Detection and analysis of complex structural variation in human genomes across populations and in brains of donors with psychiatric disorders.

Autor: Zhou B; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA; Maternal and Child Health Research Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: bozhou@alumni.stanford.edu., Arthur JG; Department of Statistics, Stanford University, Stanford, CA 94305, USA., Guo H; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA; Maternal and Child Health Research Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Statistics, Stanford University, Stanford, CA 94305, USA; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA., Kim T; School of Computer Science and Engineering, Pusan National University, Busan 46241, South Korea., Huang Y; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Pattni R; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Wang T; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Kundu S; Department of Genetics, Stanford University, Stanford, CA 94305, USA; Department of Computer Science, Stanford University, Stanford, CA 94305, USA., Luo JXJ; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Lee H; Division of Oncology, Department of Medicine, Stanford University, Stanford, CA 94305, USA., Nachun DC; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Purmann C; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA; Maternal and Child Health Research Institute, Stanford University School of Medicine, Stanford, CA 94305, USA., Monte EM; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Weimer AK; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Qu PP; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Shi M; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Jiang L; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Yang X; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Fullard JF; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Bendl J; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Girdhar K; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Kim M; School of Computer Science and Engineering, Pusan National University, Busan 46241, South Korea., Chen X; Department of Statistics, Stanford University, Stanford, CA 94305, USA; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA., Greenleaf WJ; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Duncan L; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA., Ji HP; Division of Oncology, Department of Medicine, Stanford University, Stanford, CA 94305, USA., Zhu X; Department of Statistics, Stanford University, Stanford, CA 94305, USA; Department of Statistics, Pennsylvania State University, University Park, PA 16802, USA; Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA., Song G; School of Computer Science and Engineering, Pusan National University, Busan 46241, South Korea; Center for Artificial Intelligence Research, Pusan National University, Busan 46241, South Korea., Montgomery SB; Department of Genetics, Stanford University, Stanford, CA 94305, USA; Maternal and Child Health Research Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Palejev D; Institute of Mathematics and Informatics, Bulgarian Academy of Sciences, Sofia 1113, Bulgaria., Zu Dohna H; Department of Biology, American University of Beirut, Beirut 11-0236, Lebanon., Roussos P; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Center for Precision Medicine and Translational Therapeutics, James J. Peters VA Medical Center, Bronx, NY 10468, USA; Mental Illness Research Education and Clinical Center (VISN 2 South), James J. Peters VA Medical Center, Bronx, NY 10468, USA., Kundaje A; Department of Genetics, Stanford University, Stanford, CA 94305, USA; Department of Computer Science, Stanford University, Stanford, CA 94305, USA., Hallmayer JF; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA., Snyder MP; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Wong WH; Department of Statistics, Stanford University, Stanford, CA 94305, USA; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA. Electronic address: whwong@stanford.edu., Urban AE; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA; Maternal and Child Health Research Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: aeurban@stanford.edu.

Publikováno v: Cell [Cell] 2024 Sep 28. Date of Electronic Publication: 2024 Sep 28.

Single cell transcriptomes and multiscale networks from persons with and without Alzheimer's disease.

Autor: Wang Q; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, AZ, 85281, USA., Antone J; Division of Neurogenomics, The Translational Genomics Research Institute, Phoenix, AZ, 85004, USA., Alsop E; Division of Neurogenomics, The Translational Genomics Research Institute, Phoenix, AZ, 85004, USA., Reiman R; Division of Neurogenomics, The Translational Genomics Research Institute, Phoenix, AZ, 85004, USA., Funk C; Institute for Systems Biology, Seattle, WA, 98109, USA., Bendl J; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Dudley JT; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, AZ, 85281, USA., Liang WS; Division of Neurogenomics, The Translational Genomics Research Institute, Phoenix, AZ, 85004, USA., Karr TL; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, AZ, 85281, USA., Roussos P; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, 60612, USA., De Jager PL; Department of Neurology, Center for Translational and Computational Neuroimmunology, Columbia University Irving Medical Center, New York, NY, 10032, USA., Serrano GE; Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Sun City, AZ, 85351, USA., Beach TG; Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Sun City, AZ, 85351, USA., Van Keuren-Jensen K; Division of Neurogenomics, The Translational Genomics Research Institute, Phoenix, AZ, 85004, USA., Mastroeni D; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, AZ, 85281, USA., Reiman EM; Banner Alzheimer's Institute, Phoenix, AZ, 85006, USA., Readhead BP; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, AZ, 85281, USA. ben.readhead@asu.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Jul 10; Vol. 15 (1), pp. 5815. Date of Electronic Publication: 2024 Jul 10.

Genetic regulation of cell type-specific chromatin accessibility shapes brain disease etiology.

Autor: Zeng B; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Bendl J; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Deng C; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158, USA.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94158, USA., Lee D; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Misir R; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Reach SM; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Kleopoulos SP; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Auluck P; Human Brain Collection Core, National Institute of Mental Health-Intramural Research Program, Bethesda, MD 20892, USA., Marenco S; Human Brain Collection Core, National Institute of Mental Health-Intramural Research Program, Bethesda, MD 20892, USA., Lewis DA; Translational Neuroscience Program, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Haroutunian V; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Mental Illness Research, Education and Clinical Centers, James J. Peters VA Medical Center, Bronx, NY 10468, USA., Ahituv N; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158, USA.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94158, USA., Fullard JF; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Hoffman GE; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Roussos P; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Mental Illness Research, Education and Clinical Centers, James J. Peters VA Medical Center, Bronx, NY 10468, USA.

Publikováno v: Science (New York, N.Y.) [Science] 2024 May 24; Vol. 384 (6698), pp. eadh4265. Date of Electronic Publication: 2024 May 24.

Single-cell genomics and regulatory networks for 388 human brains.

Autor: Emani PS; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Liu JJ; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Clarke D; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Jensen M; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Warrell J; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Gupta C; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53706, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA., Meng R; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Lee CY; Department of Computer Science, University of California, Irvine, CA 92697, USA., Xu S; Department of Computer Science, University of California, Irvine, CA 92697, USA., Dursun C; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Lou S; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Chen Y; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Chu Z; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA., Galeev T; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Hwang A; Department of Computer Science, University of California, Irvine, CA 92697, USA.; Mathematical, Computational and Systems Biology, University of California, Irvine, CA 92697, USA., Li Y; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.; Department of Computer Science, Yale University, New Haven, CT 06520, USA., Ni P; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Zhou X; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Bakken TE; Allen Institute for Brain Science, Seattle, WA 98109, USA., Bendl J; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Bicks L; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Chatterjee T; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Cheng L; Tempus Labs, Chicago, IL 60654, USA., Cheng Y; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.; Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Dai Y; Department of Computer Science, University of California, Irvine, CA 92697, USA., Duan Z; Department of Computer Science, University of California, Irvine, CA 92697, USA., Flaherty M; Tempus Labs, Chicago, IL 60654, USA., Fullard JF; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Gancz M; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Garrido-Martín D; Department of Genetics, Microbiology and Statistics, Universitat de Barcelona, Barcelona 08028, Spain., Gaynor-Gillett S; Tempus Labs, Chicago, IL 60654, USA.; Department of Biology, Cornell College, Mount Vernon, IA 52314, USA., Grundman J; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Hawken N; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Henry E; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Hoffman GE; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Mental Illness Research Education and Clinical Center, James J. Peters VA Medical Center, Bronx, NY 10468, USA.; Center for Precision Medicine and Translational Therapeutics, James J. Peters VA Medical Center, Bronx, NY 10468, USA., Huang A; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA., Jiang Y; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Jin T; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53706, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA., Jorstad NL; Allen Institute for Brain Science, Seattle, WA 98109, USA., Kawaguchi R; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.; Center for Autism Research and Treatment, Semel Institute, University of California, Los Angeles, CA 90095, USA., Khullar S; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53706, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA., Liu J; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Liu J; Department of Computer Science, University of California, Irvine, CA 92697, USA., Liu S; Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA., Ma S; Department of Neuroscience, Yale University, New Haven, CT 06510, USA.; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China., Margolis M, Mazariegos S; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Moore J; Department of Genomics and Computational Biology, UMass Chan Medical School, Worcester, MA 01605, USA., Moran JR; Tempus Labs, Chicago, IL 60654, USA., Nguyen E; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Phalke N; Department of Genomics and Computational Biology, UMass Chan Medical School, Worcester, MA 01605, USA., Pjanic M; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Pratt H; Department of Genomics and Computational Biology, UMass Chan Medical School, Worcester, MA 01605, USA., Quintero D; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Rajagopalan AS; Department of Computer Science, Yale University, New Haven, CT 06520, USA., Riesenmy TR; Department of Statistics and Data Science, Yale University, New Haven, CT 06520, USA., Shedd N; Department of Genomics and Computational Biology, UMass Chan Medical School, Worcester, MA 01605, USA., Shi M; Tempus Labs, Chicago, IL 60654, USA., Spector M; Tempus Labs, Chicago, IL 60654, USA., Terwilliger R; Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06520, USA., Travaglini KJ; Allen Institute for Brain Science, Seattle, WA 98109, USA., Wamsley B; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Wang G; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Xia Y; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Xiao S; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Yang AC; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Zheng S; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA., Gandal MJ; Interdepartmental Program in Bioinformatics, University of California, Los Angeles, Los Angeles CA, 90095, USA.; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Lifespan Brain Institute, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Lee D; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Lein ES; Allen Institute for Brain Science, Seattle, WA 98109, USA.; Department of Neurological Surgery, University of Washington, Seattle, WA 98195, USA.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195, USA., Roussos P; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Mental Illness Research Education and Clinical Center, James J. Peters VA Medical Center, Bronx, NY 10468, USA.; Center for Precision Medicine and Translational Therapeutics, James J. Peters VA Medical Center, Bronx, NY 10468, USA., Sestan N; Department of Neuroscience, Yale University, New Haven, CT 06510, USA., Weng Z; Department of Genomics and Computational Biology, UMass Chan Medical School, Worcester, MA 01605, USA., White KP; Yong Loo Lin School of Medicine, National University of Singapore, 117597 Singapore., Won H; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Girgenti MJ; Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06520, USA.; Wu Tsai Institute, Yale University, New Haven, CT 06520, USA.; Clinical Neuroscience Division, National Center for Posttraumatic Stress Disorder, Veterans Affairs Connecticut Healthcare System, West Haven, CT 06516, USA., Zhang J; Department of Computer Science, University of California, Irvine, CA 92697, USA., Wang D; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53706, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA.; Department of Computer Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA., Geschwind D; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.; Center for Autism Research and Treatment, Semel Institute, University of California, Los Angeles, CA 90095, USA.; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Institute for Precision Health, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Gerstein M; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.; Department of Computer Science, Yale University, New Haven, CT 06520, USA.; Department of Statistics and Data Science, Yale University, New Haven, CT 06520, USA.; Department of Biomedical Informatics & Data Science, Yale University, New Haven, CT 06520, USA.

Publikováno v: Science (New York, N.Y.) [Science] 2024 May 24; Vol. 384 (6698), pp. eadi5199. Date of Electronic Publication: 2024 May 24.

Automated SEM/EDX imaging for the in-depth characterization of non-exhaust traffic emissions from the Munich subway system.

Autor: Neukirchen C; University of the Bundeswehr Munich, Faculty for Mechanical Engineering, Institute of Chemical and Environmental Engineering, Werner-Heisenberg-Weg 39, 85577 Neubiberg, Germany; Joint Mass Spectrometry Center (JMSC) at Chair of Analytical Chemistry, Institute of Chemistry, University of Rostock, Albert-Einstein-Strasse 27, 18059 Rostock, Germany., Meiners T; Oxford Instruments GmbH, Borsigstraße 15 A, 652025 Wiesbaden, Germany., Bendl J; University of the Bundeswehr Munich, Faculty for Mechanical Engineering, Institute of Chemical and Environmental Engineering, Werner-Heisenberg-Weg 39, 85577 Neubiberg, Germany; Institute for Environmental Studies, Faculty of Science, Charles University, Benátská 2, 128 01 Prague, Czech Republic. Electronic address: jan.bendl@unibw.de., Zimmermann R; Joint Mass Spectrometry Center (JMSC) at Comprehensive Molecular Analytics (CMA), Department Environmental Health, Helmholtz Munich, Gmunder Str. 37, 81379 München, Germany; Joint Mass Spectrometry Center (JMSC) at Chair of Analytical Chemistry, Institute of Chemistry, University of Rostock, Albert-Einstein-Strasse 27, 18059 Rostock, Germany., Adam T; University of the Bundeswehr Munich, Faculty for Mechanical Engineering, Institute of Chemical and Environmental Engineering, Werner-Heisenberg-Weg 39, 85577 Neubiberg, Germany; Joint Mass Spectrometry Center (JMSC) at Comprehensive Molecular Analytics (CMA), Department Environmental Health, Helmholtz Munich, Gmunder Str. 37, 81379 München, Germany.

Publikováno v: The Science of the total environment [Sci Total Environ] 2024 Mar 10; Vol. 915, pp. 170008. Date of Electronic Publication: 2024 Jan 12.