Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Ben Nicholas"'
Autor:
Ben Nicholas, Hyun-Hee Lee, Jane Guo, Milenko Cicmil, Cornelia Blume, René De Waal Malefyt, Ratko Djukanović
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Asthmatics are more susceptible to viral infections than healthy individuals and are known to have impaired innate anti-viral defences. Influenza A virus causes significant morbidity and mortality in this population. Immuno-modulatory regulators (IMR
Externí odkaz:
https://doaj.org/article/56be0a81d60549fab7bf0480d2859b0b
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1009894 (2022)
CD8+ and CD4+ T cells provide cell-mediated cross-protection against multiple influenza strains by recognising epitopes bound as peptides to human leukocyte antigen (HLA) class I and -II molecules respectively. Two challenges in identifying the immun
Externí odkaz:
https://doaj.org/article/1bf3ece51b514d45a53b8912a1ff289d
Autor:
Grace E Cooper, Zoe C Pounce, Joshua C Wallington, Leidy Y Bastidas-Legarda, Ben Nicholas, Chiamaka Chidomere, Emily C Robinson, Kirstin Martin, Anna S Tocheva, Myron Christodoulides, Ratko Djukanovic, Tom M A Wilkinson, Karl J Staples
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0163889 (2016)
Macrophages are essential to maintaining lung homoeostasis and recent work has demonstrated that influenza-infected lung macrophages downregulate their expression of the scavenger receptor CD36. This receptor has also been shown to be involved in pha
Externí odkaz:
https://doaj.org/article/e639ce5ada424e8988e2486263a2fc68
Autor:
Karl J Staples, Ben Nicholas, Richard T McKendry, C Mirella Spalluto, Joshua C Wallington, Craig W Bragg, Emily C Robinson, Kirstin Martin, Ratko Djukanović, Tom M A Wilkinson
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121527 (2015)
Lung macrophages are an important defence against respiratory viral infection and recent work has demonstrated that influenza-induced macrophage PDL1 expression in the murine lung leads to rapid modulation of CD8+ T cell responses via the PD1 recepto
Externí odkaz:
https://doaj.org/article/7d746146d0234b05942328a759da58d1
Autor:
Ben Nicholas, Alistair Bailey, Katy J. McCann, Oliver Wood, Robert C. Walker, Robert Parker, Nicola Ternette, Tim Elliott, Tim J. Underwood, Peter Johnson, Paul Skipp
Publikováno v:
Immunology. 168:420-431
Oesophageal adenocarcinoma (OAC) has a relatively poor long-term survival and limited treatment options. Promising targets for immunotherapy are short peptide neoantigens containing tumour mutations, presented to cytotoxic T-cells by human leucocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64569e110e00231fc6bb451206bb910a
https://doi.org/10.1111/imm.13578
https://doi.org/10.1111/imm.13578
Autor:
Ben Nicholas, Alistair Bailey, Katy J McCann, Oliver Wood, Robert C Walker, Robert Parker, Nicola Ternette, Tim Elliott, Tim J Underwood, Peter Johnson, Paul Skipp
Esophageal adenocarcinoma (EAC) has a relatively poor long-term survival and limited treatment options. Promising targets for immunotherapy are short peptide neoantigens containing tumor mutations, presented to cytotoxic T-cells by human leukocyte an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61889e2f74dd53f04a3c37ba9e9624cb
https://doi.org/10.1101/2022.05.04.490567
https://doi.org/10.1101/2022.05.04.490567
Autor:
Ben Nicholas, Jane Guo, Hyun‐Hee Lee, Alistair Bailey, Rene de Waal Malefyt, Milenko Cicmil, Ratko Djukanovic
Asthma is a disease of complex origin and multiple pathologies. There are currently very few biomarkers of proven utility in its diagnosis, management or response to treatment. Recent studies have identified multiple asthma phenotypes following biofl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3246b6669865a593b04184854f476f
https://doi.org/10.1101/2022.01.12.22268892
https://doi.org/10.1101/2022.01.12.22268892
Publikováno v:
Smart Innovation, Systems and Technologies ISBN: 9789811636745
Medical image processing has a very important role in medical diagnosis where a doctor can compare the scanned image of his patient with a heap of images and find the result of the image that matches with it. With the help of feature descriptors, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e1b2eb3c33cba58bd5d457f9d5a5976
https://doi.org/10.1007/978-981-16-3675-2_25
https://doi.org/10.1007/978-981-16-3675-2_25
Akademický článek
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Autor:
Kian Fan Chung, Ben Nicholas, Norbert Krug, Peter J. Sterk, Ian M. Adcock, James P.R. Schofield, Ana R. Sousa, Thomas Sandström, Susan J. Wilson, Fabio Strazzeri, René Lutter, Massimo Caruso, Peter H. Howarth, Aruna T. Bansal, Jeanne-Marie Perotin-Collard, Stephen J. Fowler, Per Bakke, Ildiko Horvath, Diane Lefaudeux, John H. Riley, Paolo Montuschi, Joost Brandsma, Kai Sun, Bertrand De Meulder, Dominick E. Shaw, Paul Skipp, Yike Guo, Sven-Erik Dahlén, Charles Auffray, Xian Yang, Ioannis Pandis, Julie Corfield, Anthony Rowe, Jonathan Ward, Ratko Djukanovic, Marek Sanak
Background: Blood eosinophil counts ≥0.3x109/L are used to define Type-2, eosinophilic asthma. However, differential responses to T2 biologics of patients with eosinophilic asthma suggests that thi ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d25b29f084e65a900cb07e9469cd3f8
http://hdl.handle.net/10044/1/76949
http://hdl.handle.net/10044/1/76949