Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ben D. Chen"'
Publikováno v:
American Journal of Biomedical Sciences. :47-55
The Protein kinase C (PKC) -associated signal pathway plays crucial roles in regulation of cell growth, differentiation and apoptosis. The present study focuses on conventional PKC (cPKC) expression and its regulation in primary cultures of bone marr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead7709ab03607d283c382f35cbda05f
https://doi.org/10.5099/aj090100047
https://doi.org/10.5099/aj090100047
Publikováno v:
Journal of Orthopaedic Research. 22:21-29
Activation of nuclear factor kappa B (NF-kappaB) signaling in response to cell stimulation by wear debris may be critical in the pathogenesis of aseptic loosening. Erythromycin (EM), a macrolide antibiotic, has been shown to effectively suppress some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6e9623e88b5b96171551e302a95498
https://doi.org/10.1016/s0736-0266(03)00130-x
https://doi.org/10.1016/s0736-0266(03)00130-x
Publikováno v:
Experimental Cell Research. 272:192-198
Induction of monocytic differentiation by bryostatin1 (bryo1) conferred on THP-1 leukemia cells the ability to resist Z-LLL-CHO-induced apoptosis. The mechanism of resistance developed during this process was investigated. Apoptosis resistance was as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c06451016d2d8a52dfc96931b068e3
https://doi.org/10.1006/excr.2001.5417
https://doi.org/10.1006/excr.2001.5417
Publikováno v:
Biochemical and Biophysical Research Communications. 286:401-405
To investigate whether apoptosis plays a role in traumatic brain injury (TBI), we examined the expression of Bcl-2 and Bax proteins and the release of mitochondrial cytochrome c in rat brains using Western blot analysis. Bcl-2 at the predicted 26 kDa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60622a00a77ca997ba17d4e19949f2d6
https://doi.org/10.1006/bbrc.2001.5396
https://doi.org/10.1006/bbrc.2001.5396
Autor:
Xiaohua Li, Ben D Chen
Histone acetylation plays an important role in the silencing and activation of genes involved in tumoregenesis. Trichostatin A, originally identified as an anti-fungal drug, is a potent inhibitor of histone deacetylase (HDAC) with potential anti-tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1548cd745db209702301a3a9d14ba42d
https://europepmc.org/articles/PMC2880493/
https://europepmc.org/articles/PMC2880493/
Autor:
Ben D. Chen, JuanJie Ren, Weiping Ren, Xin Peng, Dongzi Yu, Bin Wu, Lois Mayton, Paul H. Wooley
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 24(2)
Up to 20% of patients with total joint arthroplasty will develop radiographic evidence of aseptic loosening (AL), which most likely results from an inflammatory response to billions of wear debris shed from the implant. Our previous work has demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1e3a83c5339edb03bb958a9b0209d1
https://pubmed.ncbi.nlm.nih.gov/16435361
https://pubmed.ncbi.nlm.nih.gov/16435361
Publikováno v:
Frontiers in bioscience : a journal and virtual library. 9
Cyclooxygenase-2 (COX-2), an inducible prostaglandin G/H synthase, is overexpressed in pre-neoplastic tissues and several human cancers including colorectal cancer. Evidence linking COX-2 activity to carcinogenesis was derived from epidemiologic stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003fb23624b36231b3b2efe3ac88bd85
https://pubmed.ncbi.nlm.nih.gov/15353307
https://pubmed.ncbi.nlm.nih.gov/15353307
Autor:
Fred A. Valeriote, Balanehru Subramanian, Alexander Nakeff, Xiang Y. Liu, Ben D. Chen, Hong Lin
Publikováno v:
International journal of cancer. 97(1)
XK469 (NSC 697887) is a novel antitumor agent with broad activity against a variety of tumors. Previous studies suggest that XK469 is a topoisomerase lip poison with functional activity similar to that of 4'- (9-acridinylamino) methanesulfon-m-anisid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce39d96be869441c02a772f475864a4
https://pubmed.ncbi.nlm.nih.gov/11774253
https://pubmed.ncbi.nlm.nih.gov/11774253
Publikováno v:
Cancer chemotherapy and pharmacology. 49(4)
Purpose: XK469 (NSC 697887) is a novel antitumor agent with broad activity against a variety of tumors including drug-resistant tumors. Previous studies have indicated that XK469 is an antiproliferative agent with a low cytotoxic effect in human H116
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148b565f22e81a6e1a494d3f3aa85adc
https://pubmed.ncbi.nlm.nih.gov/11914906
https://pubmed.ncbi.nlm.nih.gov/11914906