Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Benedikt J Braun"'
Autor:
Maximilian M Menger, Janine Stutz, Sabrina Ehnert, Andreas K Nussler, Mika F Rollmann, Steven C Herath, Benedikt J Braun, Tim Pohlemann, Michael D Menger, Tina Histing
Publikováno v:
Acta Orthopaedica, Vol 93 (2022)
Background and purpose: In fracture healing, ischemia caused by vascular injuries, chronic vascular diseases, and metabolic comorbidities is one of the major risk factors for delayed union and non-union formation. To gain novel insights into the mole
Externí odkaz:
https://doaj.org/article/5bb5818d97c04b0fa2e44180293bcc3b
Autor:
Steven C Herath, Benedikt J Braun, Mika F Rollmann, Philipp Mörsdorf, Jörg H Holstein, Tim Pohlemann
Publikováno v:
Orthopaedic Surgery, Vol 11, Iss 3, Pp 516-523 (2019)
The present study describes method for autologous bone transplantation to an area of nonunion at the pelvic ring in a way that ensures the best possible bone‐to‐bone interface (“press‐fit”) and provides optimal preconditions for the ingrowt
Externí odkaz:
https://doaj.org/article/50c7ed311f8b497bbf7b8ea93f4c4e41
Autor:
Marcel Orth, Claudia Scheuer, Christina Backes, Andreas Keller, Mika F Rollmann, Benedikt J Braun, Nicole Ludwig, Eckart Meese, Tim Pohlemann, Matthias W Laschke, Michael D Menger, Tina Histing
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0218395 (2019)
Although cellular and molecular mechanisms during the course of bone healing have been thoroughly investigated, the regulation of gene expression by microRNA during bone regeneration is still poorly understood. We hypothesized that nonunion formation
Externí odkaz:
https://doaj.org/article/47949da41a56430984eaa7a7ee9f9696
Autor:
Regina Breinbauer, Michelle Mäling, Sabrina Ehnert, Gunnar Blumenstock, Tobias Schwarz, Johann Jazewitsch, Felix Erne, Marie K. Reumann, Mika F. Rollmann, Benedikt J. Braun, Tina Histing, Andreas K. Nüssler
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Around 10% of fractures lead to complications. With increasing fracture incidences in recent years, this poses a serious burden on the healthcare system, with increasing costs for treatment. In the present study, we aimed to ident
Externí odkaz:
https://doaj.org/article/0b8b4234a0a249449936a2c0819e19d1
Autor:
Maximilian M. Menger, Maximilian Emmerich, Claudia Scheuer, Sandra Hans, Benedikt J. Braun, Steven C. Herath, Mika F. Rollmann, Michael D. Menger, Matthias W. Laschke, Tina Histing
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 173, Iss , Pp 116291- (2024)
The elderly exhibit a reduced healing capacity after fracture, which is often associated with delayed or failed bone healing. This is due to a plethora of factors, such as an impaired bone vascular system and delayed angiogenesis. The phosphodiestera
Externí odkaz:
https://doaj.org/article/95ae5297e8144fb398113b3a0a04a4f9
Autor:
Daniel Truhn, Christian D. Weber, Benedikt J. Braun, Keno Bressem, Jakob N. Kather, Christiane Kuhl, Sven Nebelung
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Large language models (LLMs) have shown potential in various applications, including clinical practice. However, their accuracy and utility in providing treatment recommendations for orthopedic conditions remain to be investigated. Thus, thi
Externí odkaz:
https://doaj.org/article/a36d3ce780e443e59c305d5c6f3b25a3
Autor:
Maximilian M. Menger, David Bauer, Michelle Bleimehl, Claudia Scheuer, Benedikt J. Braun, Steven C. Herath, Mika F. Rollmann, Michael D. Menger, Matthias W. Laschke, Tina Histing
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Non-union formation represents a major complication in trauma and orthopedic surgery. The phosphodiesterase-5 (PDE-5) inhibitor sildenafil has been shown to exert pro-angiogenic and pro-osteogenic effects in vitro and in vivo. Therefore, the
Externí odkaz:
https://doaj.org/article/4b241ce79ed943c3a2546e231eb2064d
Autor:
Daniel Truhn, Christian D. Weber, Benedikt J. Braun, Keno Bressem, Jakob N. Kather, Christiane Kuhl, Sven Nebelung
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/d9fb4563bc754af3b14abaec82c14e4a
Autor:
Maximilian M. Menger, Maximilian Stief, Claudia Scheuer, Mika F. Rollmann, Steven C. Herath, Benedikt J. Braun, Sabrina Ehnert, Andreas K. Nussler, Michael D. Menger, Matthias W. Laschke, Tina Histing
Publikováno v:
Experimental Gerontology, Vol 178, Iss , Pp 112201- (2023)
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as diclofenac, belong to the most prescribed analgesic medication after traumatic injuries. However, there is accumulating evidence that NSAIDs impair fracture healing. Because bone regeneration in
Externí odkaz:
https://doaj.org/article/382a6d9753f949d59f70bffa0c2c5f8c
Autor:
Maximilian M. Menger, Christina Körbel, David Bauer, Michelle Bleimehl, Anne L. Tobias, Benedikt J. Braun, Steven C. Herath, Mika F. Rollmann, Matthias W. Laschke, Michael D. Menger, Tina Histing
Publikováno v:
Photoacoustics, Vol 28, Iss , Pp 100409- (2022)
Non-union formation represents a major complication in trauma surgery. Adequate vascularization has been recognized as vital for bone healing. However, the role of vascularization in the pathophysiology of non-union formation remains elusive. This is
Externí odkaz:
https://doaj.org/article/e20f7a8c4534404b974251e12ca721de