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of 19
pro vyhledávání: '"Benedict M. Matern"'
Autor:
Benedict M. Matern, Eric Spierings, Selle Bandstra, Abeer Madbouly, Stefan Schaub, Eric T. Weimer, Matthias Niemann
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionModern histocompatibility algorithms depend on the comparison and analysis of high-resolution HLA protein sequences and structures, especially when considering epitope-based algorithms, which aim to model the interactions involved in anti
Externí odkaz:
https://doaj.org/article/837d41c767274cfdaaea7944fce232b1
Autor:
Matthias Niemann, Yara Strehler, Nils Lachmann, Fabian Halleck, Klemens Budde, Gideon Hönger, Stefan Schaub, Benedict M. Matern, Eric Spierings
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Development of donor-specific human leukocyte antigen (HLA) antibodies (DSA) remains a major risk factor for graft loss following organ transplantation, where DSA are directed towards patches on the three-dimensional structure of the respective organ
Externí odkaz:
https://doaj.org/article/bbd636c2afcf480f920489f8af6db569
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Histocompatibility in solid-organ transplantation has a strong impact on long-term graft survival. Although recent advances in matching of both B-cell epitopes and T-cell epitopes have improved understanding of allorecognition, the immunogenic determ
Externí odkaz:
https://doaj.org/article/4aad96b447fd4081a61ee2fc3b734450
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Predicted Indirectly ReCognizable Human Leukocyte Antigen (HLA) Epitopes (PIRCHE) are known to be a significant risk factor for the development of donor HLA-specific antibodies after organ transplantation. Most previous studies on PIRCHE limited thei
Externí odkaz:
https://doaj.org/article/07b37444db6548e083a9b6a64c939cb0
Autor:
Emma T. M. Peereboom, Benedict M. Matern, Toshihide Tomosugi, Matthias Niemann, Julia Drylewicz, Irma Joosten, Wil A. Allebes, Arnold van der Meer, Luuk B. Hilbrands, Marije C. Baas, Franka E. van Reekum, Marianne C. Verhaar, Elena G. Kamburova, Marc A. J. Seelen, Jan Stephan Sanders, Bouke G. Hepkema, Annechien J. Lambeck, Laura B. Bungener, Caroline Roozendaal, Marcel G. J. Tilanus, Christien E. Voorter, Lotte Wieten, Elly M. van Duijnhoven, Mariëlle A. C. J. Gelens, Maarten H. L. Christiaans, Frans J. van Ittersum, Azam Nurmohamed, Neubury M. Lardy, Wendy Swelsen, Karlijn A. van der Pant, Neelke C. van der Weerd, Ineke J. M. ten Berge, Fréderike J. Bemelman, Aiko P. J. de Vries, Johan W. de Fijter, Michiel G. H. Betjes, Dave L. Roelen, Frans H. Claas, Henny G. Otten, Sebastiaan Heidt, Arjan D. van Zuilen, Takaaki Kobayashi, Kirsten Geneugelijk, Eric Spierings
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
CD4+ T-helper cells play an important role in alloimmune reactions following transplantation by stimulating humoral as well as cellular responses, which might lead to failure of the allograft. CD4+ memory T-helper cells from a previous immunizing eve
Externí odkaz:
https://doaj.org/article/304c2f59ef3743a597b164b0c8125533
Autor:
Benedict M. Matern, Matthias Niemann, Ioannis Nemparis, Andreas Schimanski, Emma T. M. Peereboom, Cynthia S. M. Kramer, Sebastiaan Heidt, Eric Spierings
Publikováno v:
HLA. 101:484-495
Publikováno v:
Transplantation. 106(12)
Single-cell technologies open up new opportunities to explore the behavior of cells at the individual level. For solid organ transplantation, single-cell technologies can provide in-depth insights into the underlying mechanisms of the immunological p
Autor:
Burcu Duygu, Marcel G.J. Tilanus, Mathijs Groeneweg, Benedict M. Matern, Christina E.M. Voorter, Lotte Wieten, Timo I. Olieslagers
Publikováno v:
Journal of Molecular Diagnostics, 22(7), 912-919. Elsevier Science
Matching of human leukocyte antigen (HLA) gene polymorphisms by high-resolution DNA sequence analysis is the gold standard for determining compatibility between patient and donor for hematopoietic stem cell transplantation. Single-molecule sequencing
Publikováno v:
Immunogenetics
Immunogenetics, 72(6-7), 339-346. Springer Verlag
Immunogenetics, 72(6-7), 339-346. Springer Verlag
The HLA-B15 typing by serological approaches defined the serological subgroups (or splits) B62, B63, B75, B76, B77 and B70 (B71 and B72). The scarcity of sera with specific anti-HLA antibodies makes the serological typing method difficult to discrimi
Autor:
Patricia Martinez, Benedict M. Matern, Marcel G.J. Tilanus, Lloyd D'Orsogna, Linh Truong, Dianne De Santis
Publikováno v:
HLA, 95(2), 104-116. Wiley
The rapid progress of HLA typing techniques has contributed to improving the outcome of haematopoietic stem cell transplantation (HSCT). However, unambiguous HLA typing remains challenging. Next generation sequencing (NGS) has been shown to resolve t