Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ben T Grys"'
Autor:
Oren Z Kraus, Ben T Grys, Jimmy Ba, Yolanda Chong, Brendan J Frey, Charles Boone, Brenda J Andrews
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 4, Pp 1-15 (2017)
Abstract Existing computational pipelines for quantitative analysis of high‐content microscopy data rely on traditional machine learning approaches that fail to accurately classify more than a single dataset without substantial tuning and training,
Externí odkaz:
https://doaj.org/article/7d17f04c8f62472f87fec588070afc4e
Autor:
Jinglin L. Xie, Longguang Qin, Zhengqiang Miao, Ben T. Grys, Jacinto De La Cruz Diaz, Kenneth Ting, Jonathan R. Krieger, Jiefei Tong, Kaeling Tan, Michelle D. Leach, Troy Ketela, Michael F. Moran, Damian J. Krysan, Charles Boone, Brenda J. Andrews, Anna Selmecki, Koon Ho Wong, Nicole Robbins, Leah E. Cowen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Cas5 is a transcriptional regulator of responses to cell wall stress in the fungal pathogen Candida albicans. Here, Xie et al. show that Cas5 also modulates cell cycle dynamics and responses to antifungal drugs.
Externí odkaz:
https://doaj.org/article/ffb813afe4d54f829962b3863b93dbc3
Publikováno v:
Methods Mol Biol
Confocal Microscopy ISBN: 9781071614013
Confocal Microscopy ISBN: 9781071614013
We describe a protocol for live-cell high-throughput (HTP) screening of yeast mutant strains carrying fluorescent protein markers for subcellular compartments of choice using automated confocal microscopy. This procedure, which combines HTP genetics
Autor:
Michael F. Moran, Longguang Qin, Troy Ketela, Koon Ho Wong, Kenneth Ting, Nicole Robbins, Michelle D. Leach, Damian J. Krysan, Jinglin L. Xie, Zhengqiang Miao, Ben T. Grys, Leah E. Cowen, Brenda J. Andrews, Kaeling Tan, Anna Selmecki, Jonathan R. Krieger, Jiefei Tong, Jacinto De La Cruz Diaz, Charles Boone
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
The capacity to coordinate environmental sensing with initiation of cellular responses underpins microbial survival and is crucial for virulence and stress responses in microbial pathogens. Here we define circuitry that enables the fungal pathogen Ca
Autor:
Oren Kraus, Dara S. Lo, Charles Boone, Quaid Morris, Ben T. Grys, Brenda J. Andrews, Nil Sahin
Publikováno v:
The Journal of Cell Biology
Grys et al. review computer vision and machine-learning methods that have been applied to phenotypic profiling of image-based data. Descriptions are provided for segmentation, feature extraction, selection, and dimensionality reduction, as well as cl