Study of the Bcl-2 Interactome by BiFC Reveals Differences in the Activation Mechanism of Bax and Bak.

Autor: Gonzalo, Óscar¹ (AUTHOR), Benedi, Andrea¹ (AUTHOR), Vela, Laura¹ (AUTHOR), Anel, Alberto¹ (AUTHOR), Naval, Javier¹ (AUTHOR), Marzo, Isabel¹ (AUTHOR) imarzo@unizar.es

Publikováno v: Cells (2073-4409). Mar2023, Vol. 12 Issue 5, p800. 23p.

Synthetic ease and exceptional in vivo performance of pyrazole-based cyclometallated iridium complexes.

Autor: Redrado, Marta, Romanos, Eduardo, Benedi, Andrea, Canudo-Barreras, Guillermo, Marzo, Isabel, Gimeno, M. Concepción, Fernández-Moreira, Vanesa

Publikováno v: Inorganic Chemistry Frontiers; 3/21/2024, Vol. 11 Issue 6, p1828-1838, 11p

Multifunctional Heterometallic Ir^III−Au^I Probes as Promising Anticancer and Antiangiogenic Agents.

Autor: Redrado, Marta¹ (AUTHOR), Benedi, Andrea² (AUTHOR), Marzo, Isabel² (AUTHOR), García‐Otín, Angel L.³ (AUTHOR) algarcia.iacs@aragon.es, Fernández‐Moreira, Vanesa¹ (AUTHOR) vanesa@unizar.es, Concepción Gimeno, M.¹ (AUTHOR) gimeno@unizar.es

Publikováno v: Chemistry - A European Journal. 7/7/2021, Vol. 27 Issue 38, p9885-9897. 13p.

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Dinaciclib synergizes with BH3 mimetics targeting BCL-2 and BCL-X L in multiple myeloma cell lines partially dependent on MCL-1 and in plasma cells from patients.

Autor: Beltrán-Visiedo M; Apoptosis, Immunity & Cancer Group, IIS Aragón, University of Zaragoza, Spain., Jiménez-Alduán N; Apoptosis, Immunity & Cancer Group, IIS Aragón, University of Zaragoza, Spain., Díez R; Apoptosis, Immunity & Cancer Group, IIS Aragón, University of Zaragoza, Spain.; Hematology Service, Hospital Universitario Miguel Servet, Zaragoza, Spain., Cuenca M; Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, The Netherlands., Benedi A; Apoptosis, Immunity & Cancer Group, IIS Aragón, University of Zaragoza, Spain., Serrano-Del Valle A; Apoptosis, Immunity & Cancer Group, IIS Aragón, University of Zaragoza, Spain., Azaceta G; Hematology Service, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.; HCU-Lozano Blesa-Hematology Research Group, IIS Aragón, Instituto Aragonés de Ciencias de la Salud, Zaragoza, Spain., Palomera L; Hematology Service, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.; HCU-Lozano Blesa-Hematology Research Group, IIS Aragón, Instituto Aragonés de Ciencias de la Salud, Zaragoza, Spain., Peperzak V; Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, The Netherlands., Anel A; Apoptosis, Immunity & Cancer Group, IIS Aragón, University of Zaragoza, Spain., Naval J; Apoptosis, Immunity & Cancer Group, IIS Aragón, University of Zaragoza, Spain., Marzo I; Apoptosis, Immunity & Cancer Group, IIS Aragón, University of Zaragoza, Spain.

Publikováno v: Molecular oncology [Mol Oncol] 2023 Dec; Vol. 17 (12), pp. 2507-2525. Date of Electronic Publication: 2023 Sep 28.