Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ben Usher"'
Autor:
Tom J. Arrowsmith, Xibing Xu, Shangze Xu, Ben Usher, Peter Stokes, Megan Guest, Agnieszka K. Bronowska, Pierre Genevaux, Tim R. Blower
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Nucleotidyltransferases (NTases) control diverse physiological processes, including RNA modification, DNA replication and repair, and antibiotic resistance. The Mycobacterium tuberculosis NTase toxin family, MenT, modifies tRNAs to block tra
Externí odkaz:
https://doaj.org/article/0b8cfa70586a40899ff0c0d5f6b0b175
Autor:
Xibing Xu, Ben Usher, Claude Gutierrez, Roland Barriot, Tom J. Arrowsmith, Xue Han, Peter Redder, Olivier Neyrolles, Tim R. Blower, Pierre Genevaux
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Mycobacterium tuberculosis, the bacterium responsible for human tuberculosis, has a genome encoding a remarkably high number of toxin-antitoxin systems of largely unknown function. We have recently shown that the M. tuberculosis genome encod
Externí odkaz:
https://doaj.org/article/192b7c0f9cc2492486b0eb24b655df5a
Publikováno v:
Biochemical Journal
Biochemical journal, 2020, Vol.477(12), pp.2401-2419 [Peer Reviewed Journal]
Biochemical journal, 2020, Vol.477(12), pp.2401-2419 [Peer Reviewed Journal]
Toxin-antitoxin systems play key roles in bacterial adaptation, including protection from antibiotic assault and infection by bacteriophages. The type IV toxin-antitoxin system AbiE encodes a DUF1814 nucleotidyltransferase-like toxin, and a two-domai
Autor:
Ben Usher, Yiming Cai
Publikováno v:
TheScienceBreaker.
Autor:
Tim R. Blower, Peter C. Fineran, Robert D. Fagerlund, Simon A. Jackson, Izaak N Beck, Nils Birkholz, Ben Usher
Publikováno v:
Journal of Structural Biology
Journal of Structural Biology, 2021, Vol.213(3), pp.107752 [Peer Reviewed Journal]
Journal of Structural Biology, 2021, Vol.213(3), pp.107752 [Peer Reviewed Journal]
Graphical abstract
Highlights • The crystal structure of the anti-CRISPR repressor Aca2 has been solved to 1.34 Å. • Aca2 contains a new dimerization domain for HTH transcriptional regulators. • Aca2-like regulators are found encoded in d
Highlights • The crystal structure of the anti-CRISPR repressor Aca2 has been solved to 1.34 Å. • Aca2 contains a new dimerization domain for HTH transcriptional regulators. • Aca2-like regulators are found encoded in d
Autor:
Yiming, Cai, Ben, Usher, Claude, Gutierrez, Anastasia, Tolcan, Moise, Mansour, Peter C, Fineran, Ciarán, Condon, Olivier, Neyrolles, Pierre, Genevaux, Tim R, Blower
Publikováno v:
Science Advances
The human pathogen Mycobacterium tuberculosis produces a toxin that can stall bacterial growth by blocking the activity of tRNAs.
Toxin-antitoxin systems are widespread stress-responsive elements, many of whose functions remain largely unknown.
Toxin-antitoxin systems are widespread stress-responsive elements, many of whose functions remain largely unknown.
Autor:
Tim R. Blower, Moise Mansour, Claude Gutierrez, Peter C. Fineran, Ben Usher, Yiming Cai, Anastasia Tolcan, Pierre Genevaux, Ciarán Condon, Olivier Neyrolles
Publikováno v:
Science Advances
Science Advances, American Association for the Advancement of Science (AAAS), 2020, 6 (31), pp.eabb6651. ⟨10.1126/sciadv.abb6651⟩
Science advances, 2020, Vol.6(31), pp.eabb6651 [Peer Reviewed Journal]
Science Advances, American Association for the Advancement of Science (AAAS), 2020, 6 (31), pp.eabb6651. ⟨10.1126/sciadv.abb6651⟩
Science advances, 2020, Vol.6(31), pp.eabb6651 [Peer Reviewed Journal]
International audience; Toxin-antitoxin systems are widespread stress-responsive elements, many of whose functions remain largely unknown. Here, we characterize the four DUF1814-family nucleotidyltransferase-like toxins (MenT1–4) encoded by the hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42313afb299dde54fbae4e3f2d47a9be
https://hal-cnrs.archives-ouvertes.fr/hal-03019025
https://hal-cnrs.archives-ouvertes.fr/hal-03019025