Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Benedikt Mothes"'
1
Akademický článek
Deficiency of PI3-Kinase catalytic isoforms p110γ and p110δ in mice enhances the IL-17/G-CSF axis and induces neutrophilia
Autor: Kirsten Bucher, Fee Schmitt, Benedikt Mothes, Carolin Blumendeller, Daniel Schäll, Roland Piekorz, Emilio Hirsch, Bernd Nürnberg, Sandra Beer-Hammer
Publikováno v: Cell Communication and Signaling, Vol 15, Iss 1, Pp 1-15 (2017)
Abstract Background Phosphoinositide 3-kinase γ (PI3Kγ) and PI3Kδ are second messenger-generating enzymes with key roles in proliferation, differentiation, survival, and function of leukocytes. Deficiency of the catalytic subunits p110γ and p110
Externí odkaz: https://doaj.org/article/c0f5e5682f52440982b341ad7f93c5b7
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3
Akademický článek
Prevalence of Borrelia miyamotoi in Ixodes Ticks in Europe and the United States
Autor: Chris D. Crowder, Heather E. Carolan, Megan A. Rounds, Vaclav Honig, Benedikt Mothes, Heike Haag, Oliver Nolte, Ben J. Luft, Libor Grubhoffer, David J. Ecker, Steven E. Schutzer, Mark W. Eshoo
Publikováno v: Emerging Infectious Diseases, Vol 20, Iss 10, Pp 1678-1682 (2014)
Borrelia miyamotoi, a relapsing fever-related spirochete transmitted by Ixodes ticks, has been recently shown to be a human pathogen. To characterize the prevalence of this organism in questing Ixodes ticks, we tested 2,754 ticks for a variety of tic
Externí odkaz: https://doaj.org/article/0af0b19f401d432784bacac15952d3a6
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5
Akademický článek
mRNA-Mediated Gene Supplementation of Toll-Like Receptors as Treatment Strategy for Asthma In Vivo.
Autor: Franziska Zeyer, Benedikt Mothes, Clara Will, Melanie Carevic, Jennifer Rottenberger, Bernd Nürnberg, Dominik Hartl, Rupert Handgretinger, Sandra Beer-Hammer, Michael S D Kormann
Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0154001 (2016)
Asthma is the most common chronic disease in childhood. Although several therapeutic options are currently available to control the symptoms, many drugs have significant side effects and asthma remains an incurable disease. Microbial exposure in earl
Externí odkaz: https://doaj.org/article/beeaad1c81c6423880f268e6c4e20117
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6
Akademický článek
p110γ/δ Double-Deficiency Induces Eosinophilia and IgE Production but Protects from OVA-Induced Airway Inflammation.
Autor: Benedikt Mothes, Kirsten Bucher, Susanne Ammon-Treiber, Matthias Schwab, Roland P Piekorz, Emilio Hirsch, Bernd Nürnberg, Sandra Beer-Hammer
Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0159310 (2016)
The catalytical isoforms p110γ and p110δ of phosphatidylinositide 3-kinase γ (PI3Kγ) and PI3Kδ play an important role in the pathogenesis of asthma. Two key elements in allergic asthma are increased levels of eosinophils and IgE. Dual pharmacolo
Externí odkaz: https://doaj.org/article/acc4a6bdf58f43dcb793411decc84093
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