Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Benedict B Benigno"'
Autor:
Shubin W Shahab, Lilya V Matyunina, Roman Mezencev, L DeEtte Walker, Nathan J Bowen, Benedict B Benigno, John F McDonald
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22508 (2011)
MicroRNAs (miRNAs) are short (∼22 nucleotides) regulatory RNAs that can modulate gene expression and are aberrantly expressed in many diseases including cancer. Previous studies have shown that miRNAs inhibit the translation and facilitate the degr
Externí odkaz:
https://doaj.org/article/b68aae28e5354e80b6533ef8e46bfd42
Autor:
Carlos S Moreno, Lilya Matyunina, Erin B Dickerson, Nina Schubert, Nathan J Bowen, Sanjay Logani, Benedict B Benigno, John F McDonald
Publikováno v:
PLoS ONE, Vol 2, Iss 5, p e441 (2007)
Gene expression profiles of malignant tumors surgically removed from ovarian cancer patients pre-treated with chemotherapy (neo-adjuvant) prior to surgery group into two distinct clusters. One group clusters with carcinomas from patients not pre-trea
Externí odkaz:
https://doaj.org/article/4addfdca0fe54f898a25e9cd97a6726a
Autor:
Nicholas E. Stone, Abhishek Raj, Katherine M. Young, Adam P. DeLuca, Fatima Ezahra Chrit, Budd A. Tucker, Alexander Alexeev, John McDonald, Benedict B. Benigno, Todd Sulchek
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The isolation of a patient's metastatic cancer cells is the first, enabling step toward treatment of that patient using modern personalized medicine techniques. Whereas traditional standard-of-care approaches select treatments for cancer pat
Externí odkaz:
https://doaj.org/article/0613c178092047e293ef608a8167e235
Autor:
Mengnan Zhang, Lilya V. Matyunina, L. DeEtte Walker, Weixuan Chen, Haopeng Xiao, Benedict B. Benigno, Ronghu Wu, John F. McDonald
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract High-throughput technologies have identified significant changes in patterns of mRNA expression over cancer development but the functional significance of these changes often rests upon the assumption that observed changes in levels of mRNA
Externí odkaz:
https://doaj.org/article/7897ad282e104afabe0c3c6fd98e370c
Autor:
John F. McDonald, Facundo M. Fernández, Alexander Gray, Benedict B. Benigno, Roman Mezencev, L. DeEtte Walker, Wei Guan, Manshui Zhou
Supplementary Figures 1-5, Supplementary Tables 1-2 from Rapid Mass Spectrometric Metabolic Profiling of Blood Sera Detects Ovarian Cancer with High Accuracy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e8839329e0d28d5b5226fc75e3234c
https://doi.org/10.1158/1055-9965.22435762.v1
https://doi.org/10.1158/1055-9965.22435762.v1
Autor:
John F. McDonald, Facundo M. Fernández, Alexander Gray, Benedict B. Benigno, Roman Mezencev, L. DeEtte Walker, Wei Guan, Manshui Zhou
Background: Ovarian cancer diagnosis is problematic because the disease is typically asymptomatic, especially at the early stages of progression and/or recurrence. We report here the integration of a new mass spectrometric technology with a novel sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2acdf759f426654c6a9698290f612d37
https://doi.org/10.1158/1055-9965.c.6515089
https://doi.org/10.1158/1055-9965.c.6515089
Autor:
A. Raj, Katherine M. Young, Benedict B. Benigno, Todd Sulchek, Alexander Alexeev, Budd A. Tucker, Nicholas Stone, Adam P. DeLuca, Fatima Ezahra Chrit, John F. McDonald
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
The isolation of a patient's metastatic cancer cells is the first, enabling step toward treatment of that patient using modern personalized medicine techniques. Whereas traditional standard-of-care approaches select treatments for cancer patients bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb7b0c686b40f54afaada7e93d4d0f5
https://doaj.org/article/0613c178092047e293ef608a8167e235
https://doaj.org/article/0613c178092047e293ef608a8167e235
Autor:
Mert Boya, Tevhide Ozkaya-Ahmadov, Brandi E. Swain, Chia-Heng Chu, Norh Asmare, Ozgun Civelekoglu, Ruxiu Liu, Dohwan Lee, Sherry Tobia, Shweta Biliya, L. DeEtte McDonald, Bassel Nazha, Omer Kucuk, Martin G. Sanda, Benedict B. Benigno, Carlos S. Moreno, Mehmet A. Bilen, John F. McDonald, A. Fatih Sarioglu
Publikováno v:
Nature Communications. 13
Extremely rare circulating tumor cell (CTC) clusters are both increasingly appreciated as highly metastatic precursors and virtually unexplored. Technologies are primarily designed to detect single CTCs and often fail to account for the fragility of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42b1e4c9ce792272df788d287d074251
https://doi.org/10.1038/s41467-022-31009-9
https://doi.org/10.1038/s41467-022-31009-9
Autor:
IM Bover Barcelo, Jørn Herrstedt, P. Wang, Dominique Berton-Rigaud, Bobbie J. Rimel, A. du Bois, Sven Mahner, Mansoor Raza Mirza, F.A. de Jong, Elsa Kalbacher, Divya Gupta, Ignace Vergote, Benedict B. Benigno, Anne Dørum, Domenica Lorusso, Paul Bessette, Joseph Buscema, S. Lau, Ursula A. Matulonis, A. Casado Herráez, Jonathan A. Ledermann, Tally Levy
Publikováno v:
Mirza, M R, Benigno, B, Dørum, A, Mahner, S, Bessette, P, Barceló, I B, Berton-Rigaud, D, Ledermann, J A, Rimel, B J, Herrstedt, J, Lau, S, du Bois, A, Herráez, A C, Kalbacher, E, Buscema, J, Lorusso, D, Vergote, I, Levy, T, Wang, P, de Jong, F A, Gupta, D & Matulonis, U A 2020, ' Long-term safety in patients with recurrent ovarian cancer treated with niraparib versus placebo : Results from the phase III ENGOT-OV16/NOVA trial ', Gynecologic Oncology, vol. 159, no. 2, pp. 442-448 . https://doi.org/10.1016/j.ygyno.2020.09.006
OBJECTIVE: Niraparib is a poly(ADP-ribose) polymerase (PARP) inhibitor approved for use in heavily pretreated patients and as maintenance treatment in patients with newly-diagnosed or recurrent ovarian cancer following a response to platinum-based ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09e124717329b457b57f0ae200c6650
https://doi.org/10.1016/j.ygyno.2020.09.006
https://doi.org/10.1016/j.ygyno.2020.09.006
Autor:
Paul Sabbatini, Kian Behbakht, Lee-may Chen, Carolyn Y. Muller, Roisin E. O'Cearbhaill, Carol Aghajanian, Benedict B. Benigno, Krishnansu S. Tewari, Emily Berry, Parviz Hanjani, Heather A. Lankes, Joseph A. Lucci, Nick M. Spirtos, Matthew A. Powell, Wei Deng
Publikováno v:
Gynecologic Oncology. 155:393-399
Objective Early-phase data have demonstrated induction of antibody responses to a polyvalent vaccine conjugate (Globo-H, GM2, MUC1-TN, TF) with adjuvant OPT-821. We sought to determine if this combination decreases the hazard of progression or death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89f8569205a196686ac45642bc56a77
https://doi.org/10.1016/j.ygyno.2019.09.015
https://doi.org/10.1016/j.ygyno.2019.09.015