Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Benaglio P"'
Publikováno v:
Formare, Vol 24, Iss 2 (2024)
Adult education today presents new challenges, especially for the caring professions. Although updating knowledge and skills is crucial in these professions to ensure the health of citizens, continuing education that promotes development and self-car
Externí odkaz:
https://doaj.org/article/1bbb8ad067c647e7b884500aea3a1693
Autor:
Paola Benaglio, Jacklyn Newsome, Jee Yun Han, Joshua Chiou, Anthony Aylward, Sierra Corban, Michael Miller, Mei-Lin Okino, Jaspreet Kaur, Sebastian Preissl, David U Gorkin, Kyle J Gaulton
Publikováno v:
PLoS Genetics, Vol 19, Iss 6, p e1010759 (2023)
Gene regulation is highly cell type-specific and understanding the function of non-coding genetic variants associated with complex traits requires molecular phenotyping at cell type resolution. In this study we performed single nucleus ATAC-seq (snAT
Externí odkaz:
https://doaj.org/article/8f67632a3ee14f0184079c1b5f137129
Autor:
Christian Secchi, Paola Benaglio, Francesca Mulas, Martina Belli, Dwayne Stupack, Shunichi Shimasaki
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Adult granulosa cell tumor (aGCT) is a rare type of stromal cell malignant cancer of the ovary characterized by elevated estrogen levels. aGCTs ubiquitously harbor a somatic mutation in FOXL2 gene, Cys134Trp (c.402C
Externí odkaz:
https://doaj.org/article/f4ffe7374cf34a4cb371c47ac367ae69
Akademický článek
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Akademický článek
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Autor:
Erin N. Smith, Agnieszka D'Antonio-Chronowska, William W. Greenwald, Victor Borja, Lana R. Aguiar, Robert Pogue, Hiroko Matsui, Paola Benaglio, Shyamanga Borooah, Matteo D'Antonio, Radha Ayyagari, Kelly A. Frazer
Publikováno v:
Stem Cell Reports, Vol 12, Iss 6, Pp 1342-1353 (2019)
Summary: We evaluate whether human induced pluripotent stem cell-derived retinal pigment epithelium (iPSC-RPE) cells can be used to prioritize and functionally characterize causal variants at age-related macular degeneration (AMD) risk loci. We gener
Externí odkaz:
https://doaj.org/article/9c34a3ce8fe74c1c8d965a279b15f664
Autor:
William W. Greenwald, He Li, Paola Benaglio, David Jakubosky, Hiroko Matsui, Anthony Schmitt, Siddarth Selvaraj, Matteo D’Antonio, Agnieszka D’Antonio-Chronowska, Erin N. Smith, Kelly A. Frazer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
It is currently unclear how quantitative changes in chromatin loop propensity contribute to differential gene regulation. Here, the authors use phased Hi-C, RNA-seq, and ChIP-seq to show that subtle changes in loop propensity associate with different
Externí odkaz:
https://doaj.org/article/f72b1213a233451aa67b2d6cb89c60be
Autor:
Anthony Aylward, Mei-Lin Okino, Paola Benaglio, Joshua Chiou, Elisha Beebe, Jose Andres Padilla, Sharlene Diep, Kyle J Gaulton
Publikováno v:
PLoS Genetics, Vol 17, Iss 5, p e1009531 (2021)
Glucocorticoids are key regulators of glucose homeostasis and pancreatic islet function, but the gene regulatory programs driving responses to glucocorticoid signaling in islets and the contribution of these programs to diabetes risk are unknown. In
Externí odkaz:
https://doaj.org/article/518be40ed7d04e5f8f26f2da3a1882b9
Akademický článek
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Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-6 (2017)
Abstract Background Genomic interaction studies use next-generation sequencing (NGS) to examine the interactions between two loci on the genome, with subsequent bioinformatics analyses typically including annotation, intersection, and merging of data
Externí odkaz:
https://doaj.org/article/2875d9d2c1e943b89db17a505d6b784f