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Perspectives of Adult Singaporeans toward Potential Policies to Reduce the Consumption of Sugar Sweetened Beverages—A Cross-Sectional Study

Autor: Siong Gim Ong, Jiali Yao, Albert Teng, Salome A. Rebello, Jing Yuan Tan, Nan Luo, Benedict Ng

Publikováno v: Nutrients, Vol 13, Iss 4231, p 4231 (2021)
Nutrients; Volume 13; Issue 12; Pages: 4231
Nutrients

Excessive consumption of sugar sweetened beverages (SSB) is of growing concern, and several countries are implementing measures to reduce SSB consumption. Understanding perceptions towards SSB policies is crucial to prioritize policy actions and to e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1223edfa2b08446886a4c5428f3ddc7
https://www.mdpi.com/2072-6643/13/12/4231

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Whole genome and biomarker analysis of patients with recurrent glioblastoma on bevacizumab: A subset analysis of the CABARET trial

Autor: Lauren R. Olafson, Kerrie L. McDonald, Benedict Ng, Elizabeth H Barnes, Sonia Yip, Mark Rosenthal, Kathryn M. Field, Terrance Grant Johns, John Simes, Robert W. Rapkins, Madeleine Byrnes, Anna H. Siddell, Sheri Nixdorf, Anna K. Nowak

Publikováno v: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 70

The CABARET trial (ACTRN12610000915055) reported no difference in overall survival (OS) between patients with recurrent glioblastoma (GBM) randomized to either bevacizumab monotherapy or bevacizumab plus carboplatin. However, a subset of patients sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58fb4740475e989356e6f9663f5d59fe
https://pubmed.ncbi.nlm.nih.gov/31582283

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A case study of a long-term glioblastoma survivor with unmethylated

Autor: Toni Rose, Jue, Lauren R, Olafson, Anna H, Siddell, Robert W, Rapkins, Benedict, Ng, Julia X M, Yin, Victor M, Lu, Sylvia A, Chung, Shane P, Whittaker, Matthew, Davies, Jacob M, Fairhall, Elizabeth J, Hovey, Kerrie L, McDonald

Publikováno v: Cold Spring Harbor Molecular Case Studies

Effective treatments that extend survival of malignant brain tumor glioblastoma (GBM) have not changed in more than a decade; however, there exists a minority patient group (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1e709dbd92da2130b17358ed3e32e73c
https://pubmed.ncbi.nlm.nih.gov/31160353

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Lynch Syndrome Associated with Two MLH1 Promoter Variants and Allelic Imbalance of MLH1 Expression

Autor: Benedict Ng, Christa Schmidt, Deborah Packham, Luke B. Hesson, Michael Fields, Robyn L. Ward, Jason W. H. Wong, Chau-To Kwok, Matthew A Sloane, Andrea Nuñez

Publikováno v: Human Mutation

Lynch syndrome is a hereditary cancer syndrome caused by a constitutional mutation in one of the mismatch repair genes. The implementation of predictive testing and targeted preventative surveillance is hindered by the frequent finding of sequence va

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9382bc93be49ce3ab56e48160f61c469
http://europepmc.org/articles/PMC4682451

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Altered promoter nucleosome positioning is an early event in gene silencing

Autor: Benedict Ng, Michael J. Bourke, Sameer Srivastava, Nicholas J. Hawkins, Jason W. H. Wong, Luke B. Hesson, Robyn L. Ward, Andrea Nuñez, Mathew A. Sloane

Publikováno v: Epigenetics. 9:1422-1430

Gene silencing in cancer frequently involves hypermethylation and dense nucleosome occupancy across promoter regions. How a promoter transitions to this silent state is unclear. Using colorectal adenomas, we investigated nucleosome positioning, DNA m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc7797e3c811698bb1aff341da66cbb
https://doi.org/10.4161/15592294.2014.970077

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A case study of a long-term glioblastoma survivor with unmethylated MGMT and hypermutated genotype

Autor: Victor M. Lu, Toni Rose Jue, Julia X. M. Yin, Anna H. Siddell, Robert W. Rapkins, Jacob Fairhall, Lauren R. Olafson, Sylvia A. Chung, Matthew J Davies, Elizabeth Hovey, Shane Whittaker, Kerrie L. McDonald, Benedict Ng

Publikováno v: Molecular Case Studies. 5:a003251

Effective treatments that extend survival of malignant brain tumor glioblastoma (GBM) have not changed in more than a decade; however, there exists a minority patient group (MGMT unmethylated GBM. The patient was progression-free for 23 mo. Fresh pri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f2cd5edb9f92cf473b70bf94c234cd5
https://doi.org/10.1101/mcs.a003251

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Integrated Genetic, Epigenetic, and Transcriptional Profiling Identifies Molecular Pathways in the Development of Laterally Spreading Tumors

Autor: Caroline E. Ford, Regina Ryan, John E. Pimanda, Michael J. Bourke, Ashraf Dower, Luke B. Hesson, Chau To Kwok, Dominik Beck, Andrea Nuñez, Nicholas J. Hawkins, Sameer Srivastava, Benedict Ng, Deborah Packham, Peter Zarzour, Jason W. H. Wong, Robyn L. Ward, Mathew A. Sloane

Publikováno v: Molecular cancer research : MCR. 14(12)

Laterally spreading tumors (LST) are colorectal adenomas that develop into extremely large lesions with predominantly slow progression to cancer, depending on lesion subtype. Comparing and contrasting the molecular profiles of LSTs and colorectal can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3257caec83df57ba962076fb3233500
https://pubmed.ncbi.nlm.nih.gov/27671336

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