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Autor:
Chong Wee Liew, Rohit N. Kulkarni, Masaru Akiyama, Shusheng Lu, Robert T. Kennedy, Jiang Hu, Ben Hambro, Rachael Martinez
Publikováno v:
Diabetes
Patients with type 2 diabetes (T2D) often exhibit hyperglucagonemia despite hyperglycemia, implicating defective α-cell function. Although endoplasmic reticulum (ER) stress has been suggested to underlie β-cell dysfunction in T2D, its role in α-ce