Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Benedetto Diciaccio"'
Autor:
Bojana Jovanović, Daniel Temko, Laura E. Stevens, Marco Seehawer, Anne Fassl, Katherine Murphy, Jayati Anand, Kodie Garza, Anushree Gulvady, Xintao Qiu, Nicholas W. Harper, Veerle W. Daniels, Huang Xiao-Yun, Jennifer Y. Ge, Maša Alečković, Jason Pyrdol, Kunihiko Hinohara, Shawn B. Egri, Malvina Papanastasiou, Raga Vadhi, Alba Font-Tello, Robert Witwicki, Guillermo Peluffo, Anne Trinh, Shaokun Shu, Benedetto Diciaccio, Muhammad B. Ekram, Ashim Subedee, Zachary T. Herbert, Kai W. Wucherpfennig, Anthony G. Letai, Jacob D. Jaffe, Piotr Sicinski, Myles Brown, Deborah Dillon, Henry W. Long, Franziska Michor, Kornelia Polyak
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113564- (2023)
Summary: Triple-negative breast cancer (TNBC) is a heterogeneous disease with limited treatment options. To characterize TNBC heterogeneity, we defined transcriptional, epigenetic, and metabolic subtypes and subtype-driving super-enhancers and transc
Externí odkaz:
https://doaj.org/article/5b7a46fb42fa443eac6a172b0b60048f
Autor:
Maša Alečković, Simona Cristea, Carlos R. Gil Del Alcazar, Pengze Yan, Lina Ding, Ethan D. Krop, Nicholas W. Harper, Ernesto Rojas Jimenez, Donghao Lu, Anushree C. Gulvady, Pierre Foidart, Marco Seehawer, Benedetto Diciaccio, Katherine C. Murphy, Jason Pyrdol, Jayati Anand, Kodie Garza, Kai W. Wucherpfennig, Rulla M. Tamimi, Franziska Michor, Kornelia Polyak
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
TGFβ signalling is reported to regulate hormone-responsive mammary epithelial progenitors that are associated with breast cancer risk. Here, the authors find that short-term TGFBR1 inhibition prevents tumour formation in rat breast cancer models and
Externí odkaz:
https://doaj.org/article/1cad67a83e124a70947f561786bfe0e4
Autor:
Benedetto DiCiaccio, Evangelia Papachristou, Malvina Papanastasiou, Andrew Reiter, Jason Carroll, Kornelia Polyak
Publikováno v:
Cancer Research. 82:A023-A023
We previously described that the KDM5B histone H3 lysine 4 demethylase is amplified and overexpressed in luminal estrogen receptor positive breast cancer, and its activity is associated with resistance to endocrine therapies. We have found that the K
Publikováno v:
Journal of Clinical Neurophysiology. 33:359-366
INTRODUCTION We report a unique EEG phenomenon in patients with paroxysmal neurological events undergoing video EEG monitoring. METHODS Two epilepsy centers analyzed the interictal scalp EEG in patients using personal electronic devices during epilep
Publikováno v:
Epilepsy & Behavior. 59:117-121
Objective The objective of this study was to report the EEG features of text messaging using smartphones. Methods One hundred twenty-nine patients were prospectively evaluated during video-EEG monitoring (VEM) over 16months. A reproducible texting rh
Autor:
Nurdina Karic, Lee Seifer, Hope Pan, Ahmed S. Elshikha, Brian Brenner, Mohammad Ahsanul Akbar, Sihong Song, Ye Yuan, Benedetto DiCiaccio, Denis Titov, Lei Zhou, Yuanqing Lu, Ying Li
Publikováno v:
Aging Cell
Summary Inflammaging plays an important role in most age‐related diseases. However, the mechanism of inflammaging is largely unknown, and therapeutic control of inflammaging is challenging. Human alpha‐1 antitrypsin (hAAT) has immune‐regulatory
Autor:
Yueming Zhai, Benedetto DiCiaccio, Dong Su, Wenxiao Guo, Dehong Hu, Aaron C. Johnston-Peck, Joseph S. DuChene, Jingjing Qiu, Yi-Chung Wang, Kun Qian, Evan Wenbo Zhao, Frances Ooi, Zihua Zhu, Eric A. Stach, Bo You, Wei David Wei
Publikováno v:
Nature materials. 15(8)
After more than a decade, it is still unknown whether the plasmon-mediated growth of silver nanostructures can be extended to the synthesis of other noble metals, as the molecular mechanisms governing the growth process remain elusive. Herein, we dem
Autor:
Ying Li, Benedetto DiCiaccio, Jessica T. Cheung, Adrian A. Acuna Higaki, Victor T. Lin, Varsha Sundaresan, Nicole F. Pelletier, Lei Zhou
Publikováno v:
Cancer Research. 78:5367-5367
Mutations in tp53 are thought to be one of the most common mechanisms by which cancer cells evade tumor suppression. Yet the exact mechanism of tumor suppression by P53 remains to be fully understood. The transcription factor P53 is activated in resp
Publikováno v:
Cancer Research. 77:391-391
Cancer is considered to be a genetic disease characterized by sequential accumulation of mutations. Recent studies have provided evidence that epigenetic changes and regulatory sequence mutations could also dysregulate oncogenes and tumor suppressors