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Non-Cognate Cytotoxic T Cells Can Be Retargeted Against CD20 Positive Tumour Cells Using [Fab' × MHC Class I/Peptide] Conjugates

Autor: Peter Johnson, Alison L. Tutt, Ruth R. French, Ben Cr King, Angela D. Hamblin, Philip Savage, Claude H.T. Chan, Martin J. Glennie

Publikováno v: Blood. 116:2838-2838

Abstract 2838 To circumvent cytotoxic T lymphocyte (CTL) tolerance of tumour-associated antigens, the concept of redirecting CTLs against non-cognate targets has developed. One way of doing this is to use bispecific antibodies comprising anti-CD3 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::888ebcbf03a05f0b5de9c4469e16f729
https://doi.org/10.1182/blood.v116.21.2838.2838

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