Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Ben-Gary Harvey"'
Autor:
Guoqing Wang, Rui Wang, Yael Strulovici-Barel, Jacqueline Salit, Michelle R Staudt, Joumana Ahmed, Ann E Tilley, Jenny Yee-Levin, Charleen Hollmann, Ben-Gary Harvey, Robert J Kaner, Jason G Mezey, Sriram Sridhar, Sreekumar G Pillai, Holly Hilton, Gerhard Wolff, Hans Bitter, Sudha Visvanathan, Jay S Fine, Christopher S Stevenson, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0120824 (2015)
Even after quitting smoking, the risk of the development of chronic obstructive pulmonary disease (COPD) and lung cancer remains significantly higher compared to healthy nonsmokers. Based on the knowledge that COPD and most lung cancers start in the
Externí odkaz:
https://doaj.org/article/1b6f44e9a64d47daab4df117cf0df208
Autor:
Justina Hessel, Jonna Heldrich, Jennifer Fuller, Michelle R Staudt, Sharon Radisch, Charleen Hollmann, Ben-Gary Harvey, Robert J Kaner, Jacqueline Salit, Jenny Yee-Levin, Sriram Sridhar, Sreekumar Pillai, Holly Hilton, Gerhard Wolff, Hans Bitter, Sudha Visvanathan, Jay Fine, Christopher S Stevenson, Ronald G Crystal, Ann E Tilley
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85453 (2014)
Smoking and COPD are associated with decreased mucociliary clearance, and healthy smokers have shorter cilia in the large airway than nonsmokers. We hypothesized that changes in cilia length are consistent throughout the airway, and we further hypoth
Externí odkaz:
https://doaj.org/article/920a4ce070f54f71b8b709ce5d214c3e
Autor:
Ben-Gary Harvey, Yael Strulovici-Barel, Thomas L Vincent, Jason G Mezey, Ramya Raviram, Cynthia Gordon, Jacqueline Salit, Ann E Tilley, Augustine Chung, Abraham Sanders, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72669 (2013)
The distribution of lung disease induced by inhaled cigarette smoke is complex, depending on many factors. With the knowledge that the small airway epithelium (SAE) is the earliest site of smoking-induced lung disease, and that the SAE gene expressio
Externí odkaz:
https://doaj.org/article/aa04e3b9047f4ec39a2834a45205af10
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11004 (2010)
The inflammatory milieu in the respiratory tract in cystic fibrosis (CF) has been linked to the defective expression of the cystic transmembrane regulator (CFTR) in epithelial cells. Alveolar macrophages (AM), important contibutors to inflammatory re
Externí odkaz:
https://doaj.org/article/9d634fecd80c41739068f3cfb28a0339
Autor:
Philip L Leopold, Michael J O'Mahony, X Julie Lian, Ann E Tilley, Ben-Gary Harvey, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8157 (2009)
BACKGROUND:Whereas cilia damage and reduced cilia beat frequency have been implicated as causative of reduced mucociliary clearance in smokers, theoretically mucociliary clearance could also be affected by cilia length. Based on models of mucociliary
Externí odkaz:
https://doaj.org/article/9ae3ebb167754a9f99c554001f70d5d9
Autor:
Ronald G. Crystal, Yael Strulovici-Barel, Jason G. Mezey, Thomas L. Vincent, Robert J. Kaner, Abraham Sanders, Ben-Gary Harvey
Publikováno v:
The European respiratory journal. 47(6)
Smokers with normal spirometry/low DLCO are at higher risk of COPD versus those with normal DLCOhttp://ow.ly/4mQBwZ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fee8101ccb9561d12a2d6bbf65e7b3
https://pubmed.ncbi.nlm.nih.gov/27246082
https://pubmed.ncbi.nlm.nih.gov/27246082
Autor:
Yael Strulovici-Barel, Sreekumar G. Pillai, Ben-Gary Harvey, Michelle R. Staudt, Hans Bitter, Cynthia Gordon, Jay S. Fine, Christopher S. Stevenson, Robert J. Kaner, Ronald G. Crystal, Ann E. Tilley, Sudha Visvanathan, Anja Krause, Jason G. Mezey, Holly Hilton, Gerhard Wolff, Charleen Hollmann
Publikováno v:
Thorax. 71(12)
Introduction Increasing evidence links COPD pathogenesis with pulmonary capillary apoptosis. We previously demonstrated that plasma levels of circulating microparticles released from endothelial cells (EMPs) due to apoptosis are elevated in smokers w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8765b039050d119a486317ab1ecd33fa
https://pubmed.ncbi.nlm.nih.gov/27462120
https://pubmed.ncbi.nlm.nih.gov/27462120
Autor:
Bishnu P. De, Ben-Gary Harvey, Rui Wang, Ronald G. Crystal, Angeliki Kazeros, Holly Vanni, Timothy O'Connor, Barbara Ferris, Ralf-Harto Hübner, Brendan J. Carolan
Publikováno v:
Chest. 135:1197-1208
Smokers weigh less and have less body fat than nonsmokers. Increased body fat and weight gain are observed following smoking cessation. To assess a possible molecular mechanism underlying the inverse association between smoking and body weight, we hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17485cbfc4c700f342b821ee713d91ca
https://doi.org/10.1378/chest.08-1024
https://doi.org/10.1378/chest.08-1024
Overexpression of Apoptotic Cell Removal Receptor MERTK in Alveolar Macrophages of Cigarette Smokers
Autor:
Angeliki Kazeros, Brendan J. Carolan, Holly Vanni, Anja Krause, Ronald G. Crystal, Ben-Gary Harvey
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 39:747-757
Mononuclear phagocytes play an important role in the removal of apoptotic cells by expressing cell surface receptors that recognize and remove apoptotic cells. Based on the knowledge that cigarette smoking is associated with increased lung cell turno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b65d3fc46803355793c9681cbc10803
https://doi.org/10.1165/rcmb.2007-0306oc
https://doi.org/10.1165/rcmb.2007-0306oc
Autor:
Ronald G. Crystal, Jason G. Mezey, Yael Strulovici-Barel, Robert J. Kaner, Ben-Gary Harvey, Abraham Sanders, Thomas L. Vincent
Smokers are assessed for chronic obstructive pulmonary disease (COPD) using spirometry, with COPD defined by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) as airflow limitation that is not fully reversible with bronchodilators. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f46fb20f6d016b7831099298462323
https://europepmc.org/articles/PMC4752006/
https://europepmc.org/articles/PMC4752006/
