Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ben-Wen Cui"'
Autor:
Jian Liu, Min Jiang, Quan Jin, Yan-Ling Wu, Zhen-Yu Cui, Ben-Wen Cui, Yue Shang, Zi-Ying Zhan, Yong-Ce Lin, Jing-Ya Jiao, Mei-Hua Piao, Zhi-Hong Zhang, Rong-Hui Sun, Ji-Xing Nan, Li-Hua Lian
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Acetaminophen (APAP), one of the most common antipyretic analgesics, which is safe at therapeutic dose, cause acute liver injury and even death at overdose. However, the mechanism of APAP-induced inflammation in liver injury is still controversial. T
Externí odkaz:
https://doaj.org/article/f71fc6310cc24e7bb0bcc1e4bf999dd0
Autor:
Huan Ye, Hong-Xu Yang, Yu Zhang, Ji-Xing Nan, Jian Liu, Chun-Ying Qiao, Zi-Ying Zhan, Min Jiang, Ben-Wen Cui, Yue Shang, Yan-Ling Wu, Li-Hua Lian, Quan Jin
Publikováno v:
Toxicology Letters. 333:22-32
HSCs (hepatic stellate cells) contribute to the excessive extracellular matrix (ECM) deposition, inflammatory pathways and crucial cell-cell interactions in hepatic disease leading to fibrosis. P2x7R is considered a potential orchestrater in liver fi
Autor:
Ji-Xing Nan, Yu Zhang, Hong-Xu Yang, Ting Bai, Chun-Ying Qiao, Zi-Ying Zhan, Jian Liu, Ben-Wen Cui, Dong-Zhou Kang, Li-Hua Lian, Min Jiang, Mei Wu, Yan-Ling Wu, Yong Yang
Publikováno v:
The American Journal of Chinese Medicine. 47:577-594
Thymoquinone (TQ) is a main aromatic component of Nigella sativa L. seeds or Agastache rugosa (Fisch. & C.A.Mey.) Kuntze. The protective mechanism of TQ against acute liver injury induced by acetaminophen (APAP), however, remains unclear. We aimed to
Autor:
Kai-Li Xia, Xia Li, Min Jiang, Quan Jin, Shun-Zong Song, Ben-Wen Cui, Yan-Ling Wu, Li-Hua Lian, Yu Zhang, Ji-Xing Nan
Publikováno v:
British Journal of Pharmacology. 175:1451-1470
BACKGROUND AND PURPOSE Regulating P2X7 receptor-mediated activation of NLRP3 inflammasomes could be a therapeutic strategy to treat alcoholic hepatosteatosis. We investigated whether this process was modulated by gentiopicroside, the main active seco
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO4-8
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO1-9
Autor:
Yu Zhang, Guang-Hao Zheng, Quan Jin, Zi-Ying Zhan, Ji-Xing Nan, Chun-Ying Qiao, Yan-Ling Wu, Huan Ye, Hong-Xu Yang, Cheng Hua Jin, Jian Liu, Ben-Wen Cui, Li-Hua Lian, Yue Shang, Min Jiang, Mei Wu
Publikováno v:
Br J Pharmacol
Background and purpose Regulating macrophage-hepatocyte crosstalk through P2X7 receptors has led to new pharmacological strategies to reverse alcoholic hepatosteatosis. We investigated how tetrahydroxystilbene glucoside (2354glu), isolated from Polyg
Autor:
Hong-Xu Yang, Quan Jin, Min Jiang, Mei Wu, Xia Li, Yue Shang, Ji-Xing Nan, Yu Zhang, Jian Liu, Cheng-Min Jin, Li-Hua Lian, Ying Li, Yan-Ling Wu, Ben-Wen Cui, Ming-Ji Jin
Publikováno v:
Journal of agricultural and food chemistry. 66(50)
Pleurotus citrinopileatus (golden oyster mushroom) is a widely used edible mushroom. We investigated the inhibitory effect of P. citrinopileatus aqueous extract against alcoholic steatohepatitis and its underlying mechanism. Acute and chronic ethanol
Publikováno v:
Journal of Ethnopharmacology. 264:113391
Ethnopharmacological relevance As the largest genus of Gentianaceae family, the Gentiana genus harbors over 400 species, widely distributed in the alpine areas of temperate regions worldwide. Plants from Gentiana genus are traditionally used to treat
Autor:
Ji-Xing Nan, Min Jiang, Ming-Ji Jin, Quan Jin, Li-Hua Lian, Yu Zhang, Xia Li, Yue Shang, Ying Li, Li Xifeng, Yan-Ling Wu, Ben-Wen Cui
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 107
The current study was aimed to reveal that leucodin, a sesquiterpene lactone from Artemisia capillaris could inhibit the inflammatory response in macrophages and the lipid accumulation in hepatocytes via P2x7R-NLRP3 inflammasome activation. Several t