasilios Kostulas, Boris Zhivotovsky, Sten Orrenius
Publikováno v:
Atherosclerosis. 130(1-2)
The aim of the present study was to analyze the frequency and mechanism of cell death in atherosclerotic plaques with a recent history ( 70% diameter reduction) undergoing carotid endarterectomy. In situ tailing nick translation of fragmented DNA, ag
Publikováno v:
Differentiation; research in biological diversity. 59(4)
The effects of hexamethylenebisacetamide (HMBA), an inhibitor of poly-ADP-ribosylation, and meta-iodobenzylguanidine (MIBG), an inhibitor of mono-ADP-ribosylation, on the phenotypic properties and proliferation of cultured rat aortic smooth muscle ce
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 15(10)
Abstract Oxidized LDL (Ox-LDL) has been implicated in the development of atherosclerotic lesions, mainly due to its enhanced uptake by macrophages and its ability to alter gene expression in arterial cells. In the present study we demonstrated that O