Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Benedikt, Binder"'
Autor:
Nicholas M. Provine, Benedikt Binder, Michael E. B. FitzPatrick, Anita Schuch, Lucy C. Garner, Kate D. Williamson, Bonnie van Wilgenburg, Robert Thimme, Paul Klenerman, Maike Hofmann
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Mucosal-associated invariant T (MAIT) cells are innate-like T cells abundant in humans that can be activated in a TCR-independent manner by inflammatory and antiviral cytokines. In humans, the capacity for TCR-independent activation is functionally l
Externí odkaz:
https://doaj.org/article/d4d95a5365344813bf961464d276c02a
Publikováno v:
Critical reviews in immunology. 41(5)
Mucosal-associated invariant T (MAIT) cells are a group of unconventional T cells that have come into focus of researchers in the past years. They are abundant in humans and enriched in tissues like the liver. Their roles in physiological immune proc
Autor:
Saskia Killmer, Marcus Panning, Janine Kemming, Robert Thimme, Alexandra Nieters, Christoph Neumann-Haefelin, Maike Hofmann, Franziska Daul, Henrik E. Mei, Florian Emmerich, Axel Schulz, Benedikt Binder, David Price, Sagar, Tobias Boettler, Isabel Schulien, Hendrik Luxenburger, Bertram Bengsch, Lea M. Seidel, Martin Schwemmle, Daniela Huzly, Siegbert Rieg, Marilyn Salvat Lago, Cornelius F. Waller, Daniel Duerschmied, Dominik Bettinger, Oezlem Sogukpinar, Georg Kochs, Valerie Oberhardt, Katharina Wild, Sian Llewellyn-Lacey, Annegrit Decker
Publikováno v:
Nature Medicine
Emerging data indicate that SARS-CoV-2-specific CD8+ T cells targeting different viral proteins are detectable in up to 70% of convalescent individuals. However, very little information is currently available about the abundance, phenotype, functiona
Publikováno v:
Current Hepatology Reports. 19:337-344
Purpose of Review Chronic Hepatitis B Virus (HBV) Infection is a major global health burden. Currently, a curative therapy does not exist; thus, there is an urgent need for new therapeutical options. Viral elimination in the natural course of infecti
Autor:
Benedikt Binder, Robert Thimme
Publikováno v:
J Clin Invest
Chronic hepatitis C virus (HCV) infection is characterized by persistent high-level viremia and defective cellular immunity, including a lack of functional HCV-specific CD4(+) T cells. We previously described an exceptional period of viral control th
Autor:
Dominik Bettinger, Benedikt Binder, Laura Muller, Lukas Sturm, Jan Patrick Huber, Robert Thimme, Michael Schultheiss
Publikováno v:
European journal of gastroenterologyhepatology. 33(1S Suppl 1)
BACKGROUND AND AIMS Several studies have reported associations of proton pump inhibitor (PPI) treatment with the incidence of complications and even increased mortality in patients with liver cirrhosis. Up to now, there are no studies on the impact o
Autor:
Isabel, Schulien, Janine, Kemming, Valerie, Oberhardt, Katharina, Wild, Lea M, Seidel, Saskia, Killmer, Sagar, Franziska, Daul, Marilyn, Salvat Lago, Annegrit, Decker, Hendrik, Luxenburger, Benedikt, Binder, Dominik, Bettinger, Oezlem, Sogukpinar, Siegbert, Rieg, Marcus, Panning, Daniela, Huzly, Martin, Schwemmle, Georg, Kochs, Cornelius F, Waller, Alexandra, Nieters, Daniel, Duerschmied, Florian, Emmerich, Henrik E, Mei, Axel Ronald, Schulz, Sian, Llewellyn-Lacey, David A, Price, Tobias, Boettler, Bertram, Bengsch, Robert, Thimme, Maike, Hofmann, Christoph, Neumann-Haefelin
Publikováno v:
Nature medicine. 27(1)
Emerging data indicate that SARS-CoV-2-specific CD8
Autor:
Lea M. Seidel, Janine Kemming, Isabel Schulien, David Price, Saskia Killmer, Franziska Daul, Georg Kochs, Siegbert Rieg, Marilyn Salvat Lago, Marcus Panning, Sian Llewellyn-Lacey, Christoph Neumann-Haefelin, Henrik E. Mei, Florian Emmerich, Oezlem Sogukpinar, Valerie Oberhardt, Robert Thimme, Sagar, Axel Schulz, Cornelius F. Waller, Benedikt Binder, Dominik Bettinger, Alexandra Nieters, Annegrit Decker, Katharina Wild, Daniela Huzly, Daniel Duerschmied, Hendrik Luxenburger, Bertram Bengsch, Martin Schwemmle, Maike Hofmann, Tobias Boettler
CD8+ T cells are critical for the elimination and long-lasting protection of many viral infections, but their role in the current SARS-CoV-2 pandemic is unclear. Emerging data indicates that SARS-CoV-2-specific CD8+ T cells are detectable in the majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8ac64fa7f1ef8c5843ae4d6aa959efa
https://doi.org/10.1101/2020.08.13.249433
https://doi.org/10.1101/2020.08.13.249433
Autor:
Maike Hofmann, Benedikt Binder, Robert Thimme, A Hoh, B van Wilgenburg, Paul Klenerman, A Schuch
Publikováno v:
Zeitschrift für Gastroenterologie. 54:1343-1404
Autor:
Stephan Urban, Robert Thimme, Alexander Hoh, Michael Nassal, Yi Ni, Maximilian Heeg, Hubert E. Blum, Benedikt Binder, Nadine Hennecke, Maike Hofmann, A Schuch, Ulrike Protzer
Publikováno v:
J. Virol. 89, 7433-7438 (2015)
CD8 + T cells are the main effector lymphocytes in the control of hepatitis B virus (HBV) infection. However, limitations of model systems, such as low infection rates, restrict mechanistic studies of HBV-specific CD8 + T cells. Here, we established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12e0878f3e26fa5b7c883915863c23d
https://europepmc.org/articles/PMC4473563/
https://europepmc.org/articles/PMC4473563/