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Indwelling stents cause severe inflammation and fibrosis of the ureter via urothelial–mesenchymal transition

Autor: Alina Reicherz, Felipe Eltit, Kymora Scotland, Khaled Almutairi, Robert Bell, Bita Mojtahedzadeh, Michael Cox, Ben Chew, Dirk Lange

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)

Abstract To explore the pathways and mechanisms driving inflammation and fibrosis in stented ureters. In total, six healthy female pigs underwent cystoscopic unilateral ureteral stent insertion (6 Fr). After 14 days indwelling time, ureteral tissue w

Externí odkaz: https://doaj.org/article/d5b6d657633142e1ae47b6ca2e384c52

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Ureteral Obstruction Promotes Ureteral Inflammation and Fibrosis

Autor: Alina Reicherz, Felipe Eltit, Khaled Almutairi, Bita Mojtahedzadeh, Roman Herout, Ben Chew, Michael Cox, Dirk Lange

Publikováno v: European Urology Focus. 9:371-380

Hydronephrosis and renal impairment may persist even after relieving an obstruction, particularly in cases of chronic obstruction. Obstruction can cause fibrotic changes of the ureter, potentially contributing to long-term kidney damage.To characteri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c91ab99fe7620c2aebda4d02671daf10
https://doi.org/10.1016/j.euf.2022.09.014

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