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of 6
pro vyhledávání: '"Benedikt Fabry"'
Autor:
Erik Karl Håkan Clemensson, Laura Emily Clemensson, Benedikt Fabry, Stefanie Flunkert, Olaf Riess, Robert Wronski, Huu Phuc Nguyen
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213755 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0173232.].
Externí odkaz:
https://doaj.org/article/9d1a30ce56c64e6d9f5b3b2008e0eabd
Autor:
Erik Karl Håkan Clemensson, Laura Emily Clemensson, Benedikt Fabry, Stefanie Flunkert, Olaf Riess, Robert Wronski, Huu Phuc Nguyen
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173232 (2017)
Huntington disease is an inherited neurodegenerative disorder characterized by motor, cognitive, psychiatric and metabolic symptoms. We recently published a study describing that the BACHD rat model of HD shows an obesity phenotype, which might affec
Externí odkaz:
https://doaj.org/article/e6c9c9a0438d4ce2a2d2aee16739ca2e
Autor:
Erik Karl Håkan Clemensson, Laura Emily Clemensson, Benedikt Fabry, Stefanie Flunkert, Olaf Riess, Robert Wronski, Huu Phuc Nguyen
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213755 (2019)
PLoS ONE
PLoS ONE
Huntington disease is an inherited neurodegenerative disorder characterized by motor, cognitive, psychiatric and metabolic symptoms. We recently published a study describing that the BACHD rat model of HD shows an obesity phenotype, which might affec
Autor:
Hoa Huu Phuc Nguyen, Robert Wronski, Benedikt Fabry, Birgit Hutter-Paier, Stefanie Flunkert, Tina Loeffler
Publikováno v:
Models for HD.
Background The BACHD rat is by now a well characterized animal model of Huntington’s disease (HD), presenting several disease relevant symptoms and pathologies. The BACHD rat represents one of the few animal models that overexpresses the full lengt
Autor:
Bernd J. Pichler, Janice Stricker-Shaver, Carsten Calaminus, Huu Phuc Nguyen, Benedikt Fabry, Olaf Riess, Lamya S. Shihabuddin, Libo Yu-Taeger, Elisabeth Singer, Lisa M. Stanek
Publikováno v:
Pathogenic mechanisms.
Background In Huntington disease (HD), the negative impacts of metabolic dysfunctions heavily affects the quality of life of patients. As energy metabolism is centrally regulated by the hypothalamus via a number of proteins, we hypothesize that mutan
Autor:
Benedikt Fabry, Birgit Hutter-Paier, Stefanie Flunkert, LE Clemens, Robert Wronski, Hoa Huu Phuc Nguyen
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 87:A29.2-A29
Background The BACHD rat overexpresses a bacterial artificial chromosome (BAC) with the full length human mutant huntingtin (mHTT) with 97 alternating CAA/CAG repeats, which are the sole cause of disease onset. BACHD rats display mHTT aggregates and