Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ben D. Cox"'
Autor:
Abby S Primack, Jack F Cazet, Hannah Morris Little, Susanne Mühlbauer, Ben D Cox, Charles N David, Jeffrey A Farrell, Celina E Juliano
Publikováno v:
bioRxiv
The small freshwater cnidarian polypHydra vulgarisuses adult stem cells (interstitial stem cells) to continually replace neurons throughout its life. This feature, combined with the ability to image the entire nervous system (Badhiwala et al., 2021;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a251fa7b52ba8e9e638859e94e83977
https://doi.org/10.1101/2023.03.15.531610
https://doi.org/10.1101/2023.03.15.531610
Autor:
Ben D. Cox, Kenneth D. Poss, Valerie A. Tornini, Alessandro De Simone, Julia Wang, Anna Chao, Maya N. Evanitsky, Stefano Di Talia, Luke Hayden, Jianhong Ou
Publikováno v:
Nature
Regeneration is a complex chain of events that restores a tissue to its original size and shape. The tissue-wide coordination of cellular dynamics that is needed for proper morphogenesis is challenged by the large dimensions of regenerating body part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d19a83c67bee173ae9674c0a91c0cdb
http://europepmc.org/articles/PMC7864885
http://europepmc.org/articles/PMC7864885
Autor:
Chandan Shee, Ben D Cox, Franklin Gu, Elizabeth M Luengas, Mohan C Joshi, Li-Ya Chiu, David Magnan, Jennifer A Halliday, Ryan L Frisch, Janet L Gibson, Ralf Bernd Nehring, Huong G Do, Marcos Hernandez, Lei Li, Christophe Herman, PJ Hastings, David Bates, Reuben S Harris, Kyle M Miller, Susan M Rosenberg
Publikováno v:
eLife, Vol 2 (2013)
Spontaneous DNA breaks instigate genomic changes that fuel cancer and evolution, yet direct quantification of double-strand breaks (DSBs) has been limited. Predominant sources of spontaneous DSBs remain elusive. We report synthetic technology for qua
Externí odkaz:
https://doaj.org/article/59c34746bcbd42bfa4a8ac9f9ebfc171
Publikováno v:
Development
Regeneration has fascinated scientists since well before the 20th century revolutions in genetics and molecular biology. The field of regenerative biology has grown steadily over the past decade, incorporating advances in imaging, genomics and genome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a607912125424e452280f4ebdcf143
https://doi.org/10.1242/dev.181016
https://doi.org/10.1242/dev.181016
Autor:
Ben D. Cox, Kenneth D. Poss, Sumeet Pal Singh, Stefano Di Talia, Alessandro De Simone, Valerie A. Tornini
Publikováno v:
Current biology, 28 (24
Summary Osteoblasts are matrix-depositing cells that can divide and heal bone injuries. Their deep-tissue location and the slow progression of bone regeneration challenge attempts to capture osteoblast behaviors in live tissue at high spatiotemporal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ccb5e120e499c6d404a78cc0671dbc
https://europepmc.org/articles/PMC6298855/
https://europepmc.org/articles/PMC6298855/
Autor:
Thomas Clouaire, Jennifer S. Brodbelt, Poonam Agarwal, Li-Ya Chiu, François Aymard, Kyle M. Miller, Fade Gong, Mercedes Perez, Gaëlle Legube, Justin W.C. Leung, Ben D. Cox, Michael B. Cammarata
Publikováno v:
Genes & Development. 29:197-211
How chromatin shapes pathways that promote genome–epigenome integrity in response to DNA damage is an issue of crucial importance. We report that human bromodomain (BRD)-containing proteins, the primary “readers” of acetylated chromatin, are vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29152212ec89942309a1989b822054aa
https://doi.org/10.1101/gad.252189.114
https://doi.org/10.1101/gad.252189.114
Autor:
Valerie A. Tornini, Ben D. Cox, Valentina Cigliola, Yanchao Han, Kfir-Baruch Umansky, Kenneth D. Poss, Jingli Cao, Jianhong Ou, Eldad Tzahor, Amy L. Dickson, Oren Yifa, Wen-Yee Choi, Kelsey A. Oonk, Anzhi Chen
Publikováno v:
Developmental Cell. 48:853-863.e5
Summary Attaining proper organ size during development and regeneration hinges on the activity of mitogenic factors. Here, we performed a large-scale chemical screen in embryonic zebrafish to identify cardiomyocyte mitogens. Although commonly conside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf8c05660165598e964b4fdb89db9d8
https://doi.org/10.1016/j.devcel.2019.01.001
https://doi.org/10.1016/j.devcel.2019.01.001
Autor:
Michel Bagnat, Ben D. Cox, Kenneth D. Poss, Jingli Cao, Adam Navis, Ravi Karra, Matthew Gemberling, Amy L. Dickson
By contrast with mammals, adult zebrafish have a high capacity to regenerate damaged or lost myocardium through proliferation of spared cardiomyocytes. The epicardial sheet covering the heart is activated by injury and aids muscle regeneration throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895b915a8275d88581da9c881b908566
https://europepmc.org/articles/PMC4725347/
https://europepmc.org/articles/PMC4725347/
Autor:
Alberto Puliafito, Yi Fang, Kenneth D. Poss, Luca Primo, Ben D. Cox, Chen-Hui Chen, Stefano Di Talia
Publikováno v:
Developmental cell. 36(6)
Current fate mapping and imaging platforms are limited in their ability to capture dynamic behaviors of epithelial cells. To deconstruct regenerating adult epithelial tissue at single-cell resolution, we created a multicolor system, skinbow, that bar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807dce472391227a7e28d27de4a37ef2
https://pubmed.ncbi.nlm.nih.gov/27040485
https://pubmed.ncbi.nlm.nih.gov/27040485
Autor:
Ben D. Cox, Eric M. Small, Michael A. Trembley, Amanda H. Cox, Kenneth D. Poss, Jingli Cao, Amy L. Dickson, Stefano Di Talia, Jinhu Wang, Daniel P. Kiehart, Alessandro De Simone, Christopher P. Jackman, Nenad Bursac, Joseph J. Balowski
Publikováno v:
Developmental Cell. 42:600-615.e4
Mechanisms that control cell-cycle dynamics during tissue regeneration require elucidation. Here we find in zebrafish that regeneration of the epicardium, the mesothelial covering of the heart, is mediated by two phenotypically distinct epicardial ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a06a27ebf5923bf7109edf1cf614f474
https://doi.org/10.1016/j.devcel.2017.08.024
https://doi.org/10.1016/j.devcel.2017.08.024