Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ben G.J.M. Bolscher"'
Autor:
Wilhelm Kaulfersch, P. M. Hilarius, Ben G.J.M. Bolscher, Ron S. Weening, Reinhard A. Seger, Dirk Roos, Arthur J. Verhoeven, Jeanette H. W. Leusen
Publikováno v:
The Journal of Experimental Medicine
Journal of experimental medicine, 180(6), 2329-2334. Rockefeller University Press
Journal of experimental medicine, 180(6), 2329-2334. Rockefeller University Press
Src homology 3 (SH3) domains have been suggested to play an important role in the assembly of the superoxide-forming nicotinamide adenine dinucleotide phosphate (NADPH) oxidase upon activation of phagocytes, which involves the association of membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff504551ff0716890540ff939b8f5a6b
http://europepmc.org/articles/PMC2191792
http://europepmc.org/articles/PMC2191792
Autor:
M de Boer, Stuart H. Orkin, Ben G.J.M. Bolscher, C. I. E. Smith, Anders Åhlin, Ron S. Weening, Mary C. Dinauer, Dirk Roos
Publikováno v:
Blood. 80:1553-1558
Chronic granulomatous disease (CGD) is characterized by the absence of a respiratory burst in activated phagocytes. Defects in at least four different genes lead to CGD. Patients with the X-linked form of CGD have mutations in the gene for the beta-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5c7fbdb446e4626d1b3af4d031dbf3d
https://doi.org/10.1182/blood.v80.6.1553.1553
https://doi.org/10.1182/blood.v80.6.1553.1553
Publikováno v:
Journal of Biological Chemistry. 265:15782-15787
Neutrophil NADPH:O2 oxidoreductase activity, essential in the killing of bacteria by neutrophils, can be elicited in a cell-free system that requires plasma membranes, cytosol and sodium dodecyl sulfate. In addition, GTP or its nonhydrolyzable analog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::602496dc0236f8142eed7721190af403
https://doi.org/10.1016/s0021-9258(18)55466-1
https://doi.org/10.1016/s0021-9258(18)55466-1
Publikováno v:
Journal of Biological Chemistry. 265:924-930
Phagocytic leukocytes contain an activatable NADPH:O2 oxidoreductase. Components of this enzyme system include cytochrome b558, and three soluble oxidase components (SOC I, SOC II, and SOC III) found in the cytosol of resting cells. Previously, we fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d8976f56301aed7eb2c594d249bb00a
https://doi.org/10.1016/s0021-9258(19)40138-5
https://doi.org/10.1016/s0021-9258(19)40138-5
Autor:
Dirk Roos, Ben G.J.M. Bolscher, R van Zwieten, Arthur J. Verhoeven, L. J. Van Pelt, Ron S. Weening
Publikováno v:
Journal of immunological methods, 191(2), 187-196. Elsevier
Intracellular oxidation of dihydrorhodamine 123 (DHR) to the fluorescent compound rhodamine 123 (Rho123) was used to detect the production of oxygen metabolites in activated neutrophils. Total leukocyte preparations can be used in this assay, which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c469fdee509619c42a63107ea279376d
https://pubmed.ncbi.nlm.nih.gov/8666838
https://pubmed.ncbi.nlm.nih.gov/8666838
Autor:
Jeanette H. W. Leusen, P. M. Hilarius, Ben G.J.M. Bolscher, Arthur J. Verhoeven, Dirk Roos, Kees Fluiter
Publikováno v:
Journal of biological chemistry, 270(19), 11216-11221. American Society for Biochemistry and Molecular Biology Inc.
Activation of the human NADPH oxidase requires the interaction of at least four cytosolic proteins and one membrane-bound heterodimeric protein. Src homology 3 (SH3) domains and their proline-rich counterstructures have been shown to play an importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e642d0bb25da7a7b024760fb4f83680
https://pubmed.ncbi.nlm.nih.gov/7744754
https://pubmed.ncbi.nlm.nih.gov/7744754
Publikováno v:
Mononuclear Phagocytes ISBN: 9789048141715
Phagocytic leukocytes (neutrophilic granulocytes, eosinophilic granulocytes, monocytes and macrophages) are effector cells in our defense against microbial pathogens. Phagocytes kill a variety of microorganisms by ingesting them and attacking them in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25c94522a1ad177aaddf9cf474b6a316
https://doi.org/10.1007/978-94-015-8070-0_32
https://doi.org/10.1007/978-94-015-8070-0_32
Autor:
Ron S. Weening, Dirk Roos, R van Zwieten, Louis Jan Meerhof, Arthur J. Verhoeven, Ben G.J.M. Bolscher, Jaap Keijer
Publikováno v:
Blood. 73:1686-1694
Monoclonal antibodies (MoAbs) were raised against cytochrome b558, a membrane-bound component of the NADPH:O2 oxidoreductase in human neutrophils. This cytochrome consists of a low-molecular-weight (low- mol-wt) subunit of 22 to 23 Kd, probably encod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89406c8dc8c8fc1783a57ff191163799
https://doi.org/10.1182/blood.v73.6.1686.1686
https://doi.org/10.1182/blood.v73.6.1686.1686
Publikováno v:
FEBS Letters. (1):269-273
The NADPH oxidase of human eosinophils, measured in the cell-free system, shows the same characteristics as the enzyme from human neutrophils. All proteins required for activity of the enzyme are expressed in eosinophils at a higher level than in neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0018f889104e61b9b03121ba51e1606d
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 784:189-191
Ascorbic acid (vitamin C) was found to stimulate the chlorinating activity of human myeloperoxidase (donor:hydrogen peroxide oxidoreductase, EC 1.11.1.7) 3-fold in vitro and to shift the pH optimum of the reaction to higher pH values. These effects a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb8b2e3b08ad286b61ebfa9e93244ca
https://doi.org/10.1016/0167-4838(84)90127-4
https://doi.org/10.1016/0167-4838(84)90127-4