Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Benedict, Fallet"'
Autor:
Doron Merkler, Ingrid Wagner, Mario Kreutzfeldt, Karen Cornille, Tobias M. Brunner, Marco Künzli, David Schreiner, Kerstin Narr, Mirela Dimitrova, Yusuf I. Ertuna, Lukas Bestmann, Benedict Fallet, Max Löhning, Carolyn G. King, Tiago Jose Abreu Mota, Anna-Friederike Marx, Florian Geier, Katrin Martin, Daniel D. Pinschewer
Publikováno v:
Proc Natl Acad Sci U S A
Chronic viral infections subvert protective B cell immunity. An early type I interferon (IFN-I)-driven bias to short-lived plasmablast differentiation leads to clonal deletion, so-called "decimation," of antiviral memory B cells. Therefore, prophylac
Autor:
Mehmet, Sahin, Melissa M, Remy, Benedict, Fallet, Rami, Sommerstein, Marianna, Florova, Anna, Langner, Katja, Klausz, Tobias, Straub, Mario, Kreutzfeldt, Ingrid, Wagner, Cinzia T, Schmidt, Pauline, Malinge, Giovanni, Magistrelli, Shozo, Izui, Hanspeter, Pircher, J Sjef, Verbeek, Doron, Merkler, Matthias, Peipp, Daniel D, Pinschewer
Publikováno v:
Cell reports. 38(5)
Across the animal kingdom, multivalency discriminates antibodies from all other immunoglobulin superfamily members. The evolutionary forces conserving multivalency above other structural hallmarks of antibodies remain, however, incompletely defined.
Autor:
Yusuf I, Ertuna, Benedict, Fallet, Anna-Friederike, Marx, Mirela, Dimitrova, Anna Lena, Kastner, Ingrid, Wagner, Doron, Merkler, Daniel D, Pinschewer
Publikováno v:
Cell reports. 37(9)
Passive antibody therapy and vectored antibody gene delivery (VAGD) in particular offer an innovative approach to combat persistent viral diseases. Here, we exploit a small animal model to investigate synergies of VAGD with the host's endogenous immu
Publikováno v:
Rheumatology (Oxford, England)
Publikováno v:
Arthritis & Rheumatology
Over 4 million cases of Coronavirus disease 2019 (COVID‐19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) have been confirmed worldwide. Up to 20% of cases develop severe disease and the fatality rate are high
Autor:
Lukas Flatz, Beat A. Kaufmann, Tommy Regen, Toni Rieger, Lukas Bestmann, Mario Kreutzfeldt, Benedict Fallet, Daniel D. Pinschewer, Melissa Remy, Uwe-Karsten Hanisch, Doron Merkler, Lifen Xu, Camille Doras, Mehmet Sahin
Publikováno v:
Cell Host & Microbe, Vol. 22, No 3 (2017) pp. 354-365.e5
Arenaviruses such as Lassa virus (LASV) cause hemorrhagic fever. Terminal shock is associated with a systemic cytokine storm, but the mechanisms are ill defined. Here we used HLA-A2-expressing mice infected with a monkey-pathogenic strain of lymphocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f37c1da7d6faa6ee200398aa4eeab2
https://archive-ouverte.unige.ch/unige:98394
https://archive-ouverte.unige.ch/unige:98394
Autor:
Kevin Larimore, Benedict Fallet, Laura Sironi, Juan Carlos de la Torre, Philip D. Greenberg, Jessica Fioravanti, Pietro Di Lucia, Marta Mainetti, Stefano Sammicheli, Marco De Giovanni, Claudia Cristofani, Mirela Kuka, Renato Ostuni, Carmela G. Maganuco, Lucia Ganzer, Luca G. Guidotti, Nereida Jiménez de Oya, Matteo Iannacone
Publikováno v:
Science Immunology. 1
Antibodies are critical for protection against viral infections. However, several viruses, such as lymphocytic choriomeningitis virus (LCMV), avoid the induction of early protective antibody responses by poorly understood mechanisms. We analyzed the
Autor:
Hanspeter Pircher, Rami Sommerstein, Gert Zimmer, Melissa Remy, Florian Geier, Nicolas Page, Kevin Larimore, Tobias Straub, Daniel D. Pinschewer, Benedict Fallet, Doron Merkler, Kerstin Narr, Karen Cornille, Mario Kreutzfeldt, Yusuf I. Ertuna, Philip D. Greenberg
Publikováno v:
Fallet, Benedict; Narr, Kerstin; Ertuna, Yusuf I; Remy, Melissa; Sommerstein, R.; Cornille, Karen; Kreutzfeldt, Mario; Page, Nicolas; Zimmer, Gert; Geier, Florian; Straub, Tobias; Pircher, Hanspeter; Larimore, Kevin; Greenberg, Philip D; Merkler, Doron; Pinschewer, Daniel D (2016). Interferon-driven deletion of antiviral B cells at the onset of chronic infection. Science immunology, 1(4) American Association for the Advancement of Science 10.1126/sciimmunol.aah6817
Science immunology, Vol. 1, No 4 (2016)
Europe PubMed Central
Sci Immunol
Science Immunology
Science immunology, Vol. 1, No 4 (2016)
Europe PubMed Central
Sci Immunol
Science Immunology
Inadequate antibody responses and perturbed B cell compartments represent hallmarks of persistent microbial infections, but the mechanisms whereby persisting pathogens suppress humoral immunity remain poorly defined. Using adoptive transfer experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8807da23119226a2b8bb0621a05b4fc
https://boris.unibe.ch/96170/1/emss-70441.pdf
https://boris.unibe.ch/96170/1/emss-70441.pdf