Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ben Verpaalen"'
Publikováno v:
Antiviral Research. 105:92-99
Statins are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors that are widely used for the treatment of hypercholesterolemia. Besides their cholesterol-lowering effect, statins have been reported to have antiviral activity against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355de2a2e202d37dd5c69961fa84a0d9
https://doi.org/10.1016/j.antiviral.2014.02.020
https://doi.org/10.1016/j.antiviral.2014.02.020
Publikováno v:
Dupont, D M, Bjerregaard, N, Verpaalen, B, Andreasen, P A & Jensen, J K 2016, ' Building a Molecular Trap for a Serine Protease from Aptamer and Peptide Modules ', Bioconjugate Chemistry, vol. 27, no. 4, pp. 918-926 . https://doi.org/10.1021/acs.bioconjchem.6b00007
In drug development, molecular intervention strategies are usually based on interference with a single protein function, such as enzyme activity or receptor binding. However, in many cases, protein drug targets are multifunctional, with several molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e34dabc132e1c2032b6cbaf7bb67103
https://pubmed.ncbi.nlm.nih.gov/26926041
https://pubmed.ncbi.nlm.nih.gov/26926041
Autor:
Dirk Daelemans, Els Scheers, Johan Neyts, Els Vanstreels, Leen Delang, Ben Verpaalen, Catherine M. Verfaillie, Mareike Grabner, Nicky Helsen
Publikováno v:
Biochemical pharmacology. 96(3)
A number of statins, the cholesterol-lowering drugs, inhibit the in vitro replication of hepatitis C virus (HCV). In HCV-infected patients, addition of statins to the earlier standard of care therapy (pegIFN-α and ribavirin) resulted in increased su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35728e2ed02df4f842f60648141b388
https://pubmed.ncbi.nlm.nih.gov/26070251
https://pubmed.ncbi.nlm.nih.gov/26070251