Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Benedetta Tantini"'
Publikováno v:
Critical reviews in eukaryotic gene expression. 25(1)
Cells adapt their metabolism and activities in response to signals from their surroundings, and this ability is essential for their survival in the face of environmental changes. In mammalian tissues a deficit of these mechanisms is commonly associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d727db10e3e92b546cd6d1ddbb9db2
https://pubmed.ncbi.nlm.nih.gov/25955819
https://pubmed.ncbi.nlm.nih.gov/25955819
Autor:
Silvia Cetrullo, Claudio Stefanelli, Annalisa Facchini, Claudia Pazzini, Flavio Flamigni, Claudio Marcello Caldarera, Benedetta Tantini, Carla Pignatti
Publikováno v:
Nutrients
Nutrients; Volume 4; Issue 2; Pages: 78-90
Nutrients, Vol 4, Iss 2, Pp 78-90 (2012)
Nutrients; Volume 4; Issue 2; Pages: 78-90
Nutrients, Vol 4, Iss 2, Pp 78-90 (2012)
Apoptosis is a programmed cell death that plays a critical role in cell homeostasis. In particular, apoptosis in cardiomyocytes is involved in several cardiovascular diseases including heart failure. Recently autophagy has emerged as an important mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c0a462cf3ec55aaae687fac865ae0d7
https://doi.org/10.3390/nu4020078
https://doi.org/10.3390/nu4020078
Autor:
Emanuele Giordano, Claudio Muscari, Benedetta Tantini, Claudio Stefanelli, Claudio Marcello Caldarera, Flavio Flamigni, Carla Pignatti, Carlo Guarnieri
Publikováno v:
Open Heart Failure Journal. 3:25-30
The natural diamine putrescine and polyamines spermidine and spermine belong to a family of low-molecular- weight organic polycations that are classically known to be important mediators of cell growth, proliferation and division. Several studies are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0daee67b17871d635d22005da0c12ae6
https://doi.org/10.2174/1876535101003020025
https://doi.org/10.2174/1876535101003020025
Autor:
Flavio Flamigni, Ivana Stanic, Silvia Cetrullo, Annalisa Facchini, Benedetta Tantini, Claudio Stefanelli, Rosa Maria Borzì, Carlo Guarnieri, Claudio Marcello Caldarera
Publikováno v:
Journal of Cellular Physiology. 216:153-161
Chondrocyte survival is closely linked to cartilage integrity, and forms of chondrocyte apoptotic death can contribute to cartilage degeneration in articular diseases. Since growing evidence also implicates polyamines in the control of cell death, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085aa8213661ffb46e4ace07cc997fee
https://doi.org/10.1002/jcp.21387
https://doi.org/10.1002/jcp.21387
Autor:
Annalisa Facchini, Manuela Minguzzi, Andrea Facchini, Eleonora Olivotto, Daniela Platano, Serena Guidotti, Ermanno Martucci, Rosa Maria Borzì, Giuseppe Filardo, Flavio Flamigni, Silvia Cetrullo, Giovanni Trisolino, Benedetta Tantini
The molecular mechanisms underlying spermine osteo-inductive activity on human adipose-derived stem cells (ASCs) grown in 3-dimensional (3D) cultures were investigated. Spermine belongs to the polyamine family, naturally occurring, positively charged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551e3967edcc32eb2d5c9029d2fc5191
http://hdl.handle.net/11585/342115
http://hdl.handle.net/11585/342115
Autor:
Benedetta Tantini, Carla Pignatti, Emanuela Fiumana, Angelo Branzi, Alessandra Manes, Carlo Guarnieri, Nazzareno Galiè, Romano Zannoli
Publikováno v:
Basic Research in Cardiology. 100:131-138
Pulmonary arterial hypertension (PAH) is characterized by vasoconstriction and by obstructive changes of the pulmonary vasculature including smooth muscle cell proliferation which leads to medial hypertrophy and subsequent luminal narrowing. Sildenaf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860a85379a755b653d98c4733692ac32
https://doi.org/10.1007/s00395-004-0504-5
https://doi.org/10.1007/s00395-004-0504-5
Publikováno v:
Amino Acids. 27:359-365
Polyamines are important multifunctional cellular components and are classically considered as mediators of cell growth and division. Recently polyamines have been also implicated in cell death. Now it appears that polyamines are bivalent regulators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d7702e8dc31edbd026bd2e37695e6e
https://doi.org/10.1007/s00726-004-0115-3
https://doi.org/10.1007/s00726-004-0115-3
Autor:
Caroline A. Mackintosh, Claudio Marcello Caldarera, C. Clô, Claudio Stefanelli, Flavio Flamigni, Benedetta Tantini, Anthony E. Pegg, Carlo Guarnieri, Ivana Stanic, Carla Pignatti, Monia Fattori
Publikováno v:
FEBS Letters. 527:223-228
Activation of the extracellular signal-regulated kinases (ERKs) 1 and 2 is correlated to cell survival, but in some cases ERKs can act in signal transduction pathways leading to apoptosis. Treatment of mouse fibroblasts with 20 microM etoposide elici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23fa40e541aa79d623374f1ac471674a
https://doi.org/10.1016/s0014-5793(02)03242-8
https://doi.org/10.1016/s0014-5793(02)03242-8
Autor:
Francesca Bonavita, Ivana Stanic, Benedetta Tantini, Annalisa Facchini, Flavio Flamigni, Claudio Stefanelli
Publikováno v:
Biochemical Pharmacology. 62:319-328
Intracellular signaling pathways involved in the survival of proliferating L1210 leukemia cells were investigated by using specific modulators. Among the various inhibitors tested, only 1H-[1,2,4]oxadiazole [4,3-a]quinoxalin-1-one (ODQ), a soluble gu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::119ff5825edff5264234a6480b660499
https://doi.org/10.1016/s0006-2952(01)00646-3
https://doi.org/10.1016/s0006-2952(01)00646-3
Autor:
Claudio STEFANELLI, Carla PIGNATTI, Benedetta TANTINI, Monia FATTORI, Ivana STANIC, Caroline A. MACKINTOSH, Flavio FLAMIGNI, Carlo GUARNIERI, Claudio M. CALDARERA, Anthony E. PEGG
Publikováno v:
Biochemical Journal. 355:199-206
Activation of the caspase proteases represents a central point in apoptosis. The requirement for spermine for the processes leading to caspase activation has been studied in transformed embryonic fibroblasts obtained from gyro (Gy) mutant male mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0710346a90ac482c1ee38c07371e58fb
https://doi.org/10.1042/bj3550199
https://doi.org/10.1042/bj3550199