Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bendsen, Jacob"'
Autor:
Blicher, Laura Hjort, Carstensen, Peter Emil, Bendsen, Jacob, Linden, Henrik, Hald, Bjørn, Kristensen, Kim, Jørgensen, John Bagterp
Physiological whole-body models are valuable tools for the development of novel drugs where understanding the system aspects is important. This paper presents a generalized model that encapsulates the structure and flow of whole-body human physiology
Externí odkaz:
http://arxiv.org/abs/2404.14224
Autor:
Carstensen, Peter Emil, Bendsen, Jacob, Blicher, Laura Hjort, Kristensen, Kim, Jørgensen, John Bagterp
Cardiovascular diseases are the leading cause of death. Increased levels of plasma cholesterol are consistently associated with an increased risk of cardiovascular disease. As a result, it is imperative that studies are conducted to determine the bes
Externí odkaz:
http://arxiv.org/abs/2404.13934
Autor:
Ritschel, Tobias K. S., Reenberg, Asbjørn Thode, Carstensen, Peter Emil, Bendsen, Jacob, Jørgensen, John Bagterp
We present and critically discuss five commonly used mathematical models of the meal glucose rate of appearance in humans. Such models are key to simulation of the metabolism in healthy people, people with diabetes, and obese people, and they are cen
Externí odkaz:
http://arxiv.org/abs/2307.16444
Autor:
Bendsen, Jacob, Carstensen, Peter Emil, Reenberg, Asbjørn Thode, Ritschel, Tobias K. S., Jørgensen, John Bagterp
We present a whole-body model of human metabolism that utilizes a system of organs and blood vessels to simulate the enzymatic reactions. The model focuses on key organs, including the brain, heart and lungs, liver, gut, and kidney, as well as muscle
Externí odkaz:
http://arxiv.org/abs/2307.16167
Autor:
Carstensen, Peter Emil, Bendsen, Jacob, Reenberg, Asbjørn Thode, Ritschel, Tobias K. S., Jørgensen, John Bagterp
We propose a whole-body model of the metabolism in man as well as a generalized approach for modeling metabolic networks. Using this approach, we are able to write a large metabolic network in a systematic and compact way. We demonstrate the approach
Externí odkaz:
http://arxiv.org/abs/2205.01473