Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ben P. Hung"'
Publikováno v:
Biomechanics and Modeling in Mechanobiology. 21:1117-1131
Publikováno v:
Biomechanics and modeling in mechanobiology. 21(4)
Recent reports of adverse health effects (e.g., capsular contracture, lymphoma) linked to the absence or presence of texture on soft-tissue implants (e.g., breast implants) suggest surface topography may have pathological impact(s). We propose that s
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107199 (2014)
The innate immune response following bone injury plays an important role in promoting cellular recruitment, revascularization, and other repair mechanisms. Tumor necrosis factor-α (TNF) is a prominent pro-inflammatory cytokine in this cascade, and h
Externí odkaz:
https://doaj.org/article/c591e1614d30494cb04ab523bb2e7366
Publikováno v:
Stem cells (Dayton, Ohio), vol 36, iss 9
Cell-based approaches for musculoskeletal tissue repair are limited by poor cell survival and engraftment. Short-term hypoxic preconditioning of mesenchymal stem cells (MSCs) can prolong cell viability in vivo, while the aggregation of MSCs into sphe
Autor:
Ben P. Hung, Juan R. Garcia, Miguel Dias, Warren L. Grayson, Ashley L. Farris, Amir H. Dorafshar, Ethan Nyberg
Publikováno v:
Annals of Biomedical Engineering. 45:45-57
The treatment of craniofacial defects can present many challenges due to the variety of tissue-specific requirements and the complexity of anatomical structures in that region. 3D-printing technologies provide clinicians, engineers and scientists wit
Autor:
Miguel Dias, Amir H. Dorafshar, Christina Holmes, Warren L. Grayson, Bilal A. Naved, Ethan Nyberg, Ben P. Hung, Jennifer H. Elisseeff
Publikováno v:
ACS Biomaterials Science & Engineering. 2:1806-1816
Tissue-engineered approaches to regenerate bone in the craniomaxillofacial region utilize biomaterial scaffolds to provide structural and biological cues to stem cells to stimulate osteogenic differentiation. Bioactive scaffolds are typically compris
Autor:
David E. Sahar, Jenna N. Harvestine, Mark L. Weiss, Ben P. Hung, Tomas Gonzalez-Fernandez, J. Kent Leach, Augustine M. Saiz
Publikováno v:
Biomaterials. 189
The maintenance and direction of stem cell lineage after implantation remains challenging for clinical translation. Aggregation and encapsulation into instructive biomaterials after preconditioning can bolster retention of differentiated phenotypes.
Publikováno v:
Journal of Biomedical Materials Research Part A. 101:3592-3598
There has been great interest in use of mesenchymal stem cell (MSC)-based therapies for cartilage repair. Most recently, treatments involving intra-articular injection of MSCs have shown great promise for cartilage repair and arthritis therapy, which
Autor:
Warren L. Grayson, Gerhard S. Mundinger, Philip S. Brazio, Josh Temple, Ben P. Hung, Erin Salter, Emile N. Brown, Eduardo D. Rodriguez
Publikováno v:
Cells Tissues Organs. 198:87-98
The translation of tissue engineering approaches to the clinic has been hampered by the inability to find suitable multipotent cell sources requiring minimal in vitro expansion. Enhanced bone marrow (eBM), which is obtained by reaming long bone medul
Autor:
Dejie Zhou, Stephen Browne-Bourne, Damian C. Genetos, Ben P. Hung, J. Kent Leach, Kaitlin C. Murphy, Jessica Yeung
Publikováno v:
Journal of the Royal Society, Interface, vol 14, iss 127
Spheroids formed of mesenchymal stem cells (MSCs) exhibit increased cell survival and trophic factor secretion compared with dissociated MSCs, making them therapeutically advantageous for cell therapy. Presently, there is no consensus for the mechani