The nuclear factor ID3 endows macrophages with a potent anti-tumour activity.

Autor: Deng Z; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Loyher PL; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lazarov T; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Graduate School of Medical Sciences, New York, NY, USA., Li L; Graduate Center, City University of New York, New York, NY, USA., Shen Z; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA., Bhinder B; Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell, New York, NY, USA., Yang H; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Zhong Y; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Alberdi A; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Massague J; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Sun JC; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Benezra R; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Glass CK; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA., Elemento O; Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell, New York, NY, USA., Iacobuzio-Donahue CA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Geissmann F; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. geissmaf@mskcc.org.; Weill Cornell Graduate School of Medical Sciences, New York, NY, USA. geissmaf@mskcc.org.

Publikováno v: Nature [Nature] 2024 Feb; Vol. 626 (8000), pp. 864-873. Date of Electronic Publication: 2024 Feb 07.

Retraction: Id1 Deficiency Protects Against Tumor Formation in ApcMin/+ Mice but not in a Mouse Model of Colitis-associated Colon Cancer.

Autor: Zhang N, Subbaramaiah K, Yantiss RK, Zhou XK, Chin Y, Benezra R, Dannenberg AJ

Publikováno v: Cancer prevention research (Philadelphia, Pa.) [Cancer Prev Res (Phila)] 2022 Jun 02; Vol. 15 (6), pp. 407.

Anti-tumor effects of an ID antagonist with no observed acquired resistance.

Autor: Wojnarowicz PM; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Escolano MG; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Huang YH; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell/Sloan Kettering/Rockefeller Tri-Institutional MD-PhD Program, New York, NY, 10065, USA.; Gerstner Sloan Kettering Graduate School of Biomedical Sciences, New York, NY, 10065, USA., Desai B; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chin Y; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Shah R; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Xu S; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Yadav S; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Yaklichkin S; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ouerfelli O; Organic Synthesis Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Soni RK; Proteomics & Microchemistry Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Philip J; Proteomics & Microchemistry Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Montrose DC; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.; Department of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA., Healey JH; Orthopedics Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rajasekhar VK; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Garland WA; Tosk, Inc., Mountain View, CA, USA., Ratiu J; Department of Immunology, Duke University, Durham, NC, USA., Zhuang Y; Department of Immunology, Duke University, Durham, NC, USA., Norton L; Evelyn H. Lauder Breast Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rosen N; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hendrickson RC; Proteomics & Microchemistry Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Zhou XK; Department of Healthcare Policy and Research Weill Cornell Medical College, New York, NY, USA., Iavarone A; Department of Neurology, Department of Pathology, Institute for Cancer Genetics, Columbia University Medical Center, New York, NY, USA., Massague J; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Dannenberg AJ; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Lasorella A; Department of Pediatrics, Department of Pathology, Institute for Cancer Genetics, Columbia University Medical Center, New York, NY, USA., Benezra R; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. benezrar@mskcc.org.

Publikováno v: NPJ breast cancer [NPJ Breast Cancer] 2021 May 24; Vol. 7 (1), pp. 58. Date of Electronic Publication: 2021 May 24.

TRIP13: A promising cancer immunotherapy target.

Autor: Jing, Shengnan¹ (AUTHOR), Zhao, Liya¹ (AUTHOR), Zhao, Liwen¹ (AUTHOR), Gao, Yong‐Jing¹ (AUTHOR) gaoyongjing@ntu.edu.cn, He, Tianzhen¹ (AUTHOR) sailing198562@ntu.edu.cn

Publikováno v: Cancer Innovation. Dec2024, Vol. 3 Issue 6, p1-10. 10p.

ALDH1A3 Contributes to Radiation-Induced Inhibition of Self-Renewal and Promotes Proliferative Activity of p53-Deficient Glioblastoma Stem Cells at the Onset of Differentiation.

Autor: Müller, Andreas¹ (AUTHOR) mandre@students.uni-mainz.de, Lyubarskyy, Bogdan¹ (AUTHOR), Tchoumakov, Jurij¹ (AUTHOR), Wagner, Maike¹ (AUTHOR), Sprang, Bettina¹ (AUTHOR), Ringel, Florian¹ (AUTHOR), Kim, Ella L.¹ (AUTHOR) ella.kim@unimedizin-mainz.de

Publikováno v: Cells (2073-4409). Nov2024, Vol. 13 Issue 21, p1802. 18p.