Zobrazeno 1 - 10
of 524
pro vyhledávání: '"Benedikt, Hallgrímsson"'
Autor:
Michiel Vanneste, Hanne Hoskens, Seppe Goovaerts, Harold Matthews, Jay Devine, Jose D. Aponte, Joanne Cole, Mark Shriver, Mary L. Marazita, Seth M. Weinberg, Susan Walsh, Stephen Richmond, Ophir D. Klein, Richard A. Spritz, Hilde Peeters, Benedikt Hallgrímsson, Peter Claes
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Human craniofacial shape is highly variable yet highly heritable with numerous genetic variants interacting through multiple layers of development. Here, we hypothesize that Mendelian phenotypes represent the extremes of a phenotypic spectru
Externí odkaz:
https://doaj.org/article/53249a4e52054d56af916527ff5bdc39
Autor:
Richards, Christina L.
Publikováno v:
Integrative and Comparative Biology, 2012 Oct 01. 52(4), 547-549.
Externí odkaz:
http://dx.doi.org/10.1093/icb/ics108
Autor:
Moczek, Armin P., Valena, Sophie
Publikováno v:
The Quarterly Review of Biology, 2012 Mar . 87(1), 69-70.
Externí odkaz:
https://www.jstor.org/stable/10.1086/663908
Autor:
True, John
Publikováno v:
The Quarterly Review of Biology, 2006 Dec . 81(4), 397-397.
Externí odkaz:
https://www.jstor.org/stable/10.1086/511561
Autor:
Quentin Jean-Baptiste Horta-Lacueva, Zophonías Oddur Jónsson, Dagny A. V. Thorholludottir, Benedikt Hallgrímsson, Kalina Hristova Kapralova
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Adaptive evolution may be influenced by canalization, the buffering of developmental processes from environmental and genetic perturbations, but how this occurs is poorly understood. Here, we explore how gene expression variability evolves i
Externí odkaz:
https://doaj.org/article/55eb76141287402f9e1ba214d4d1475e
Autor:
Jay Devine, Marta Vidal-García, Wei Liu, Amanda Neves, Lucas D. Lo Vercio, Rebecca M. Green, Heather A. Richbourg, Marta Marchini, Colton M. Unger, Audrey C. Nickle, Bethany Radford, Nathan M. Young, Paula N. Gonzalez, Robert E. Schuler, Alejandro Bugacov, Campbell Rolian, Christopher J. Percival, Trevor Williams, Lee Niswander, Anne L. Calof, Arthur D. Lander, Axel Visel, Frank R. Jirik, James M. Cheverud, Ophir D. Klein, Ramon Y. Birnbaum, Amy E. Merrill, Rebecca R. Ackermann, Daniel Graf, Myriam Hemberger, Wendy Dean, Nils D. Forkert, Stephen A. Murray, Henrik Westerberg, Ralph S. Marcucio, Benedikt Hallgrímsson
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-18 (2022)
Abstract Complex morphological traits are the product of many genes with transient or lasting developmental effects that interact in anatomical context. Mouse models are a key resource for disentangling such effects, because they offer myriad tools f
Externí odkaz:
https://doaj.org/article/7defe75069d24f29bca1c5a94da00059
Autor:
Jay Devine, Marta Vidal-García, Wei Liu, Amanda Neves, Lucas D. Lo Vercio, Rebecca M. Green, Heather A. Richbourg, Marta Marchini, Colton M. Unger, Audrey C. Nickle, Bethany Radford, Nathan M. Young, Paula N. Gonzalez, Robert E. Schuler, Alejandro Bugacov, Campbell Rolian, Christopher J. Percival, Trevor Williams, Lee Niswander, Anne L. Calof, Arthur D. Lander, Axel Visel, Frank R. Jirik, James M. Cheverud, Ophir D. Klein, Ramon Y. Birnbaum, Amy E. Merrill, Rebecca R. Ackermann, Daniel Graf, Myriam Hemberger, Wendy Dean, Nils D. Forkert, Stephen A. Murray, Henrik Westerberg, Ralph S. Marcucio, Benedikt Hallgrímsson
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/be08db417e494e3e9e3dd747d51524cb
Illuminating the processes and patterns that link genotype to phenotype, epigenetics seeks to explain features, characters, and developmental mechanisms that can only be understood in terms of interactions that arise above the level of the gene. With
Autor:
Megan Null, Feyza Yilmaz, David Astling, Hung-Chun Yu, Joanne B. Cole, Benedikt Hallgrímsson, Stephanie A. Santorico, Richard A. Spritz, Tamim H. Shaikh, Audrey E. Hendricks
Publikováno v:
HGG Advances, Vol 3, Iss 1, Pp 100082- (2022)
Similarity in facial characteristics between relatives suggests a strong genetic component underlies facial variation. While there have been numerous studies of the genetics of facial abnormalities and, more recently, single nucleotide polymorphism (
Externí odkaz:
https://doaj.org/article/33d2bde0be194f3296718f47b89ac036
Autor:
Jose D Aponte, David C Katz, Daniela M Roth, Marta Vidal-García, Wei Liu, Fernando Andrade, Charles C Roseman, Steven A Murray, James Cheverud, Daniel Graf, Ralph S Marcucio, Benedikt Hallgrímsson
Publikováno v:
eLife, Vol 10 (2021)
Realistic mappings of genes to morphology are inherently multivariate on both sides of the equation. The importance of coordinated gene effects on morphological phenotypes is clear from the intertwining of gene actions in signaling pathways, gene reg
Externí odkaz:
https://doaj.org/article/88b99fdbe9bf4745aa04504d6544da97