Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Beng Ti Ang"'
Autor:
Yan Zhang, Chi Yan Wong, Carine Z. J. Lim, Qingchang Chen, Zhonglang Yu, Auginia Natalia, Zhigang Wang, Qing You Pang, See Wee Lim, Tze Ping Loh, Beng Ti Ang, Carol Tang, Huilin Shao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Current technologies to subtype glioblastoma (GBM), the most lethal brain tumor, require highly invasive brain biopsies. Here, we develop a dedicated analytical platform to achieve direct and multiplexed profiling of circulating RNAs in extr
Externí odkaz:
https://doaj.org/article/3a2f3d7de2f943d495f2efd2b80e76d0
Autor:
Samantha Ya Lyn Ang, Lester Lee, Angela An Qi See, Ting Yao Ang, Beng Ti Ang, Nicolas Kon Kam King
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Gliomas consist of a heterogeneous group of tumors. This study aimed to report the incidences of O6-methylguanine-DNA-methyltransferase (MGMT) promoter methylation, 1p19q co-deletion, isocitrate dehydrogenase (IDH) gene mutations,
Externí odkaz:
https://doaj.org/article/7ecd7484c5054722b589ac766b32335e
Autor:
Melanie Si Yan Tan, Edwin Sandanaraj, Yuk Kien Chong, See Wee Lim, Lynnette Wei Hsien Koh, Wai Hoe Ng, Nguan Soon Tan, Patrick Tan, Beng Ti Ang, Carol Tang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
STAT3 activates distinct transcriptional programmes within cancer cells. In this study, the authors find that, in glioma, a STAT3-mediated expression signature can stratify patients for targeted precision therapy.
Externí odkaz:
https://doaj.org/article/d61c46f20a3c44179f855b1383771751
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152945 (2016)
Intracerebral hemorrhage (ICH) accounts for 10-15% of all first time strokes and with incidence twice as high in the Asian compared to Western population. This study aims to investigate gender differences in ICH patient outcomes in a multi-ethnic Asi
Externí odkaz:
https://doaj.org/article/f3ac56c0a28044d184354a4c0d68264d
Autor:
Amrapali Zaveri, Jatin Shah, Shreyasee Pradhan, Clarissa Rodrigues, Jacson Barros, Beng Ti Ang, Ricardo Pietrobon
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36759 (2012)
MOTIVATION: Evidence-based medicine (EBM), in the field of neurosurgery, relies on diagnostic studies since Randomized Controlled Trials (RCTs) are uncommon. However, diagnostic study reporting is less standardized which increases the difficulty in r
Externí odkaz:
https://doaj.org/article/1c4896fbbafa482dafcae1f47bc41ba9
Publikováno v:
Pathology. 55:432-435
Autor:
Beng Ti Ang, Carol Tang, Ivan Ng, Wai Hoe Ng, Greg Tucker-Kellogg, Oi Lian Kon, Siew Hong Leong, Swee Seong Wong, Mark Phong, Edwin Sandanaraj, Geraldene Rong-Hui Koh, Esther Hui-Ling Ting, Tan Boon Toh, Felicia Soo-Lee Ng
PDF file - 688K, Supplementary Fig. S1. NNI-8 GPCs display stemness expression and extensive self-renewal.Supplementary Fig. S2. NNI-8 orthotopic xenograft recapitulates patient tumor pathophysiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703b30891d9d2694cbe9d4c67ee4df2d
https://doi.org/10.1158/1078-0432.22443275.v1
https://doi.org/10.1158/1078-0432.22443275.v1
Autor:
Beng Ti Ang, Carol Tang, Ivan Ng, Wai Hoe Ng, Greg Tucker-Kellogg, Oi Lian Kon, Siew Hong Leong, Swee Seong Wong, Mark Phong, Edwin Sandanaraj, Geraldene Rong-Hui Koh, Esther Hui-Ling Ting, Tan Boon Toh, Felicia Soo-Lee Ng
Purpose: Patient-derived glioma-propagating cells (GPC) contain karyotypic and gene expression profiles that are found in the primary tumor. However, their clinical relevance is unclear. We ask whether GPCs contribute to disease progression and survi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a37b35ff8e93d27a56a4853cc92c65ad
https://doi.org/10.1158/1078-0432.c.6519749
https://doi.org/10.1158/1078-0432.c.6519749
Autor:
Kah-Leong Lim, Carol Tang, Ryosuke Takahashi, Beng-Ti Ang, Joanna D. Holbrook, Edwin Sandanaraj, Charlene S.F. Foong, Lynnette W.H. Koh, Yuk Kien Chong, Geraldene R.H. Koh, Jeanne M.M. Tan, Chou Chai, Felicia S.L. Ng, Calvin W.S. Yeo
Mutations in the parkin gene, which encodes a ubiquitin ligase, are a major genetic cause of parkinsonism. Interestingly, parkin also plays a role in cancer as a putative tumor suppressor, and the gene is frequently targeted by deletion and inactivat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abb9f03b215b799e214de69512817fed
https://doi.org/10.1158/0008-5472.c.6502959.v1
https://doi.org/10.1158/0008-5472.c.6502959.v1
Autor:
Kah-Leong Lim, Carol Tang, Ryosuke Takahashi, Beng-Ti Ang, Joanna D. Holbrook, Edwin Sandanaraj, Charlene S.F. Foong, Lynnette W.H. Koh, Yuk Kien Chong, Geraldene R.H. Koh, Jeanne M.M. Tan, Chou Chai, Felicia S.L. Ng, Calvin W.S. Yeo
PDF file - 64K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe96a3645ea7acb872fd18ed47676d7
https://doi.org/10.1158/0008-5472.22390458
https://doi.org/10.1158/0008-5472.22390458