Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ben S. Morgan"'
Publikováno v:
Org. Biomol. Chem.. 8:539-545
The addition of 3,4-dimethoxybenzyl thiol 8, as a benzyl thiol surrogate, to racemic 4-hydroxycyclopent-2-enone 2 and 4-hydroxycyclohex-2-enone 15 gave the corresponding cis-adducts (+/-)-3-(3,4-dimethoxybenzylthio)-4-hydroxycyclopentanone 4b and (+/
Publikováno v:
Tetrahedron Letters. 47:5273-5276
Following the thio-conjugate addition of (±)-9, its enantiomers were extremely efficiently discriminated using Novozym 435®. The thio-differentiating unit may then be removed either under reductive conditions, using Raney nickel, or following an ox
Publikováno v:
Tetrahedron: Asymmetry. 17:355-362
A new route to ( R )-4-hydroxycyclohex-2-enone from cyclohexanedione monoketal (27% yield) commences with reaction of the ketal with nitrosobenzene catalysed by l -proline. 4-Hydroxycyclohex-2-enone and 4-hydroxycyclopent-2-enone react with thiols to
Publikováno v:
Organic Letters. 7:43-46
The facile double reduction of bicyclic aromatic sulfonamides was used to synthesize a variety of 2- and 3-aryl-substituted pyrrolidines and 2-phenylpiperidine. The method features a combined nitrogen protection and a traceless tether for the transpo
Publikováno v:
Tetrahedron: Asymmetry. 15:2807-2809
Novozyme 435® (Candida antarctica Lipase B) effects the kinetic resolution of both 3-benzylthia-4-hydroxycyclopentanone and its six-membered ring analogue, providing a novel route to both enantiomers of 4-benzylthiacyclopent-2-enone and the two enan