Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Ben Crossett"'
Autor:
Desmarini Desmarini, Guizhen Liu, Henning Jessen, Bethany Bowring, Angela Connolly, Ben Crossett, Julianne Teresa Djordjevic
Publikováno v:
mBio, Vol 15, Iss 6 (2024)
ABSTRACT Inositol tris/tetrakis phosphate kinases (IP3-4K) in the human fungal priority pathogens, Cryptococcus neoformans (CnArg1) and Candida albicans (CaIpk2), convey numerous virulence functions, yet it is not known whether the IP3-4K catalytic a
Externí odkaz:
https://doaj.org/article/eafad44c526a4387bcd5b17913ea571e
Autor:
Christopher Hodgkins, Laura K. Buckton, Gregory J. Walker, Ben Crossett, Stuart J. Cordwell, Andrea R. Horvath, William D. Rawlinson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection has primarily been achieved using reverse transcriptase polymerase chain reaction (RT-PCR) for acute infection, and serology for prior infection. Assay with
Externí odkaz:
https://doaj.org/article/4369c81ba32a40c79646a52b480ddba0
Autor:
Yue Xuan, Nicholas W. Bateman, Sebastien Gallien, Sandra Goetze, Yue Zhou, Pedro Navarro, Mo Hu, Niyati Parikh, Brian L. Hood, Kelly A. Conrads, Christina Loosse, Reta Birhanu Kitata, Sander R. Piersma, Davide Chiasserini, Hongwen Zhu, Guixue Hou, Muhammad Tahir, Andrew Macklin, Amanda Khoo, Xiuxuan Sun, Ben Crossett, Albert Sickmann, Yu-Ju Chen, Connie R. Jimenez, Hu Zhou, Siqi Liu, Martin R. Larsen, Thomas Kislinger, Zhinan Chen, Benjamin L. Parker, Stuart J. Cordwell, Bernd Wollscheid, Thomas P. Conrads
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Distributed multi-omic digitization of clinical specimen across multiple sites is a prerequisite for turning molecular precision medicine into reality. Here, the authors show that coordinated proteotype data acquisition is feasible using standardized
Externí odkaz:
https://doaj.org/article/081c4a0800724593aa4ff7b531e0218f
Autor:
Matthew B. O’Rourke, Ben R. Roediger, Christopher J. Jolly, Ben Crossett, Matthew P. Padula, Phillip M. Hansbro
Publikováno v:
Proteomes, Vol 10, Iss 3, p 33 (2022)
(1) Background: MALDI imaging is a technique that still largely depends on time of flight (TOF)-based instrument such as the Bruker UltrafleXtreme. While capable of performing targeted MS/MS, these instruments are unable to perform fragmentation whil
Externí odkaz:
https://doaj.org/article/0fd37f180c4848a28c3bc620ac3b7088
Autor:
Han Chung Lee, Adam Carroll, Ben Crossett, Angela Connolly, Amani Batarseh, Michael A. Djordjevic
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Plant transmembrane proteins (TMPs) are essential for normal cellular homeostasis, nutrient exchange, and responses to environmental cues. Commonly used bottom–up proteomic approaches fail to identify a broad coverage of peptide fragments derived f
Externí odkaz:
https://doaj.org/article/bfcb14c870984b419575744f020a2ebc
Autor:
Desmarini Desmarini, Sophie Lev, David Furkert, Ben Crossett, Adolfo Saiardi, Keren Kaufman-Francis, Cecilia Li, Tania C. Sorrell, Lorna Wilkinson-White, Jacqueline Matthews, Dorothea Fiedler, Julianne Teresa Djordjevic
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT In the human-pathogenic fungus Cryptococcus neoformans, the inositol polyphosphate signaling pathway is critical for virulence. We recently demonstrated the key role of the inositol pyrophosphate IP7 (isomer 5-PP-IP5) in driving fungal virul
Externí odkaz:
https://doaj.org/article/a8826e64d46d4f19bb5e464319b44f8e
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 14, Iss 3, Pp 508-517 (2018)
The study of influenza virus evolution in humans has revealed a significant role of glycosylation profile alterations in the viral glycoproteins – hemagglutinin (HA) and neuraminidase (NA), in the emergence of both seasonal and pandemic strains. Vi
Externí odkaz:
https://doaj.org/article/90b14966fc594f8eaa7244dedc266b41
Autor:
Sophie Lev, Ben Crossett, So Young Cha, Desmarini Desmarini, Cecilia Li, Methee Chayakulkeeree, Christabel F. Wilson, P. R. Williamson, Tania C. Sorrell, Julianne T. Djordjevic
Publikováno v:
mBio, Vol 5, Iss 5 (2014)
ABSTRACT Cryptococcus neoformans strains isolated from patients with AIDS secrete acid phosphatase, but the identity and role of the enzyme(s) responsible have not been elucidated. By combining a one-dimensional electrophoresis step with mass spectro
Externí odkaz:
https://doaj.org/article/85d82a98a20445c1b18b76b2e03a0869
Autor:
David Van Ly, Alen Faiz, Christine Jenkins, Ben Crossett, Judith L Black, Brent McParland, Janette K Burgess, Brian G G Oliver
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56058 (2013)
Rhinovirus (RV) infections account for approximately two thirds of all virus-induced asthma exacerbations and often result in an impaired response to β2 agonist therapy. Using an in vitro model of RV infection, we investigated the mechanisms underly
Externí odkaz:
https://doaj.org/article/0b7931eb10c44f7d82117f181d73dadd
Autor:
Kaushal S Gandhi, Fiona C McKay, Eve Diefenbach, Ben Crossett, Stephen D Schibeci, Robert N Heard, Graeme J Stewart, David R Booth, Jonathan W Arthur
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10484 (2010)
Interferon beta (IFNbeta) is the most common immunomodulatory treatment for relapsing-remitting multiple sclerosis (RRMS). However, some patients fail to respond to treatment. In this study, we identified putative clinical response markers in the ser
Externí odkaz:
https://doaj.org/article/8c6ea329e8b54c66ae614ed5dc5195ca