Výsledky vyhledávání - "Bengt Erik Haug"

Akademický článek

Expression and purification of human neutrophil proteinase 3 from insect cells and characterization of ligand binding.

Autor: Fahimeh Khorsand, Bengt Erik Haug, Inari Kursula, Nathalie Reuter, Ruth Brenk

Publikováno v: PLoS ONE, Vol 19, Iss 6, p e0294827 (2024)

Neutrophil proteinase 3 (PR3) is an important drug target for inflammatory lung diseases such as chronic obstructive pulmonary disease and cystic fibrosis. Drug discovery efforts targeting PR3 require active enzyme for in vitro characterization, such

Externí odkaz: https://doaj.org/article/fc1527840d6345d0bbe0675811fd2772

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Akademický článek

Phospholipid Membrane Interactions of Model Ac-WL-X-LL-OH Peptides Investigated by Solid-State Nuclear Magnetic Resonance

Autor: Nicolai Etwin Alsaker, Øyvind Halskau, Bengt Erik Haug, Nathalie Reuter, Willy Nerdal

Publikováno v: Membranes, Vol 14, Iss 5, p 105 (2024)

The role of aromatic amino acids in peripheral protein membrane binding has been reported to involve cation–π interactions with choline lipids. In this study, we have investigated the interactions of the model pentapeptide Ac-WL-X-LL-OH (where X =

Externí odkaz: https://doaj.org/article/2236dd2f8d6344d8929eb0285c61c6f4

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Akademický článek

Optimized bisubstrate inhibitors for the actin N-terminal acetyltransferase NAA80

Autor: Line M. Myklebust, Markus Baumann, Svein I. Støve, Håvard Foyn, Thomas Arnesen, Bengt Erik Haug

Publikováno v: Frontiers in Chemistry, Vol 11 (2023)

Acetylation of protein N-termini is one of the most common protein modifications in the eukaryotic cell and is catalyzed by the N-terminal acetyltransferase family of enzymes. The N-terminal acetyltransferase NAA80 is expressed in the animal kingdom

Externí odkaz: https://doaj.org/article/867bcc1ac7054fa1916b6b33de2f5ded

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Data from Nitroreductase, a Near-Infrared Reporter Platform for In Vivo Time-Domain Optical Imaging of Metastatic Cancer

Autor: Bjørn Tore Gjertsen, Michael E. Cooper, Bengt Erik Haug, James B. Lorens, David R. Micklem, Tina Pavlin, Richard M. West, Elisabeth Silden, Emmet McCormack

The ability to visualize reporter gene expression in vivo has revolutionized all facets of biologic investigation and none more so than imaging applications in oncology. Near-infrared reporter gene imaging may facilitate more accurate evaluation of c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::491b6ecee1f23c951f45724dbf2aaf8e
https://doi.org/10.1158/0008-5472.c.6505529

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