Výsledky vyhledávání

Therapeutic Strategies Targeting Mitochondrial Calcium Signaling: A New Hope for Neurological Diseases?

Autor: Rodriguez L, Lapena-Luzon T, Beneto N, Beltran-Beltran V, Pallardo F, Gonzalez-Cabo P, Navarro J

Publikováno v: ANTIOXIDANTS
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname

Calcium (Ca2+) is a versatile secondary messenger involved in the regulation of a plethora of different signaling pathways for cell maintenance. Specifically, intracellular Ca2+ homeostasis is mainly regulated by the endoplasmic reticulum and the mit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::579f206893c6f3276d1f2e6e59bed230
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=16398

Zobrazit plný text záznamu

Genome Editing Using Cas9-gRNA Ribonucleoprotein in Human Pluripotent Stem Cells for Disease Modeling

Autor: Beneto N, Grinberg-Vaisman DR, Vilageliu L, Canals I

Publikováno v: Methods In Molecular Biology (clifton, N.J.)
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

The discovery that the CRISPR/Cas9 system could be used for genome editing purposes represented a major breakthrough in the field. This advancement has notably facilitated the introduction or correction of disease-specific mutations in healthy or dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b10006c305f74e364ee60bee3c9ae9c4
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=19321

Zobrazit plný text záznamu

Cofilin and Neurodegeneration: New Functions for an Old but Gold Protein

Autor: Lapena-Luzon T, Rodriguez L, Beltran-Beltran V, Beneto N, Pallardo F, Gonzalez-Cabo P

Publikováno v: Brain Sciences
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname

Cofilin is an actin-binding protein that plays a major role in the regulation of actin dynamics, an essential cellular process. This protein has emerged as a crucial molecule for functions of the nervous system including motility and guidance of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::72579195a366ddda66b6805c6b66bd5c
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15837

Zobrazit plný text záznamu

Role of Adenosine Receptors in Rare Neurodegenerative Diseases with Motor Symptoms

Autor: Beltran-Beltran V, Beneto N, Lapena-Luzon T, Rodriguez L, Pallardo F, Gonzalez-Cabo P

Publikováno v: Current Protein & Peptide Science
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname

The approval of istradefylline, an adenosine 2A receptor (A2AR) antagonist, as an add-on treatment in adult patients with Parkinson's disease by the Food and Drug Administration (FDA) and European Medicines Agency (EMA), is the latest proof of the im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::1e427953fc6f9d4c7079d106ff8c05d8
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15988

Zobrazit plný text záznamu

Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndrome

Autor: Beneto N, Cozar M, Gort L, Pacheco L, Vilageliu L, Grinberg-Vaisman DR, Canals I

Publikováno v: STEM CELL RESEARCH
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4b7ebbc95c4c4d74c39f0ed1117a5247
https://reader.elsevier.com/reader/sd/pii/S1873506119302983?token=74ACD0EBA8707A5F6AB11A8A7667B3F079A653E6BB46F2D899FE81CAE8EECE28A3DB81BFACAAB67AE1F590FCC4DA00B9&originRegion=eu-west-1&originCreation=20210722082134

Zobrazit plný text záznamu

DDC expression is not regulated by NFAT5 (TonEBP) in dopaminergic neural cell lines

Autor: Pineda L, Cabana J, Beneto N, Diez H, Arenas C, Cormand B, Fernandez N

Publikováno v: Gene
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

The nuclear factor of activated T-cells 5 (NFAT5), also known as tonicity-responsive enhancer-binding protein (TonEBP), is a transcription factor that regulates osmoadaptive response in multiple tissues and is highly expressed in the developing centr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6e7303d3622755350d96dc6afbf540dc
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=17531

Zobrazit plný text záznamu

Neuronal and Astrocytic Differentiation from Sanfilippo C Syndrome iPSCs for Disease Modeling and Drug Development

Autor: Beneto N, Cozar M, Castilla-Vallmanya L, Zetterdahl OG, Sacultanu M, Segur-Bailach E, García-Morant M, Ribes A, Ahlenius H, Grinberg-Vaisman DR, Vilageliu L, Canals I

Publikováno v: Journal of Clinical Medicine
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname

Sanfilippo syndrome type C (mucopolysaccharidosis IIIC) is an early-onset neurodegenerative lysosomal storage disorder, which is currently untreatable. The vast majority of studies focusing on disease mechanisms of Sanfilippo syndrome were performed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2b465c148da7901c81e0d2ce513c1a90
https://www.mdpi.com/2077-0383/9/3/644

Zobrazit plný text záznamu

Sanfilippo Syndrome: Molecular Basis, Disease Models and Therapeutic Approaches

Autor: Beneto N, Vilageliu L, Grinberg-Vaisman DR, Canals I

Publikováno v: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

Sanfilippo syndrome or mucopolysaccharidosis III is a lysosomal storage disorder caused by mutations in genes responsible for the degradation of heparan sulfate, a glycosaminoglycan located in the extracellular membrane. Undegraded heparan sulfate mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ced9f03bc4b22accbf3e3ab48f082100
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=18370

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání