Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ben G. Wen"'
Autor:
Andrew T Miller, Carol Dahlberg, Mark L Sandberg, Ben G Wen, Daniel R Beisner, John A H Hoerter, Albert Parker, Christian Schmedt, Monique Stinson, Jacqueline Avis, Cynthia Cienfuegos, Mark McPate, Pamela Tranter, Martin Gosling, Paul J Groot-Kormelink, Janet Dawson, Shifeng Pan, Shin-Shay Tian, H Martin Seidel, Michael P Cooke
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131071 (2015)
Emerging approaches to treat immune disorders target positive regulatory kinases downstream of antigen receptors with small molecule inhibitors. Here we provide evidence for an alternative approach in which inhibition of the negative regulatory inosi
Externí odkaz:
https://doaj.org/article/60911ac9821349a2a5779985bf95458d
Autor:
Advait Nagle, Ben G. Wen, Srinivasa P. S. Rao, Monique Stinson, Glenn C. Federe, Richard Glynne, Yin H. Lai, Ianne C. Rivera, Ansgar Brock, Michael Shapiro, Hazel X. Y. Koh, John D. Venable, Jaime Ballard, J. Robert Gillespie, Badry Bursulaya, Glen Spraggon, Xianzhong Liu, Mu-Yun Gao, Vince Yeh, Tove Tuntland, Fang Liang, S. Whitney Barnes, Todd Groessl, Shilpi Khare, Elmarie Myburgh, Agnes Biggart, Lauren C. Davis, Jocelyn Tan, Pranab Mishra, Frantisek Supek, Casey J. N. Mathison, Valentina Molteni, Jeremy C. Mottram, Frederick S. Buckner, John R. Walker
Publikováno v:
Nature
Chagas disease, leishmaniasis and sleeping sickness affect 20 million people worldwide and lead to more than 50,000 deaths annually1. The diseases are caused by infection with the kinetoplastid parasites Trypanosoma cruzi, Leishmania spp. and Trypano
Autor:
Vaughn V. Smider, Jan Grünewald, Richard A. Lerner, Diane M. Kubitz, Ben G. Wen, Peter G. Schultz, Frank Niessen, Meng Lin Tsao, Marc Nasoff, Wolfram Ruf, Liqun Dong, Roshan Perera
The ability to selectively induce a strong immune response against self-proteins, or increase the immunogenicity of specific epitopes in foreign antigens, would have a significant impact on the production of vaccines for cancer, protein-misfolding di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f0855f82ef83416ff0e737003af170
https://europepmc.org/articles/PMC2516224/
https://europepmc.org/articles/PMC2516224/
Publikováno v:
The FASEB Journal. 22
Autor:
Jacqueline Avis, Janet Dawson, Paul J. Groot-Kormelink, Albert E. Parker, Shifeng Pan, Mark L. Sandberg, Ben G. Wen, Andrew T. Miller, Cynthia Cienfuegos, H. Martin Seidel, Monique Stinson, Daniel R. Beisner, John A. H. Hoerter, Michael P. Cooke, Shin-Shay Tian, Pamela Tranter, Martin Gosling, Christian Schmedt, Mark McPate, Carol Dahlberg
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 6, p e0131071 (2015)
PLoS ONE, Vol 10, Iss 6, p e0131071 (2015)
Emerging approaches to treat immune disorders target positive regulatory kinases downstream of antigen receptors with small molecule inhibitors. Here we provide evidence for an alternative approach in which inhibition of the negative regulatory inosi
Autor:
Carol D. Katayama, Cornelis Murre, Ben G. Wen, Craig M. Walsh, Barbara L. Kee, Monica L. Friedrich, Gretchen Bain, Stephen M. Hedrick
Publikováno v:
International immunology. 17(11)
DAP kinases are a family of serine/threonine kinases known to regulate intrinsic apoptotic processes. DAP-related apoptotic kinase-2 (DRAK2) is highly expressed in lymphoid organs, with differential expression during thymocyte development. Low levels
Autor:
Ben G. Wen, Craig M. Walsh, Stephen M. Hedrick, Vishva M. Dixit, Karen O'Rourke, Arul M. Chinnaiyan
Publikováno v:
Immunity. 8(4)
FADD is a cytoplasmic adapter molecule that links the family of death receptors to the activation of caspases during apoptosis. We have produced transgenic mice expressing a dominantly interfering mutant of FADD, lacking the caspase-dimerizing death
Autor:
Monica L. Friedrich, Ben G. Wen, Gretchen Bain, Barbara L. Kee, Carol Katayama, Cornelis Murre, Stephen M. Hedrick, Craig M. Walsh
Publikováno v:
International Immunology; Nov2005, Vol. 17 Issue 11, p1379-1390, 12p
Publikováno v:
Immunity. (6):781-791
DRAK2 is a member of the death-associated protein (DAP)-like family of serine/threonine kinases. Members of this family induce apoptosis in various cell types. DRAK2, in particular, is specifically expressed in T cells and B cells, and it is differen