Alginate microbeads and hydrogels delivering meropenem and bacteriophages to treat Pseudomonas aeruginosa fracture-related infections.

Autor: Chen B; Department of Trauma Surgery, University Hospitals Leuven, Leuven, Belgium; Department of Development and Regeneration, KU Leuven, Leuven, Belgium; AO Research Institute Davos, Davos, Switzerland., Benavente LP; Center for Musculoskeletal Surgery Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany., Chittò M; AO Research Institute Davos, Davos, Switzerland., Wychowaniec JK; AO Research Institute Davos, Davos, Switzerland., Post V; AO Research Institute Davos, Davos, Switzerland., D'Este M; AO Research Institute Davos, Davos, Switzerland., Constant C; AO Research Institute Davos, Davos, Switzerland., Zeiter S; AO Research Institute Davos, Davos, Switzerland., Feng W; AO Research Institute Davos, Davos, Switzerland., Moreno MG; Center for Musculoskeletal Surgery Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany., Trampuz A; Center for Musculoskeletal Surgery Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany., Wagemans J; Laboratory of Gene Technology, KU Leuven, Leuven, Belgium., Onsea J; Department of Trauma Surgery, University Hospitals Leuven, Leuven, Belgium; Department of Development and Regeneration, KU Leuven, Leuven, Belgium., Richards RG; AO Research Institute Davos, Davos, Switzerland., Lavigne R; Laboratory of Gene Technology, KU Leuven, Leuven, Belgium., Moriarty TF; AO Research Institute Davos, Davos, Switzerland. Electronic address: fintan.moriarty@aofoundation.org., Metsemakers WJ; Department of Trauma Surgery, University Hospitals Leuven, Leuven, Belgium; Department of Development and Regeneration, KU Leuven, Leuven, Belgium.

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2023 Dec; Vol. 364, pp. 159-173. Date of Electronic Publication: 2023 Oct 31.