Sustained hypoxia in mice increases parasympathetic but not sympathetic tone

Autor: Juliana R. Souza, Mauro de Oliveira, Benedito H. Machado

Publikováno v: Current Research in Physiology, Vol 5, Iss , Pp 361-368 (2022)

The autonomic profile of mice submitted to sustained hypoxia (SH) was not yet fully evaluated. Herein, we characterized the cardiovascular and autonomic profile of conscious freely moving mice submitted to SH using two sequential experimental protoco

Externí odkaz: https://doaj.org/article/86c81838293347b68f010ff59283bf5a

Contributors

Autor: Daniela Accorsi–Mendonça, David J. Adams, Andrew M. Allen, Marlies Alvarenga, Jeffrey L. Ardell, Amy C. Arnold, Jesse L. Ashton, Mark B. Badrov, Brennan A. Ballantyne, Emma N. Bardsley, Soledad Barez-Lopez, Susan M. Barman, Carolyn J. Barrett, Deborah Bauer, Christopher Bell, Alona Ben-Tal, Eduardo E. Benarroch, Italo Biaggioni, Katharina Brandl, Virginia L. Brooks, Amy E. Brown, Kirsteen N. Browning, Meredith Bryarly, Livia L. Camargo, Michael Camilleri, Preston J. Campbell, Marc G. Caron, Jason R. Carter, Mark W. Chapleau, Nisha Charkoudian, Gisela Chelimsky, Thomas C. Chelimsky, Pitcha Chompoopong, Victoria E. Claydon, Gilles Clément, Victor A. Convertino, Elizabeth A. Coon, Pietro Cortelli, Stephen N. Davis, André Diedrich, Donald J. DiPette, Debra I. Diz, Marcus J. Drake, Graeme Eisenhofer, Florent Elefteriou, Fernando Elijovich, Eva-Maria Elmenhorst, Brett A. English, Murray Esler, Rosemary Esler, Paul J. Fadel, John M. Fahrenholz, Alessandra Fanciulli, John Y. Fang, Robert D. Fealey, Nathanne S. Ferreira, Renato Filogonio, Gregory D. Fink, James P. Fisher, John S. Floras, Samuel J. Fountain, Qi Fu, Marat Fudim, Raffaello Furlan, Alfredo Gamboa, Emily M. Garland, Christopher H. Gibbons, Andrew Giritharan, David S. Goldstein, Diego A. Golombék, Elise P. Gomez-Sanchez, Celso E. Gomez-Sanchez, Robert M. Graham, Guido Grassi, Ian M. Greenlund, Blair P. Grubb, Alla Guekht, Sarah-Jane Guild, Ling Guo, Vsevolod V. Gurevich, Ralf Habermann, Joseph Hadaya, Maureen K. Hahn, Peter Hanna, Luke A. Henderson, Neil Herring, Max J. Hilz, Peter Hunter, Keith Hyland, Lauren A. Hyland, Edwin Kerry Jackson, Giris Jacob, Wilfrid Jänig, Nina Japundžić-Žigon, Carrie K. Jones, Karen M. Joos, Jens Jordan, William Joyce, Xenia Kaidonis, Horacio Kaufmann, David Kaye, Abdul Mannan Khan Minhas, Joyce S. Kim, Takeya Kitta, David D. Kline, Thomas Konecny, Natalie J. Koons, Ambrish Kumar, Cheryl L. Laffer, Andre H. Lagrange, Nora Laiken, Gavin Lambert, Elisabeth Lambert, Guillaume Lamotte, Jacques W.M. Lenders, Benjamin D. Levine, Fabian Leys, Ulrich Limper, Mabelle Lin, Eduardo Listik, Reid Longmuir, David A. Low, Phillip A. Low, James M. Luther, Vaughan G. Macefield, Benedito H. Machado, Maria-Bernadette Madel, Davide Martelli, Christopher J. Mathias, Michelle L. Mauermann, Robin M. McAllen, Fiona D. McBryde, Andrew McKeon, Michael J. McKinley, Clément Menuet, Douglas F. Milam, Marion C. Mohl, Johanna M. Montgomery, Davi J.A. Moraes, Shaun F. Morrison, David Murphy, Charles D. Nichols, Piotr Niewiński, Lucy Norcliffe-Kaufmann, Luis E. Okamoto, Mahyar Osanlouy, John W. Osborn, Viktor Oubaid, Jose-Alberto Palma, Christina Pamporaki, Brian A. Parsons, David J. Paterson, Julian F.R. Paton, Amanda C. Peltier, Umberto Pensato, Sean M. Peterson, Fenna T. Phibbs, Giulia Pierangeli, Jay D. Potts, Alejandro A. Rabinstein, Mohan K. Raizada, Satish R. Raj, Casey M. Rand, Heinz Reichmann, Calum Robertson, Rose Marie Robertson, Michael B. Robinson, Mohammed Ruzieh, Paola Sandroni, Takayuki Sato, Ernesto L. Schiffrin, Markus Schlaich, Ronald Schondorf, Harold D. Schultz, Michael M. Scott, Gino Seravalle, John R. Shannon, Abu Baker Sheikh, Cyndya A. Shibao, Kalyanam Shivkumar, Kamal Shouman, Timo Siepmann, Wolfgang Singer, Elias Soltani, Virend Somers, Aadhavi Sridharan, Nadia Stefanova, Julian Stewart, Lauren E. Stiles, Kenji Sunagawa, Jens Tank, Roland D. Thijs, Jakub Tomek, Rhian M. Touyz, Jennifer A. Tracy, R. Alberto Travagli, Bradley J. Undem, Nikhil Urs, Steven Vernino, Lauro C. Vianna, Daniel E. Vigo, Margaret A. Vizzard, Amr Wahba, Waqar Waheed, Han-Jun Wang, Tobias Wang, Qin Wang, Ruihao Wang, Debra E. Weese-Mayer, Gregor K. Wenning, Wouter Wieling, Kevin W. Williams, Ursula H. Winzer-Serhan, Scott Wood, Kai Lee Yap, Naoki Yoshimura, Kirill A. Zavalin, Dmitry Zhuravlev, Daniel B. Zoccal, Jasenka Zubcevic

Publikováno v: Primer on the Autonomic Nervous System ISBN: 9780323854924

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6bafd1601fa1262b19bc5727a98b1d87
https://doi.org/10.1016/b978-0-323-85492-4.01002-4

Intrinsic and synaptic mechanisms controlling the expiratory activity of excitatory lateral parafacial neurones of rats

Autor: Melina P. da Silva, Davi J. A. Moraes, André S. Mecawi, Benedito H. Machado, Julian F. R. Paton, Karolyne S. Magalhães

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Active expiration is essential for increasing pulmonary ventilation during high chemical drive (hypercapnia). The lateral parafacial (pFL ) region, which contains expiratory neurones, drives abdominal muscles during active expiration in response to h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba91c784eebfd4d30df4fa4ab6682f4
https://doi.org/10.1113/jp281545

PACEMAKING PROPERTY OF RVLM PRESYMPATHETIC NEURONS

Autor: Daniela Accorsi-Mendonça, Melina P da Silva, George MPR Souza, Ludmila L Silveira, Marlusa Karlen-Amarante, Mateus R Amorim, Carlos EL Almado, Davi JA Moraes, Benedito H Machado

Publikováno v: Frontiers in Physiology, Vol 7 (2016)

Despite several studies describing the electrophysiological properties of RVLM presympathetic neurons, there is no consensus in the literature about their pacemaking property, mainly due to different experimental approaches used for recordings of neu

Externí odkaz: https://doaj.org/article/169381b92d2b48a1b375480b99529873

Centrally acting adrenomedullin in the long‐term potentiation of sympathetic vasoconstrictor activity induced by intermittent hypoxia in rats

Autor: Daniel B. Zoccal, Melina P. da Silva, Davi J. A. Moraes, Karine C. Flor, David Murphy, Debora S. A. Colombari, Eduardo Colombari, Julian F. R. Paton, Benedito H. Machado, João Henrique Costa-Silva

Publikováno v: Zoccal, D B, Colombari, D S A, Colombari, E, Flor, K C, da Silva, M P, Costa-Silva, J H, Machado, B H, Moraes, D J A, Murphy, D & Paton, J F R 2019, ' Centrally acting adrenomedullin in the long-term potentiation of sympathetic vasoconstrictor activity induced by intermittent hypoxia in rats ', Experimental Physiology, vol. 104, no. 9, pp. 1371-1383 . https://doi.org/10.1113/EP087613
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

NEW FINDINGS What is the central question of this study? Adrenomedullin in the rostral ventrolateral medulla (RVLM) increases sympathetic activity; given that adrenomedullin is released during hypoxia, what are the effects of its agonism and antagoni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5899f5c9118c3023b68708670b05ecf6
https://doi.org/10.1113/ep087613