Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Ben G Marshall"'
Autor:
Mark G Jones, Orestis G Andriotis, James JW Roberts, Kerry Lunn, Victoria J Tear, Lucy Cao, Kjetil Ask, David E Smart, Alessandra Bonfanti, Peter Johnson, Aiman Alzetani, Franco Conforti, Regan Doherty, Chester Y Lai, Benjamin Johnson, Konstantinos N Bourdakos, Sophie V Fletcher, Ben G Marshall, Sanjay Jogai, Christopher J Brereton, Serena J Chee, Christian H Ottensmeier, Patricia Sime, Jack Gauldie, Martin Kolb, Sumeet Mahajan, Aurelie Fabre, Atul Bhaskar, Wolfgang Jarolimek, Luca Richeldi, Katherine MA O'Reilly, Phillip D Monk, Philipp J Thurner, Donna E Davies
Publikováno v:
eLife, Vol 7 (2018)
Matrix stiffening with downstream activation of mechanosensitive pathways is strongly implicated in progressive fibrosis; however, pathologic changes in extracellular matrix (ECM) that initiate mechano-homeostasis dysregulation are not defined in hum
Externí odkaz:
https://doaj.org/article/2541e80c33c2458ba21e589aed967251
Autor:
Liku B Tezera, Magdalena K Bielecka, Andrew Chancellor, Michaela T Reichmann, Basim Al Shammari, Patience Brace, Alex Batty, Annie Tocheva, Sanjay Jogai, Ben G Marshall, Marc Tebruegge, Suwan N Jayasinghe, Salah Mansour, Paul T Elkington
Publikováno v:
eLife, Vol 6 (2017)
Cell biology differs between traditional cell culture and 3-dimensional (3-D) systems, and is modulated by the extracellular matrix. Experimentation in 3-D presents challenges, especially with virulent pathogens. Mycobacterium tuberculosis (Mtb) kill
Externí odkaz:
https://doaj.org/article/e3dfc8abaaa44c1fa114aabbef91d0a5
Autor:
Zijian Xu, Elizabeth R. Davies, Liudi Yao, Yilu Zhou, Juanjuan Li, Aiman Alzetani, Ben G. Marshall, David Hancock, Tim Wallis, Julian Downward, Rob M. Ewing, Donna E. Davies, Mark G. Jones, Yihua Wang
Publikováno v:
Genes and Diseases, Vol 11, Iss 3, Pp 101065- (2024)
The factors that determine fibrosis progression or normal tissue repair are largely unknown. We previously demonstrated that autophagy inhibition-mediated epithelial–mesenchymal transition (EMT) in human alveolar epithelial type II (ATII) cells aug
Externí odkaz:
https://doaj.org/article/5746b35799c5474dafc24942f4b6652d
Autor:
Sandra Freitag-Wolf, Jonas C. Schupp, Björn C. Frye, Annegret Fischer, Raihanatul Anwar, Robert Kieszko, Violeta Mihailović-Vučinić, Janusz Milanowski, Dragana Jovanovic, Gernot Zissel, Elena Bargagli, Paola Rottoli, Dragos Bumbacea, René Jonkers, Ling-Pei Ho, Karoline I. Gaede, Anna Dubaniewicz, Ben G. Marshall, Andreas Günther, Martin Petrek, Michael P. Keane, Sigridur O. Haraldsdottir, Francesco Bonella, Christian Grah, Tatjana Peroš-Golubičić, Zamir Kadija, Stefan Pabst, Christian Grohé, János Strausz, Martina Safrankova, Ann Millar, Jiří Homolka, Wim A. Wuyts, Lisa G. Spencer, Michael Pfeifer, Dominique Valeyre, Venerino Poletti, Hubertus Wirtz, Antje Prasse, Stefan Schreiber, Astrid Dempfle, Joachim Müller-Quernheim
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionSarcoidosis is a highly variable disease in terms of organ involvement, type of onset and course. Associations of genetic polymorphisms with sarcoidosis phenotypes have been observed and suggest genetic signatures.MethodsAfter obtaining a
Externí odkaz:
https://doaj.org/article/ad511b3d40084d7293d0e9577c3c3078
Autor:
Aaron S. Karat, Annie S.K. Jones, Ibrahim Abubakar, Colin N.J. Campbell, Amy L. Clarke, Caroline S. Clarke, Marcia Darvell, Adam T. Hill, Robert Horne, Heinke Kunst, Mike Mandelbaum, Ben G. Marshall, Ceri McSparron, Ananna Rahman, Helen R. Stagg, Jacqui White, Marc C.I. Lipman, Karina Kielmann
Publikováno v:
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, Vol 23, Iss , Pp 100233- (2021)
Maintaining adherence to treatment for tuberculosis (TB) is essential if the disease is to be eliminated. As part of formative research to develop an intervention to improve adherence, we documented the lived experiences of adults receiving anti-TB t
Externí odkaz:
https://doaj.org/article/3e43d7a791c3462ca5eb46ea95ad79f4
Publikováno v:
Medical Science Educator. 33:459-464
Autor:
Diana J. Garay-Baquero, Cory H. White, Naomi F. Walker, Marc Tebruegge, Hannah F. Schiff, Cesar Ugarte-Gil, Stephen Morris-Jones, Ben G. Marshall, Antigoni Manousopoulou, John Adamson, Andres F. Vallejo, Magdalena K. Bielecka, Robert J. Wilkinson, Liku B. Tezera, Christopher H. Woelk, Spiros D. Garbis, Paul Elkington
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
BACKGROUND Tuberculosis (TB) kills more people than any other infection, and new diagnostic tests to identify active cases are required. We aimed to discover and verify novel markers for TB in nondepleted plasma.METHODS We applied an optimized quanti
Externí odkaz:
https://doaj.org/article/07efd161316b4f0ca6beceee411e2163
Autor:
Michael Eyres, Joseph A. Bell, Elizabeth R. Davies, Aurelie Fabre, Aiman Alzetani, Sanjay Jogai, Ben G. Marshall, David A. Johnston, Zijian Xu, Sophie V. Fletcher, Yihua Wang, Gayle Marshall, Donna E. Davies, Emily Offer, Mark G. Jones
A defining pathological feature of human lung fibrosis is localized tissue heterogeneity, which challenges the interpretation of transcriptomic studies that typically lose spatial information. Here we investigate spatial gene expression in diagnostic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c40bc01531a62cf3e61373c10a6403
https://eprints.soton.ac.uk/468826/
https://eprints.soton.ac.uk/468826/
Autor:
Stephen Poole, Mark Jones, Ben Welham, Lee Dexter, Tristan W Clark, Christopher McQuitty, Jose Horno, Emily Heiden, Tim Jm Wallis, Anna Freeman, Mark Watson, Tom Wilkinson, Hannah Burke, Ben G. Marshall, Alex Kong, Nathan J Brendish, Aishath Fazleen
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-9 (2021)
Respiratory Research
Respiratory Research
Background The long-term consequences of COVID-19 remain unclear. There is concern a proportion of patients will progress to develop pulmonary fibrosis. We aimed to assess the temporal change in CXR infiltrates in a cohort of patients following hospi
Autor:
Tim J.M. Wallis, Eyjólfur Gudmundsson, Katarina Pontoppidan, Nesrin Mogulkoc, Recep Savaş, Ömer Selim Unat, Katharine Vedwan, Sobana Battison, Fiona J. Thompson, Christopher J. Brereton, Ben G. Marshall, Sophie V. Fletcher, Luca Richeldi, Joseph Jacob, Mark G. Jones
[No Abstract Available]
NIHR Southampton Biomedical Research Centre; Wellcome Trust [209553/Z/17/Z]; NIHR UCLH Biomedical Research Centre, UK
J.M. Wallis receives a research fellowship from the NIHR Southampton Biomedical Research Centre. T
NIHR Southampton Biomedical Research Centre; Wellcome Trust [209553/Z/17/Z]; NIHR UCLH Biomedical Research Centre, UK
J.M. Wallis receives a research fellowship from the NIHR Southampton Biomedical Research Centre. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17eb2fd564f14bb39145b708c7891e57
https://eprints.soton.ac.uk/455106/
https://eprints.soton.ac.uk/455106/