Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Ben Hitchinson"'
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Akademický článek
NMR resonance assignment and structure prediction of the C-terminal domain of the microtubule end-binding protein 3.
Autor: Hazem Abdelkarim, Ben Hitchinson, Xinyan Qu, Avik Banerjee, Yulia A Komarova, Vadim Gaponenko
Publikováno v: PLoS ONE, Vol 15, Iss 5, p e0232338 (2020)
End-binding proteins (EBs) associate with the growing microtubule plus ends to regulate microtubule dynamics as well as the interaction with intracellular structures. EB3 contributes to pathological vascular leakage through interacting with the inosi
Externí odkaz: https://doaj.org/article/6cdc06bbf99c4023ae76cb1bfd48398e
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3
Vemurafenib Inhibits Active PTK6 in PTEN-null Prostate Tumor Cells
Autor: Milica B. Gilic, Ben Hitchinson, Angela L. Tyner, Vadim Gaponenko, Wenjun Bie, Darren J. Wozniak
Publikováno v: Molecular Cancer Therapeutics. 18:937-946
Protein tyrosine kinase 6 (PTK6, also called BRK) is overexpressed and activated in human prostate cancer. Loss of the tumor suppressor PTEN, a frequent event in prostate cancer, leads to PTK6 activation at the plasma membrane and its oncogenic signa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::70e96a671f82969bb41f01727af8c4d8
https://doi.org/10.1158/1535-7163.mct-18-0862
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6
Honokiol is a FOXM1 antagonist
Autor: Andrei L. Gartel, Binal N. Shah, Marianna Halasi, Renáta Váraljai, Irum Khan, Jack L. Arbiser, Ben Hitchinson, Vadim Gaponenko, Elizaveta V. Benevolenskaya
Publikováno v: Cell Death and Disease, Vol 9, Iss 2, Pp 1-8 (2018)
Cell Death & Disease
Honokiol is a natural product and an emerging drug for a wide variety of malignancies, including hematopoietic malignancies, sarcomas, and common epithelial tumors. The broad range of activity of honokiol against numerous malignancies with diverse ge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20e28c28da1514eb53998b0554baee6
http://link.springer.com/article/10.1038/s41419-017-0156-7
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7
Advances in NMR Methods to Identify Allosteric Sites and Allosteric Ligands
Autor: Hazem, Abdelkarim, Ben, Hitchinson, Avik, Banerjee, Vadim, Gaponenko
Publikováno v: Advances in experimental medicine and biology. 1163
NMR allows assessment of protein structure in solution. Unlike conventional X-ray crystallography that provides snapshots of protein conformations, all conformational states are simultaneously accessible to analysis by NMR. This is a significant adva
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7a392304234b60701a20b7670124eb39
https://pubmed.ncbi.nlm.nih.gov/31707704
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10
Advances in NMR Methods to Identify Allosteric Sites and Allosteric Ligands
Autor: Hazem Abdelkarim, Avik Banerjee, Ben Hitchinson, Vadim Gaponenko
Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9789811387180
NMR allows assessment of protein structure in solution. Unlike conventional X-ray crystallography that provides snapshots of protein conformations, all conformational states are simultaneously accessible to analysis by NMR. This is a significant adva
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21a0be944feaa81b5f1190342e9ae6e9
https://doi.org/10.1007/978-981-13-8719-7_8
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