Exceptional Response to Trastuzumab in a Heavily Pretreated Patient With ERBB3-Mutated Metastatic Breast Cancer

Autor: Annette Kolodzie, Jamie M. Keck, Zahi Mitri, Janice Patterson, Ben Kong, Christopher L. Corless, Brett Johnson, Marilyne Labrie, Gordon B. Mills, Alexander R. Guimaraes, Joe W. Gray, Regan Look, Carol Beadling, Raymond C. Bergan, Swapnil Parmar

Publikováno v: JCO Precis Oncol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1719cda13c73c587b488b8383c04a29c
https://doi.org/10.1200/po.20.00183

High response rate to PD-1 blockade in desmoplastic melanomas

Autor: Xiaoyan Wang, Georgina V. Long, Alistair J. Cochran, Pier Federico Gherardini, Suthee Rapisuwon, Michael A. Postow, Richard W. Joseph, Rodrigo Ramella Munhoz, Richard A. Scolyer, Jesse M. Zaretsky, Wen-Jen Hwu, Jeffrey A. Sosman, Alain Algazi, Douglas B. Johnson, Ben Kong, Jane L. Messina, Bartosz Chmielowski, Zeynep Eroglu, Elizabeth Liniker, Antoni Ribas, I. Peter Shintaku, Dae Won Kim, Matteo S. Carlino, Cody Wei, Siwen Hu-Lieskovan

Publikováno v: Nature, vol 553, iss 7688

Desmoplastic melanoma is a rare subtype of melanoma characterized by dense fibrous stroma, resistance to chemotherapy and a lack of actionable driver mutations, and is highly associated with ultraviolet light-induced DNA damage. We analysed sixty pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b175c501444d1ee21be230682077b7
https://hdl.handle.net/2108/312295

Abstract 4929: Leveraging multi-omics tumor boards for precision medicine in the OHSU SMMART Treatments Program

Autor: Jamie M. Keck, Swapnil Parmar, Ben Kong, Zahi Mitri, Christopher Corless, Annette Kolodzie, Allison Creason, Jeremy Goecks, Patrick Leyshock, Kiara Siex, Brett E. Johnson, Janice Patterson, Laura Heiser, Anastasiya Olson, Matt Viehdorfer, Georgia Mayfield, Jennifer Laverdure, Joe W. Gray, Gordon B. Mills, Raymond C. Bergan

Publikováno v: Cancer Research. 79:4929-4929

Comprehensive characterization of an individual’s cancer using multi-omic analyses and an expanding list of targeted therapies is providing an opportunity to uncover therapeutic vulnerabilities and rationally target multiple driving alterations in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f4981550a8bbaf65b68351cfa5bc324
https://doi.org/10.1158/1538-7445.am2019-4929

Analysis of mutational burden and adaptive immune response in desmoplastic melanomas treated with PD-1/L1 inhibitors

Autor: Rodrigo Ramella Munhoz, Wen-Jen Hwu, Siwen Hu-Lieskovan, Bartosz Chmielowski, Antoni Ribas, Alain Algazi, Douglas B. Johnson, Richard A. Scolyer, Michael A. Postow, Richard W. Joseph, Jesse M. Zaretsky, Suthee Rapisuwon, Ben Kong, Elizabeth Liniker, Georgina V. Long, Matteo S. Carlino, Zeynep Eroglu, Jeffrey A. Sosman, Dae Won Kim

Publikováno v: Journal of Clinical Oncology. 35:9558-9558

9558 Background: Desmoplastic melanoma (DM) is a rare subtype of melanoma characterized by a dense fibrous stroma, resistance to chemotherapy and no actionable driver mutation for targeted therapy. We investigated the efficacy of PD-1/L1 inhibitors a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25314ce583cc196601a0b7d20359c4a7
https://doi.org/10.1200/jco.2017.35.15_suppl.9558

Contributors

Autor: Laura L. Adams, Meredith C.B. Adams, Abbas Al-Qamari, Michael L. Ault, Rajpreet Bal, Karsten Bartels, Jeanette Bauchat, Honorio T. Benzon, Hubert A. Benzon, Charles B. Berde, Patrick K. Birmingham, Ronald James Botelho, Jessica Boyette-Davis, Chad M. Brummett, Allen W. Burton, Asokumar Buvanendran, Alejandra Camacho-Soto, Kenneth D. Candido, James Celestin, Kiran Chekka, Brian A. Chung, Michael R. Clark, Daniel J. Clauw, Steven P. Cohen, Christopher M. Criscuolo, Matthew T. Crooks, Emily Davoodi, Miles Day, Oscar A. deLeon-Casasola, Sudhir Diwan, Patrick M. Dougherty, Beth Dove, Robert H. Dworkin, Robert R. Edwards, Neil Ellis, F. Kayser Enneking, Michael Erdek, Danielle Factor, F. Michael Ferrante, Scott M. Fishman, Steven A. Galati, Sugantha Ganapathy, Harold J. Gelfand, Aaron M. Gilson, Michael Gofeld, Heidi V. Goldstein, Karina Gritsenko, Anthony Guarino, Haroon Hameed, Richard E. Harris, Jennifer A. Haythornthwaite, Jason L. Hennes, Mark Holtsman, Michelle R. Hoot, Eric S. Hsu, Julie H.Y. Huang, Marc Alan Huntoon, Robert W. Hurley, Brian M. Ilfeld, Rasha S. Jabri, Jonathan D. Jerman, Rafael Justiz, Ben Kong, Robert M. Levy, John C. Liu, Spencer S. Liu, Gagan Mahajan, Khalid M. Malik, Edward R. Mariano, James J. Mathews, Danesh Mazloomdoost, Colin J.L. McCartney, Terrence McNamara, Michael M. Minieka, William M. Mitchell, Robert E. Molloy, John D. Moore, Kenji Muro, Jamie D. Murphy, Antoun Nader, Allan Nanney, Samer Narouze, Takashi Nishida, Judith A. Paice, Marco R. Perez-Toro, Anahi Perlas, Jason E. Pope, Heidi Prather, Joel M. Press, Rohit Rahangdale, Srinivasa N. Raja, Shubha V.Y. Raju, James P. Rathmell, Ben A. Rich, W. Evan Rivers, Meghan Rodes, Joshua M. Rosenow, Lucas Rosiere, Jack M. Rozental, Eric J. Russell, Francis V. Salinas, Kenneth E. Schmader, Mehul P. Sekhadia, Ravi Shah, Hariharan Shankar, Samir Sheth, B. Todd Sitzman, Howard S. Smith, Gwendolyn Sowa, Eric M. Spitzer, Steven P. Stanos, Santhanam Suresh, Luminita Tureanu, Murugusundaram Veeramani, Charles F. von Gunten, David R. Walega, Matthew T. Walker, Ajay D. Wasan, Lynn R. Webster, Stephen T. Wegener, Debra K. Weiner, Bryan S. Williams, Kayode Williams, Barth L. Wilsey, Jessica Wolfman, Cynthia A. Wong, Christopher L. Wu, Jacques T. Ya Deau

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74748293914be51ada167d0e1757da8e
https://doi.org/10.1016/b978-1-4377-2242-0.00004-3