Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Benedetta Gualeni"'
Autor:
Benedetta Gualeni, Frider Chimimba, Ibrahim Chikowe, Isabelle Stauber, Louise Hughes, Angela Gorman, Louise Ackers, Nettie Dzabala, Dorothy Gashuga, James C. Birchall, Sion A. Coulman
Publikováno v:
Gates Open Research, Vol 5 (2021)
Background: It is estimated that 225 million women worldwide have an unmet need for family planning, and more than half live in low- and middle-income countries. Increasing the choice of contraceptive methods available can reduce this unmet need. Mic
Externí odkaz:
https://doaj.org/article/ef68a0f9687e4e939e4b88590f9df7e1
Autor:
Benedetta Gualeni, M. Helen Rajpar, Aaron Kellogg, Peter A. Bell, Peter Arvan, Raymond P. Boot-Handford, Michael D. Briggs
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 6, Pp 1414-1425 (2013)
SUMMARY Disease mechanisms leading to different forms of chondrodysplasia include extracellular matrix (ECM) alterations and intracellular stress resulting in abnormal changes to chondrocyte proliferation and survival. Delineating the relative contri
Externí odkaz:
https://doaj.org/article/3ea52079ed074c5f94274bc43ec6b790
Publikováno v:
Drug Delivery and Translational Research
Microneedle (MN)-based technologies have been proposed as a means to facilitate minimally invasive sustained delivery of long-acting hormonal contraceptives into the skin. Intradermal administration is a new route of delivery for these contraceptives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::599ba6201b5d0559c6827c23890c79fb
http://europepmc.org/articles/PMC8724103
http://europepmc.org/articles/PMC8724103
Autor:
Huma Ashraf, Chris Bolton, Pey F. Eng, Gareth J. Blayney, Kerry Roberts, Owen J. Guy, Benedetta Gualeni, James Caradoc Birchall, Olivia Howells
Publikováno v:
Lab on a chip. 20(15)
A novel production process flow is presented here for the manufacture of hollow silicon microneedles using deep reactive-ion etching (DRIE) technology. The patent-pending three-step process flow has been developed to produce multiple arrays of sharp-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c56f80e0f6e12167c646a0b86b1f75
https://pubmed.ncbi.nlm.nih.gov/32632424
https://pubmed.ncbi.nlm.nih.gov/32632424
Autor:
Nettie Dzabala, Dorothy Gashuga, Benedetta Gualeni, Louise Ackers, James Caradoc Birchall, Angela Gorman, Sion Coulman, Louise Hughes, Isabelle Stauber
Publikováno v:
Gates Open Research. 5:96
Background: It is estimated that 225 million women worldwide have an unmet need for family planning, and more than half live in low- and middle-income countries. Increasing the choice of contraceptive methods available can reduce this unmet need. Mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc1ec4f45ff04c4b7e68098994952b3
https://doi.org/10.12688/gatesopenres.13233.1
https://doi.org/10.12688/gatesopenres.13233.1
Autor:
Sion Coulman, Gareth J. Blayney, Huma Ashraf, P.F. Eng, James Caradoc Birchall, Dilip Shah, Owen J. Guy, P. Vescovo, L.-D. Piveteau, Benedetta Gualeni
Background Translation of cell therapies to the clinic is accompanied by numerous challenges, including controlled and targeted delivery of the cells to their site of action, without compromising cell viability and functionality. Objectives To explor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193f852023e8badd51729d01bfca97f5
https://cronfa.swan.ac.uk/Record/cronfa50743
https://cronfa.swan.ac.uk/Record/cronfa50743
Autor:
Luca Monti, Antonio Rossi, Benedetta Gualeni, Antonella Forlino, Fabio De Leonardis, Ruggero Tenni
Publikováno v:
Journal of Cellular Biochemistry
In several skeletal dysplasias defects in extracellular matrix molecules affect not only the structural and mechanical properties of cartilage, but also the complex network of signaling pathways involved in cell proliferation and differentiation. Sul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9766518b54e2a891fa8600050bd10a78
https://doi.org/10.1002/jcb.24844
https://doi.org/10.1002/jcb.24844
Autor:
Peter Arvan, Benedetta Gualeni, M. Helen Rajpar, Michael D. Briggs, Aaron P. Kellogg, Raymond P. Boot-Handford, Peter A. Bell
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 6, Pp 1414-1425 (2013)
Disease Models & Mechanisms
Disease Models & Mechanisms
SummaryDisease mechanisms leading to different forms of chondrodysplasia include extracellular matrix (ECM) alterations and intracellular stress resulting in abnormal changes to chondrocyte proliferation and survival. Delineating the relative contrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35727309304ca3b71213905fb763e9d0
http://dmm.biologists.org/content/6/6/1414
http://dmm.biologists.org/content/6/6/1414
Autor:
Katarzyna A. Piróg, Paul Holden, Benedetta Gualeni, Hannah J Gregson, Farhana Suleman, Matthew Leighton, Sarah M. Edwards, Raymond P. Boot-Handford, Michael D. Briggs
Publikováno v:
Human Mutation
Pseudoachondroplasia (PSACH) results from mutations in cartilage oligomeric matrix protein (COMP) and the p.D469del mutation within the type III repeats of COMP accounts for approximately 30% of PSACH. To determine disease mechanisms of PSACH in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52cbb09ef75e20f747cbf6b79a5a38f7
https://doi.org/10.1002/humu.21631
https://doi.org/10.1002/humu.21631
Autor:
Chiara Tani, Antonio Rossi, Anna Lupi, Luca Bini, Benedetta Gualeni, Antonella Forlino, Giuseppe Cetta, Elena Campari, Alessandro Armini, Laura Bianchi, Joan C. Marini
Publikováno v:
PROTEOMICS. 7:1877-1891
This study used proteomic and transcriptomic techniques to understand the molecular basis of the phenotypic variability in the bone disorder osteogenesis imperfecta (OI). Calvarial bone mRNA expression was evaluated by microarray, real-time, and comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493d9a5b0461eff204d8765e8718aede
https://doi.org/10.1002/pmic.200600919
https://doi.org/10.1002/pmic.200600919