Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Benedicte Danis"'
Autor:
Prashant K. Srivastava, Jonathan van Eyll, Patrice Godard, Manuela Mazzuferi, Andree Delahaye-Duriez, Juliette Van Steenwinckel, Pierre Gressens, Benedicte Danis, Catherine Vandenplas, Patrik Foerch, Karine Leclercq, Georges Mairet-Coello, Alvaro Cardenas, Frederic Vanclef, Liisi Laaniste, Isabelle Niespodziany, James Keaney, Julien Gasser, Gaelle Gillet, Kirill Shkura, Seon-Ah Chong, Jacques Behmoaras, Irena Kadiu, Enrico Petretto, Rafal M. Kaminski, Michael R. Johnson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
The identification of new drug targets is highly challenging, particularly for diseases of the brain. This study describes a general computational gene regulatory framework called CRAFT for drug target discovery, and the authors use CRAFT to identify
Externí odkaz:
https://doaj.org/article/c0cffc3635504945bbe2f39f8175da2f
Autor:
Oliver Brain, Barry J. Campbell, Benedicte Danis, John Baker, Tica Pichulik, Derek P. Jewell, Philip Allan, David J. P. Ferguson, Alison Simmons, Rachel Cooney
Publikováno v:
Nature Medicine. 16:90-97
Nucleotide-binding oligomerization domain-containing-2 (NOD2) acts as a bacterial sensor in dendritic cells (DCs), but it is not clear how bacterial recognition links with antigen presentation after NOD2 stimulation. NOD2 variants are associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be2acfbc03c82d80c26ff419a6ce71c
https://doi.org/10.1038/nm.2069
https://doi.org/10.1038/nm.2069
Autor:
Tica, Pichulik, Elham, Khatamzas, Xiao, Liu, Oliver, Brain, Magno, Delmiro Garcia, Alasdair, Leslie, Benedicte, Danis, Alice, Mayer, Dilair, Baban, Jiannis, Ragoussis, Alexander N R, Weber, Alison, Simmons
Publikováno v:
European Journal of Immunology
MicroRNAs are important posttranscriptional regulators of gene expression, which have been shown to fine‐tune innate immune responses downstream of pattern recognition receptor (PRR) signaling. This study identifies miR‐650 as a novel PRR‐respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea6cf4aeabb5587a99ec709b3add77fc
https://pubmed.ncbi.nlm.nih.gov/26460926
https://pubmed.ncbi.nlm.nih.gov/26460926
Autor:
Manuela, Mazzuferi, Gaurav, Kumar, Jonathan, van Eyll, Benedicte, Danis, Patrik, Foerch, Rafal M, Kaminski
Publikováno v:
Annals of neurology. 74(4)
Epigenetic mechanisms involved in transcriptional regulation of multiple molecular pathways are potentially attractive therapeutic interventions for epilepsy, because single target therapies are unlikely to provide both anticonvulsant and disease-mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dfb022ea45e8afbdd90147bda2bbc507
https://pubmed.ncbi.nlm.nih.gov/23686862
https://pubmed.ncbi.nlm.nih.gov/23686862
Autor:
Alison Simmons, Rachel Cooney, John Baker, Dilair Baban, Derek P. Jewell, Oliver Brain, Jiannis Ragoussis, Tica Pichulik, Benedicte Danis
Publikováno v:
Gastroenterology. 136:A-249
Background Nucleotide-binding oligomerization domain containing 2 (NOD2) is an intracellular pattern-recognition receptor activated by muramyldipeptide, a component of peptidoglycan contained in bacterial cell walls. Mutations in the NOD2 gene that o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ef3f6376ffb9356f8cbb9335d5094b8
https://doi.org/10.1016/s0016-5085(09)61127-6
https://doi.org/10.1016/s0016-5085(09)61127-6