Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ben P. Williams"'
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-21 (2023)
Abstract Background In several eukaryotes, DNA methylation occurs within the coding regions of many genes, termed gene body methylation (GbM). Whereas the role of DNA methylation on the silencing of transposons and repetitive DNA is well understood,
Externí odkaz:
https://doaj.org/article/3827d47d37a74d05a3cebdf11bee01b6
Autor:
Ben P. Williams, Mary Gehring
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
DNA methylation patterns are inherited over many generations in plants. Here, Williams and Gehring show that the 5-methylcytosine DNA glycosylase ROS1 functions as part of a methylation-sensitive circuit that ensures long-term epigenetic fidelity in
Externí odkaz:
https://doaj.org/article/ad6d7eb45f434846a9749db5a392c023
Autor:
David Hymel, Felix Wojcik, Kim S. Halskov, Wouter F. J. Hogendorf, Sydnee C. Wong, Ben M. Williams, Asmus R. Mortensen, Nick Cox, Ayesha Misquith, Nanna B. Holländer, Finn Matthiesen, Suneet Mehrotra, Michael R. Harris
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract C-terminal α-amidated peptides are attractive therapeutic targets, but preparative methods to access amidated pharmaceuticals are limited both on lab and manufacturing-scale. Here we report a straightforward and scalable approach to the C-t
Externí odkaz:
https://doaj.org/article/9979539e39a44b69b33db07562ed5803
Autor:
Lauren E. Hatcher, Mark R. Warren, Jonathan M. Skelton, Anuradha R. Pallipurath, Lucy K. Saunders, David R. Allan, Paul Hathaway, Giulio Crevatin, David Omar, Ben H. Williams, Ben A. Coulson, Chick C. Wilson, Paul R. Raithby
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-9 (2022)
Time-resolved single-crystal X-ray diffraction experiments largely focus on timescales shorter than microseconds, whereby slower population dynamics are missed. Here, the authors resolve the 3D structures of photoexcited solid-state species with mill
Externí odkaz:
https://doaj.org/article/cab75134082c4ebdb2b9ffb4fc2685a6
Publikováno v:
The Plant Cell. 34:1189-1206
Cytosine methylation is a reversible epigenetic modification of DNA. In plants, removal of cytosine methylation is accomplished by the four members of the DEMETER (DME) family of 5-methylcytosine DNA glycosylases, named DME, DEMETER-LIKE2 (DML2), DML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::342d3e4f5bd2258480f7dce06e06ed30
https://doi.org/10.1093/plcell/koab319
https://doi.org/10.1093/plcell/koab319
BackgroundIn diverse eukaryotes, DNA methylation is deposited within the coding regions of many genes, termed gene body methylation (GbM). Whereas the role of DNA methylation on the silencing of transposons and repetitive DNA is well understood, gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91f51636573d3cf99fd59589e6ec4b70
https://doi.org/10.1101/2022.12.02.518885
https://doi.org/10.1101/2022.12.02.518885
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005142 (2015)
Genomes must balance active suppression of transposable elements (TEs) with the need to maintain gene expression. In Arabidopsis, euchromatic TEs are targeted by RNA-directed DNA methylation (RdDM). Conversely, active DNA demethylation prevents accum
Externí odkaz:
https://doaj.org/article/332b9bf7d00f43bdb13a03462a613a91
Publikováno v:
eLife, Vol 2 (2013)
C4 photosynthesis has independently evolved from the ancestral C3 pathway in at least 60 plant lineages, but, as with other complex traits, how it evolved is unclear. Here we show that the polyphyletic appearance of C4 photosynthesis is associated wi
Externí odkaz:
https://doaj.org/article/b8b350ad5ecb4402986550016eaca2c0
Autor:
Ivan, Reyna-Llorens, Steven J, Burgess, Gregory, Reeves, Pallavi, Singh, Sean R, Stevenson, Ben P, Williams, Susan, Stanley, Julian M, Hibberd
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(8)
We describe an ancient regulatory code that patterns the gene expression required for the efficient C4 pathway. This code is based on two regulatory elements located in exonic sequence that act cooperatively to repress transcription in specific cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1032f4a9a09c391446b64a46b0510f86
https://pubmed.ncbi.nlm.nih.gov/29432183
https://pubmed.ncbi.nlm.nih.gov/29432183
Publikováno v:
Trends in plant science. 17(4)
The C₄ pathway is found in 62 lineages of land plants. We assess evidence for parallel versus convergent evolution of C₄ photosynthesis from three approaches: (i) studies of specific genes and cis-elements controlling their expression; (ii) phylo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc3b252bb29dc9543949d31349704207
https://pubmed.ncbi.nlm.nih.gov/22326564
https://pubmed.ncbi.nlm.nih.gov/22326564