Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ben McKeever-Abbas"'
Autor:
Robert L. Woodward, Ben McKeever-Abbas, Richard Hart, Nicholas I. Pedge, Gareth P. Howell, Adam Herring
Publikováno v:
Organic Process Research & Development. 19:537-542
Process analytical technology (PAT) was used to probe, monitor, and control the formation of process impurities during the synthesis of a pharmaceutical intermediate at 600 kg input scale. An accurate determination of end of reaction (EoR) was vital
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04cd9502635cf2a87d4ae551765a28cf
https://doi.org/10.1021/acs.oprd.5b00008
https://doi.org/10.1021/acs.oprd.5b00008
Publikováno v:
ChemInform. 47
Commercially available iron(III) and copper(I) complexes catalyzed multicomponent cycloaddition reactions between diazo compounds, pyridines, and electrophilic alkenes to give alkaloid-inspired tetrahydroindolizidines in high yield with high diastere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f389e1481fb199765132f84e5f1ec062
https://doi.org/10.1002/chin.201635054
https://doi.org/10.1002/chin.201635054
Autor:
Mark Drew, J. Gair Ford, Alistair Boyd, Kevin William Leslie, Ji-long Jiang, Bob Suchozak, Stephen Gottschling, Gwydion Churchill, Sarah Lyons, Paula Tomlin, Josephine Lo, Murray Watson AstraZeneca Cuthbert, Matthew Ball, Michael David Golden, Andrew Stark, Lianne Frodsham, Ben McKeever-Abbas, Mark Richard Fielding, Abraham Hajar
Publikováno v:
Organic Process Research & Development. 16:741-747
The intramolecular Diels–Alder reaction provides a useful synthetic methodology to build biologically active and synthetically useful isoindolone ring systems. An application of this methodology, p...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c528a5c1ed16c94382062fccf77b5bac
https://doi.org/10.1021/op300002f
https://doi.org/10.1021/op300002f
Autor:
Ben McKeever-Abbas, Sarah Murrison, Adam Nelson, Sushil K. Maurya, Stuart L. Warriner, Christian Einzinger
Publikováno v:
European Journal of Organic Chemistry. 2011:2354-2359
A synthetic approach to skeletally diverse alkaloid-like compounds, involving two consecutive three-component reactions, was developed. First, reaction between a range of secondary amines, carbonyl compounds and triazines yielded cyclic imines. Cruci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1a51d080bae8e88be0691370c1487f1
https://doi.org/10.1002/ejoc.201100116
https://doi.org/10.1002/ejoc.201100116
Autor:
Adam Nelson, James Titchmarsh, Ben McKeever-Abbas, Sarah Murrison, Stuart L. Warriner, Stephen Bartlett, Christian Einzinger, David R. Glowacki
Publikováno v:
Chemistry - A European Journal. 15:2185-2189
Look, no ortho substituents! A series of polycycles were prepared by using a three-component Joullié-Ugi reaction. The rate of rotation about the bond between a highly hindered bridgehead and a phenyl ring with no ortho substituents was measured, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d4de6e2a2153f75998c035b08d6843
https://doi.org/10.1002/chem.200802127
https://doi.org/10.1002/chem.200802127
Publikováno v:
Angewandte Chemie (International ed. in English). 55(19)
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Commercially available iron(III) and copper(I) complexes catalyzed multicomponent cycloaddition reactions between diazo compounds, pyridines, and electrophilic alkenes to give alkaloid-inspired tetr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa15b8873368930c2e089b5d74839fe
https://pubmed.ncbi.nlm.nih.gov/27059910
https://pubmed.ncbi.nlm.nih.gov/27059910
Autor:
Richard A. Castledine, Maliha Uroos, James Dowden, Jonathan Day, Ben McKeever-Abbas, William Lewis
Publikováno v:
ChemInform. 45
Cycloaddition reactions between pyridinium ylides and 3-alkenyl oxindoles (I) proceed in high yields and with good regio- and diastereoselectivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01f69f7b909369b695f9d6fd838fbab7
https://doi.org/10.1002/chin.201404158
https://doi.org/10.1002/chin.201404158
Publikováno v:
Organic Letters. 10:2589-2591
The first examples of heterocycle synthesis by iminophosphorane formation/intramolecular aza-Wittig cyclizations that are catalytic in the organophosphorus component are reported. The reaction has been demonstrated in the synthesis of both azine (phe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060901b75e2ed9d101b69c4819cd6240
https://doi.org/10.1021/ol800921n
https://doi.org/10.1021/ol800921n
Autor:
William Lewis, Jonathan Day, Richard A. Castledine, James Dowden, Maliha Uroos, Ben McKeever-Abbas
Cycloaddition reactions between pyridinium ylides and 3-alkenyl oxindoles that proceed in high yield and with very good regio- and diastereoselectivity are reported. The resulting cycloadducts have the same stereochemistry of biologically active oxin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba19250af40e205e228e858cd5e257d1
https://nottingham-repository.worktribe.com/file/717062/1/Line_102_Alkaloid_inspired_spirocyclic.pdf
https://nottingham-repository.worktribe.com/file/717062/1/Line_102_Alkaloid_inspired_spirocyclic.pdf
Publikováno v:
ChemInform. 39
The first examples of heterocycle synthesis by iminophosphorane formation/intramolecular aza-Wittig cyclizations that are catalytic in the organophosphorus component are reported. The reaction has been demonstrated in the synthesis of both azine (phe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5018cf5b5895d191f199243c4d3261ed
https://doi.org/10.1002/chin.200845135
https://doi.org/10.1002/chin.200845135