Výsledky vyhledávání - "Ben Greijdanus"

The influence of the dried blood spot drying time on the recoveries of six immunosuppressants

Autor: Rixt Botma, Ben Greijdanus, Daan J Touw, Jos G. W. Kosterink, Jan-Willem C. Alffenaar, Donald R. A. Uges, Remco A. Koster

Publikováno v: Journal of Applied Bioanalysis, Vol 1, Iss 4, Pp 116-122 (2015)

One of the main advantages of DBS sampling is that it allows the patient to sample at home and send the DBS sample to the laboratory by mail [1-4]. This sampling is considered to be patient friendly because it is less invasive and saves patients tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0736cdc586a44d0807b636863d7e382
https://doaj.org/article/24523814fe084706aec17b4c7bebbaa1

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Quantification of isoniazid, pyrazinamide and ethambutol in serum using liquid chromatography-tandem mass spectrometry

Autor: Ben Greijdanus, Marieke G G Sturkenboom, Erwin M Jongedijk, Wim Th. Kok, Henk van der Lijke, Jan-Willem C. Alffenaar, Donald R. A. Uges

Publikováno v: Journal of Applied Bioanalysis, Vol 1, Iss 3, Pp 89-98 (2015)
Journal of Applied Bioanalysis, 1(3), 89-98

Clinical studies on tuberculosis have shown a correlation between low drug exposure and treatment failure and acquired drug resistance. Objective was to develop a LC-MS/MS method for the quantification of isoniazid, pyrazinamide and ethambutol. Stabl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127a9926135b2edb4025f4f8ebc3ca3a
https://research.rug.nl/en/publications/9c80cdbe-16d0-4ebc-a636-89f435648a95

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Analysis of Remifentanil with Liquid Chromatography-Tandem Mass Spectrometry and an Extensive Stability Investigation in EDTA Whole Blood and Acidified EDTA Plasma

Autor: Remco A. Koster, Michel Struys, Jan-Willem C. Alffenaar, Hugo Vereecke, Daan J Touw, Ben Greijdanus

Publikováno v: Anesthesia and Analgesia, 120(6), 1235-1241. LIPPINCOTT WILLIAMS & WILKINS

BACKGROUND: Remifentanil is a mu-opioid receptor agonist that was developed as a synthetic opioid for use in anesthesia and intensive care medicine. Remifentanil is rapidly metabolized in both blood and tissues, which results in a very short duration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a96a100c248283f03bc57e4761ca232
https://doi.org/10.1213/ane.0000000000000643

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Optimisation of the sensitivity of an immunoassay analysis for tobramycin in serum

Autor: Marcel Hoppentocht, Onno W Akkeman, Jan-Willem C. Alffenaar, Albert-jan Voerman, Daan J Touw, Ben Greijdanus

Publikováno v: Journal of Applied Bioanalysis, 1(4), 123-127
Journal of Applied Bioanalysis, Vol 1, Iss 4, Pp 123-127 (2015)

Tobramycin is an aminoglycoside antimicrobial drug frequently used in anti-pseudomonal therapy in cystic fibrosis and non-cystic fibrosis bronchiectasis patients. Therapeutic drug monitoring is routinely performed to increase efficacy and reduce the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1bb059da4282bf068ed3029c09c4515
https://hdl.handle.net/11370/77ecba78-2aaf-4162-a40b-8576c6e09b1b

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Fast and Highly Selective LC-MS/MS Screening for THC and 16 Other Abused Drugs and Metabolites in Human Hair to Monitor Patients for Drug Abuse

Autor: Remco A. Koster, Ben Greijdanus, Donald R. A. Uges, Jan-Willem C. Alffenaar, Joanneke E. L. VanDerNagel

Publikováno v: Therapeutic Drug Monitoring, 36(2), 234-243. LIPPINCOTT WILLIAMS & WILKINS

Background:To facilitate the monitoring of drug abuse by patients, a method was developed and validated for the analysis of amphetamine, methamphetamine, 3,4-methylenedioxymethamphetamine, methylenedioxyamphetamine, methylenedioxyethylamphetamine, me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd1c389874c3f044aa9d58fd09f5562
https://doi.org/10.1097/ftd.0b013e3182a377e8

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Application of Sweat Patch Screening for 16 Drugs and Metabolites Using a Fast and Highly Selective LC-MS/MS Method

Autor: Donald R. A. Uges, Joanneke E. L. VanDerNagel, Ben Greijdanus, Remco A. Koster, Jan-Willem C. Alffenaar

Publikováno v: Therapeutic Drug Monitoring, 36(1), 35-45. LIPPINCOTT WILLIAMS & WILKINS

Background: To facilitate the monitoring of drug abuse by patients, a method was developed and validated for fast and highly selective screening for amphetamine, methamphetamine, 3,4-methylenedioxymethamphetamine, methylenedioxyamphetamine, methylene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd44bcbc7dee581bde1dd0a7b2d92c1
https://doi.org/10.1097/ftd.0b013e3182a04feb

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Fast LC-MS/MS analysis of tacrolimus, sirolimus, everolimus and cyclosporin A in dried blood spots and the influence of the hematocrit and immunosuppressant concentration on recovery

Autor: Remco A. Koster, Donald R. A. Uges, Jan-Willem C. Alffenaar, Ben Greijdanus

Publikováno v: Talanta, 115, 47-54. ELSEVIER SCIENCE BV

We developed a method for the analysis of four immunosuppressants in dried blood spot (DBS) samples to facilitate therapeutic drug monitoring for transplant patients outside the hospital. An 8 mm disc from the central part of the DBS was punched, ext

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7571605c66f92d016a3f621938344ed2
https://hdl.handle.net/11370/6d4c0b86-54d4-4c27-86e4-8d6c2a376a12

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Dried Blood Spot Analysis Suitable for Therapeutic Drug Monitoring of Voriconazole, Fluconazole, and Posaconazole

Autor: Ben Greijdanus, Karin M. Vermeulen, Jan-Willem C. Alffenaar, Kim C. M. van der Elst, Tjip S. van der Werf, Donald R. A. Uges, Jos G. W. Kosterink, Lambert F.R. Span, Kai van Hateren

Publikováno v: Antimicrobial Agents and Chemotherapy, 57(10), 4999-5004. AMER SOC MICROBIOLOGY

Invasive aspergillosis and candidemia are important causes of morbidity and mortality in immunocompromised and critically ill patients. The triazoles voriconazole, fluconazole, and posaconazole are widely used for the treatment and prophylaxis of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd331a7fa2932595afb71ff5578d106
https://hdl.handle.net/11370/aa9575ac-20c5-41db-a3f0-c2bee3014bcf

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Clinical Validation of the Analysis of Linezolid and Clarithromycin in Oral Fluid of Patients with Multidrug-Resistant Tuberculosis

Autor: Jos G. W. Kosterink, Donald R. A. Uges, R. van Altena, K. van Hateren, Jan-Willem C. Alffenaar, van der Tjipke Werf, Mathieu S. Bolhuis, Ben Greijdanus, de Wiel Lange

Publikováno v: Antimicrobial Agents and Chemotherapy, 57(8), 3676-3680. AMER SOC MICROBIOLOGY

Linezolid plays an increasingly important role in the treatment of multidrug-resistant tuberculosis (MDR-TB). However, patients should be carefully monitored due to time- and dose-dependent toxicity. Clarithromycin plays a more modest role. Therapeut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224b01f208d9389cd1350b8e9b1f8d2e
https://doi.org/10.1128/aac.00558-13

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Serum ibuprofen levels of extremely preterm infants treated prophylactically with oral ibuprofen to prevent patent ductus arteriosus

Autor: Nurdan Uras, Fuat Emre Canpolat, Serife Suna Oguz, Gozde Kanmaz, Ugur Dilmen, Omer Erdeve, Nahide Altug, Ben Greijdanus

Publikováno v: European Journal of Clinical Pharmacology, 69(5), 1075-1081. Springer Verlag

The aim of this study was to explore the effects of early oral ibuprofen administration on the incidence of hemodynamically significant patent ductus arteriosus (hsPDA) and define the association between serum ibuprofen levels and ductal closure.Pret

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b729f8e02b43e69fb997ddab2e4e43ca
https://doi.org/10.1007/s00228-012-1438-8

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