Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Benedikt Simbrunner"'
Autor:
Oleksandr Petrenko, Philipp Königshofer, Ksenia Brusilovskaya, Benedikt S. Hofer, Katharina Bareiner, Benedikt Simbrunner, Frank Jühling, Thomas F. Baumert, Joachim Lupberger, Michael Trauner, Stefan G. Kauschke, Larissa Pfisterer, Eric Simon, André F. Rendeiro, Laura P.M.H. de Rooij, Philipp Schwabl, Thomas Reiberger
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109301- (2024)
Summary: Persistent liver injury triggers a fibrogenic program that causes pathologic remodeling of the hepatic microenvironment (i.e., liver fibrosis) and portal hypertension. The dynamics of gene regulation during liver disease progression and earl
Externí odkaz:
https://doaj.org/article/86925cb6106c40e38d57b9872bca512c
Autor:
Lukas Hartl, Benedikt Simbrunner, Mathias Jachs, Peter Wolf, David Josef Maria Bauer, Bernhard Scheiner, Lorenz Balcar, Georg Semmler, Michael Schwarz, Rodrig Marculescu, Varius Dannenberg, Michael Trauner, Mattias Mandorfer, Thomas Reiberger
Publikováno v:
JHEP Reports, Vol 6, Iss 1, Pp 100954- (2024)
Background & Aims: Advanced chronic liver disease (ACLD) may affect thyroid hormone homeostasis. We aimed to analyze the pituitary–thyroid axis in ACLD and the prognostic value of free triiodothyronine (fT3). Methods: Patients with ACLD (liver stif
Externí odkaz:
https://doaj.org/article/6a8f9cd0fcc44a62a0377cde70db88a7
Autor:
Lorenz Balcar, Benedikt Simbrunner, Rafael Paternostro, Mathias Jachs, Lukas Hartl, Georg Semmler, Benedikt Silvester Hofer, Albert Friedrich Stättermayer, Matthias Pinter, Ton Lisman, Michael Trauner, Peter Quehenberger, Thomas Reiberger, Bernhard Scheiner, Mattias Mandorfer
Publikováno v:
JHEP Reports, Vol 6, Iss 1, Pp 100934- (2024)
Background & Aims: Increased aggregation of individual platelets upon activation, as assessed by whole blood aggregometry standardised to platelet count (PLT), has recently been linked to progression of advanced chronic liver disease (ACLD). Moreover
Externí odkaz:
https://doaj.org/article/5cd4738087fd49dda7f345254ce5ce13
Autor:
Lukas Hartl, Benedikt Rumpf, Oliver Domenig, Benedikt Simbrunner, Rafael Paternostro, Mathias Jachs, Marko Poglitsch, Rodrig Marculescu, Michael Trauner, Roman Reindl-Schwaighofer, Manfred Hecking, Mattias Mandorfer, Thomas Reiberger
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract We aimed to assess the systemic and hepatic renin-angiotensin-system (RAS) fingerprint in advanced chronic liver disease (ACLD). This prospective study included 13 compensated (cACLD) and 12 decompensated ACLD (dACLD) patients undergoing hep
Externí odkaz:
https://doaj.org/article/1135ed85629041d8bc558fb1e8dafc54
Autor:
Lukas Hartl, Benedikt Simbrunner, Mathias Jachs, Peter Wolf, David Josef Maria Bauer, Bernhard Scheiner, Lorenz Balcar, Georg Semmler, Michael Schwarz, Rodrig Marculescu, Michael Trauner, Mattias Mandorfer, Thomas Reiberger
Publikováno v:
JHEP Reports, Vol 5, Iss 8, Pp 100789- (2023)
Background & Aims: Inadequate adrenal function has been described in patients with cirrhosis. We investigated (i) the pituitary–adrenal axis at different clinical stages and (ii) the clinical impact of decreased serum cortisol levels in stable pati
Externí odkaz:
https://doaj.org/article/2f12038ca58a4e0cad4ea8d2504adbea
Autor:
Benedikt S. Hofer, Benedikt Simbrunner, David J. M. Bauer, Rafael Paternostro, Philipp Schwabl, Bernhard Scheiner, Georg Semmler, Lukas Hartl, Mathias Jachs, Barbara Datterl, Albert F. Staettermayer, Michael Trauner, Mattias Mandorfer, Thomas Reiberger
Publikováno v:
Hepatology Communications, Vol 6, Iss 9, Pp 2569-2580 (2022)
Abstract Nonselective beta‐blockers are used as prophylaxis for variceal bleeding in patients with advanced chronic liver disease (ACLD). The acute hemodynamic response to intravenous propranolol (i.e., ≥10% reduction in hepatic venous pressure g
Externí odkaz:
https://doaj.org/article/8872b398c23a4c5d9378a84b5a9c5055
Autor:
Ksenia Brusilovskaya, Benedikt Simbrunner, Silvia Lee, Beate Eichelberger, David Bauer, Kerstin Zinober, Philipp Schwabl, Mattias Mandorfer, Simon Panzer, Thomas Reiberger, Thomas Gremmel
Publikováno v:
Platelets, Vol 33, Iss 6, Pp 879-886 (2022)
Cirrhotic patients have an increased risk of bleeding and thromboembolic events, with platelets being involved as key players in both situations. The impact of peripheral versus central blood sampling on platelet activation remains unclear. In 33 cir
Externí odkaz:
https://doaj.org/article/7b951a4cfbbf4007b196cae5bdd76720
Autor:
Benedikt Simbrunner, Lukas Hartl, Mathias Jachs, David J.M. Bauer, Bernhard Scheiner, Benedikt Silvester Hofer, Albert Friedrich Stättermayer, Rodrig Marculescu, Michael Trauner, Mattias Mandorfer, Thomas Reiberger
Publikováno v:
JHEP Reports, Vol 5, Iss 5, Pp 100712- (2023)
Background & Aims: Cirrhosis-associated immune dysfunction (CAID) affects both innate and adaptive immunity. This study investigated the complement system, immunoglobulins, and acute-phase proteins and their prognostic relevance in patients with adva
Externí odkaz:
https://doaj.org/article/39f5d0d33ac542cf99205e0557f2b4a5
Autor:
Lorenz Balcar, Julia Krawanja, Bernhard Scheiner, Rafael Paternostro, Benedikt Simbrunner, Georg Semmler, Mathias Jachs, Lukas Hartl, Albert Friedrich Stättermayer, Philipp Schwabl, Matthias Pinter, Thomas Szekeres, Michael Trauner, Thomas Reiberger, Mattias Mandorfer
Publikováno v:
JHEP Reports, Vol 5, Iss 4, Pp 100682- (2023)
Background & Aims: Ammonia levels predicted hospitalisation in a recent landmark study not accounting for portal hypertension and systemic inflammation severity. We investigated (i) the prognostic value of venous ammonia levels (outcome cohort) for l
Externí odkaz:
https://doaj.org/article/b19f2478a3fd41be925cb5cd0689552f
Autor:
Lukas Hartl, Georg Semmler, Benedikt Silvester Hofer, Nawa Schirwani, Mathias Jachs, Benedikt Simbrunner, David Josef Maria Bauer, Teresa Binter, Katharina Pomej, Matthias Pinter, Michael Trauner, Mattias Mandorfer, Thomas Reiberger, Bernhard Scheiner
Publikováno v:
Hepatology Communications, Vol 5, Iss 10, Pp 1660-1675 (2021)
The coronavirus disease 2019 (COVID‐19) pandemic necessitated down‐scaling of in‐hospital care to prohibit the spread of severe acute respiratory syndrome–coronavirus‐2. We (1) assessed patient perceptions on quality of care by telesurvey (
Externí odkaz:
https://doaj.org/article/8ef7d2f2fb9e47a19bf8536a0e916f35