Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Benedikt Westermann"'
Autor:
Xenia Chelius, Veronika Bartosch, Nathalie Rausch, Magdalena Haubner, Jana Schramm, Ralf J Braun, Till Klecker, Benedikt Westermann
Publikováno v:
PLoS Biology, Vol 21, Iss 9, p e3002310 (2023)
Decline of mitochondrial function is a hallmark of cellular aging. To counteract this process, some cells inherit mitochondria asymmetrically to rejuvenate daughter cells. The molecular mechanisms that control this process are poorly understood. Here
Externí odkaz:
https://doaj.org/article/86e2fcd1831a4778a854fa007e26b7d5
Autor:
Anna Lechado-Terradas, Sandra Schepers, Katharina I. Zittlau, Karan Sharma, Orkun Ok, Julia C. Fitzgerald, Stefan Geimer, Benedikt Westermann, Boris Macek, Philipp J. Kahle
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 576-602 (2022)
PINK1/parkin-dependent mitophagy initially involves (phospho)ubiquitin-directed proteasome-dependent degradation of certain outer mitochondrial membrane (OMM) proteins (e.g. mitofusins) and the recruitment of autophagy adaptors to a group of ubiquiti
Externí odkaz:
https://doaj.org/article/28921611ba294240a516a15b1a04f119
Autor:
Till Klecker, Benedikt Westermann
Publikováno v:
Open Biology, Vol 11, Iss 12 (2021)
Mitochondria are complex organelles with two membranes. Their architecture is determined by characteristic folds of the inner membrane, termed cristae. Recent studies in yeast and other organisms led to the identification of four major pathways that
Externí odkaz:
https://doaj.org/article/75ecfe2df5b849dc9bd84ff4db1fee07
Publikováno v:
Microbial Cell, Vol 7, Iss 9, Pp 234-249 (2020)
The production of metabolic energy in form of ATP by oxidative phosphorylation depends on the coordinated action of hundreds of nuclear-encoded mitochondrial proteins and a handful of proteins encoded by the mitochondrial genome (mtDNA). We used the
Externí odkaz:
https://doaj.org/article/d1dee1ef25ed49b3bbac0ad1e68f631e
Publikováno v:
Microbial Cell, Vol 5, Iss 4, Pp 198-207 (2018)
In aerobic organisms, mitochondrial F1Fo-ATP-synthase is the major site of ATP production. Beside this fundamental role, the protein complex is involved in shaping and maintenance of cristae. Previous electron microscopic studies identified the disso
Externí odkaz:
https://doaj.org/article/cb1bd9a91ee747db9a872edc60d0d649
Autor:
Didac Carmona-Gutierrez, Maria Anna Bauer, Andreas Zimmermann, Andrés Aguilera, Nicanor Austriaco, Kathryn Ayscough, Rena Balzan, Shoshana Bar-Nun, Antonio Barrientos, Peter Belenky, Marc Blondel, Ralf J. Braun, Michael Breitenbach, William C. Burhans, Sabrina Büttner, Duccio Cavalieri, Michael Chang, Katrina F. Cooper, Manuela Côrte-Real, Vítor Costa, Christophe Cullin, Ian Dawes, Jörn Dengjel, Martin B. Dickman, Tobias Eisenberg, Birthe Fahrenkrog, Nicolas Fasel, Kai-Uwe Fröhlich, Ali Gargouri, Sergio Giannattasio, Paola Goffrini, Campbell W. Gourlay, Chris M. Grant, Michael T. Greenwood, Nicoletta Guaragnella, Thomas Heger, Jürgen Heinisch, Eva Herker, Johannes M. Herrmann, Sebastian Hofer, Antonio Jiménez-Ruiz, Helmut Jungwirth, Katharina Kainz, Dimitrios P. Kontoyiannis, Paula Ludovico, Stéphen Manon, Enzo Martegani, Cristina Mazzoni, Lynn A. Megeney, Chris Meisinger, Jens Nielsen, Thomas Nyström, Heinz D. Osiewacz, Tiago F. Outeiro, Hay-Oak Park, Tobias Pendl, Dina Petranovic, Stephane Picot, Peter Polčic, Mark Ramsdale, Mark Rinnerthaler, Patrick Rockenfeller, Christoph Ruckenstuhl, Raffael Schaffrath, Maria Segovia, Fedor F. Severin, Amir Sharon, Stephan J. Sigrist, Cornelia Sommer-Ruck, Maria João Sousa, Johan M. Thevelein, Karin Thevissen, Vladimir Titorenko, Michel B. Toledano, Mick Tuite, F.-Nora Vögtle, Benedikt Westermann, Joris Winderickx, Silke Wissing, Stefan Wölfl, Zhaojie J. Zhang, Richard Y. Zhao, Bing Zhou, Lorenzo Galluzzi, Guido Kroemer, Frank Madeo
Publikováno v:
Microbial Cell, Vol 5, Iss 1, Pp 4-31 (2018)
Elucidating the biology of yeast in its full complexity has major implications for science, medicine and industry. One of the most critical processes determining yeast life and physiology is cellular demise. However, the investigation of yeast cell d
Externí odkaz:
https://doaj.org/article/7204719614c446e08c16d57347cd80b5
Autor:
Max E Harner, Ann-Katrin Unger, Willie JC Geerts, Muriel Mari, Toshiaki Izawa, Maria Stenger, Stefan Geimer, Fulvio Reggiori, Benedikt Westermann, Walter Neupert
Publikováno v:
eLife, Vol 5 (2016)
Metabolic function and architecture of mitochondria are intimately linked. More than 60 years ago, cristae were discovered as characteristic elements of mitochondria that harbor the protein complexes of oxidative phosphorylation, but how cristae are
Externí odkaz:
https://doaj.org/article/e8461339cad64b2fb5a7ee4a41d66d0f
Autor:
Max Emanuel Harner, Ann-Katrin Unger, Toshiaki Izawa, Dirk M Walther, Cagakan Özbalci, Stefan Geimer, Fulvio Reggiori, Britta Brügger, Matthias Mann, Benedikt Westermann, Walter Neupert
Publikováno v:
eLife, Vol 3 (2014)
Structure and function of mitochondria are intimately linked. In a search for components that participate in building the elaborate architecture of this complex organelle we have identified Aim24, an inner membrane protein. Aim24 interacts with the M
Externí odkaz:
https://doaj.org/article/b385792a066c4cf49bffc087f665a318
Autor:
Eric Hummel, Peter Guttmann, Stephan Werner, Basel Tarek, Gerd Schneider, Michael Kunz, Achilleas S Frangakis, Benedikt Westermann
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53293 (2012)
The complex architecture of their structural elements and compartments is a hallmark of eukaryotic cells. The creation of high resolution models of whole cells has been limited by the relatively low resolution of conventional light microscopes and th
Externí odkaz:
https://doaj.org/article/fa6a753a08a44f5590e477647aa710e3
Autor:
Siavash Khosravi, Xenia Chelius, Ann-Katrin Unger, Daniela Rieger, Johanna Frickel, Timo Sachsenheimer, Christian Lüchtenborg, Rico Schieweck, Britta Brügger, Benedikt Westermann, Till Klecker, Walter Neupert, Max E. Harner
Publikováno v:
Journal of Cell Science. 136
Mitochondria are essential organelles of eukaryotic cells and are characterized by their unique and complex membrane system. They are confined from the cytosol by an envelope consisting of two membranes. Signals, metabolites, proteins and lipids have