Zobrazeno 1 - 10
of 908
pro vyhledávání: '"Bengt Glimelius"'
Autor:
Marta Nowak, Faiz Jabbar, Ann-Katrin Rodewald, Luciana Gneo, Tijana Tomasevic, Andrea Harkin, Tim Iveson, Mark Saunders, Rachel Kerr, Karin Oein, Noori Maka, Jennifer Hay, Joanne Edwards, Ian Tomlinson, Owen Sansom, Caroline Kelly, Francesco Pezzella, David Kerr, Alistair Easton, Enric Domingo, Viktor H. Koelzer, David N. Church, Bengt Glimelius, Ismail Gogenur, Emma Jaeger, Hannah Morgan, Clare Orange, Claire Palles, Campbell Roxburgh
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101727- (2024)
Summary: Testing for DNA mismatch repair deficiency (MMRd) is recommended for all colorectal cancers (CRCs). Automating this would enable precision medicine, particularly if providing information on etiology not captured by deep learning (DL) methods
Externí odkaz:
https://doaj.org/article/0addef455aaa46a896ad776bd6ad5c75
Autor:
Bengt Glimelius, Tanweera Khan, Karin Adolfsson, Eva Angenete, Åke Berglund, Kristina Bonde, Nils Elander, Tone Fokstuen, Johan Haux, Israa Imam, Cecilia Lagerbäck, Ingrid Ljuslinder, Andrzej Piwowar, Marie Zajicova, Per J. Nilsson
Publikováno v:
EClinicalMedicine, Vol 75, Iss , Pp 102771- (2024)
Summary: Background: Total neoadjuvant treatment (TNT) for locally advanced rectal cancer (LARC) increases pathologic complete response (pCR) rate and reduces the risk of systemic recurrences over chemoradiotherapy (CRT) in randomised trials, e.g., t
Externí odkaz:
https://doaj.org/article/e883f34623c44a3b9ec58bd2e18a9b0d
Autor:
Bengt Glimelius
Publikováno v:
Upsala Journal of Medical Sciences, Vol 129, Pp 1-13 (2024)
Background: Staging and treatment of rectal cancer have evolved over several decades with considerably fewer locoregional recurrences but no marked improved survival since systemic recurrence risks remain virtually unchanged. This development will br
Externí odkaz:
https://doaj.org/article/2fa8cb6be39e43cca65a66f68082cbe8
Autor:
Sampsa Kinos, Helga Hagman, Päivi Halonen, Leena-Maija Soveri, Mary O'Reilly, Per Pfeiffer, Jan-Erik Frödin, Halfdan Sorbye, Eetu Heervä, Gabor Liposits, Raija Kallio, Annika Ålgars, Raija Ristamäki, Tapio Salminen, Maarit Bärlund, Carl-Henrik Shah, Ray McDermott, Rebecka Röckert, Petra Flygare, Johannes Kwakman, Arco Teske, Cornelis Punt, Bengt Glimelius, Pia Österlund
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background and purpose: The CardioSwitch-study demonstrated that patients with solid tumors who develop cardiotoxicity on capecitabine or 5-fluorouracil (5-FU) treatment can be safely switched to S-1, an alternative fluoropyrimidine (FP). In light of
Externí odkaz:
https://doaj.org/article/340dd2f28c5441ddaf0adaf8e0022afa
Autor:
Ilaria Prata, Martina Eriksson, Jasenko Krdzalic, Elma Meershoek-Klein Kranenbarg, Annet G. H. Roodvoets, Regina Beets-Tan, Cornelis J. H. van de Velde, Boudewijn van Etten, Geke A. P. Hospers, Bengt Glimelius, Per J. Nilsson, Corrie A. M. Marijnen, Koen C. M. J. Peeters, Lennart K. Blomqvist
Publikováno v:
Insights into Imaging, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Background Magnetic resonance (MR) imaging is the modality used for baseline assessment of locally advanced rectal cancer (LARC) and restaging after neoadjuvant treatment. The overall audited quality of MR imaging in large multicentre trials
Externí odkaz:
https://doaj.org/article/5ee9bb25dacb4bb7b809aee0c198cc65
Autor:
Mehrnoosh Shahrivar, Caroline E. Weibull, Karin Ekström Smedby, Bengt Glimelius, Ingvar Syk, Peter Matthiessen, Caroline Nordenvall, Anna Martling
Publikováno v:
Cancer Medicine, Vol 12, Iss 1, Pp 315-324 (2023)
Abstract Background Results from previous studies indicate that use of aspirin may improve colorectal cancer (CRC) survival. The aim of this study was to assess whether use of aspirin influences overall survival or CRC‐specific survival in an unsel
Externí odkaz:
https://doaj.org/article/55d35f0ba0e24b62b6635101111c46e7
Autor:
Malin Ljunggren, Caroline E. Weibull, Emma Rosander, Gabriella Palmer, Bengt Glimelius, Anna Martling, Caroline Nordenvall
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Only a limited proportion of patients with metastatic colorectal cancer (mCRC) receives metastatic surgery (including local ablative therapy). The aim was to investigate whether hospital volume and hospital level were associated w
Externí odkaz:
https://doaj.org/article/727ac0b792af4e2199b0f02d08bd892f
Autor:
Artur Mezheyeuski, Max Backman, Johanna Mattsson, Alfonso Martín-Bernabé, Chatarina Larsson, Ina Hrynchyk, Klara Hammarström, Simon Ström, Joakim Ekström, Siarhei Mauchanski, Salome Khelashvili, Amanda Lindberg, Margrét Agnarsdóttir, Per-Henrik Edqvist, Jutta Huvila, Ulrika Segersten, Per-Uno Malmström, Johan Botling, Björn Nodin, Charlotta Hedner, David Borg, Jenny Brändstedt, Hanna Sartor, Karin Leandersson, Bengt Glimelius, Anna Portyanko, Fredrik Ponten, Karin Jirström, Patrick Micke, Tobias Sjöblom
Publikováno v:
EBioMedicine, Vol 88, Iss , Pp 104452- (2023)
Summary: Background: Cancer immunity is based on the interaction of a multitude of cells in the spatial context of the tumour tissue. Clinically relevant immune signatures are therefore anticipated to fundamentally improve the accuracy in predicting
Externí odkaz:
https://doaj.org/article/21d6bb4dde9a4bcc8ada77b8353d03fb
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 5, Iss 1, Pp 1-27 (2021)
Abstract Background Effective patient-physician communication can improve patient understanding, agreement on treatment and adherence. This may, in turn, impact on clinical outcomes and patient quality of life (QoL). One way to improve communication
Externí odkaz:
https://doaj.org/article/9f2f6767a6ab45a98a45d47a12e717c6
Autor:
Emerik Osterlund, Ari Ristimäki, Soili Kytölä, Teijo Kuopio, Eetu Heervä, Timo Muhonen, Päivi Halonen, Raija Kallio, Leena-Maija Soveri, Jari Sundström, Mauri Keinänen, Annika Ålgars, Raija Ristamäki, Halfdan Sorbye, Per Pfeiffer, Luís Nunes, Tapio Salminen, Annamarja Lamminmäki, Markus J. Mäkinen, Tobias Sjöblom, Helena Isoniemi, Bengt Glimelius, Pia Osterlund
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundKRAS mutations, present in over 40% of metastatic colorectal cancer (mCRC), are negative predictive factors for anti-EGFR therapy. Mutations in KRAS-G12C have a cysteine residue for which drugs have been developed. Published data on this sp
Externí odkaz:
https://doaj.org/article/decb120b6a4a470ea68f4e7d8f7c7d6d