Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ben Calverley"'
Autor:
Adam Pickard, Richa Garva, Antony Adamson, Ben Calverley, Anna Hoyle, Christina Hayward, David Spiller, Yinhui Lu, Nigel Hodson, Joe Swift, Brian Bigger, Karl Kadler
Vast numbers of elongated collagen fibrils are assembled in the extracellular matrix during development then persist unchanged throughout life to maintain tissue shape. How cells distinguish between the synthesis of new fibrils and elongation of exis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed57122ece2f99ee808d7fc94e4c5450
https://doi.org/10.21203/rs.3.rs-1336021/v1
https://doi.org/10.21203/rs.3.rs-1336021/v1
Autor:
Antony Adamson, Joan Chang, David F. Holmes, Qing-Jun Meng, Joe Swift, Oliver E. Jensen, Ching-Yan Chloé Yeung, Adam Pickard, Venkatesh Mallikarjun, Karl E. Kadler, Tom Shearer, Ben Calverley, Helena Raymond-Hayling, Yinhui Lu, Richa Garva
Publikováno v:
Chang, J, Garva, R, Pickard, A, Yeung, C Y C, Mallikarjun, V, Swift, J, Holmes, D, Calverley, B, Lu, Y, Adamson, A, Raymond-Hayling, H, Jensen, O, Shearer, T, Meng, Q-J & Kadler, K 2020, ' Circadian control of the secretory pathway maintains collagen homeostasis ', Nature Cell Biology, vol. 22, no. 1, pp. 74-86 . https://doi.org/10.1038/s41556-019-0441-z
Collagen is the most abundant secreted protein in vertebrates and persists throughout life without renewal. The permanency of collagen networks contrasts with both the continued synthesis of collagen throughout adulthood and the conventional transcri
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009840 (2021)
bioRxiv
PLoS Pathogens
bioRxiv
PLoS Pathogens
COVID-19 vaccines based on the Spike protein of SARS-CoV-2 have been developed that appear to be largely successful in stopping infection. However, therapeutics that can help manage the disease are still required until immunity has been achieved glob
The ability to quantitate a protein of interest temporally and spatially at subcellular resolution in living cells would generate new opportunities for research and drug discovery but remains a major technical challenge. Here, we describe dynamic pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47c77132e0f4cb0368b12d4f76e80e50
https://doi.org/10.1101/2020.05.17.099119
https://doi.org/10.1101/2020.05.17.099119
Autor:
Richa Garva, Adam Pickard, Peter Arvan, Ben Calverley, Karl E. Kadler, Joan Chang, Qing-Jun Meng, Nissrin Alachkar
Publikováno v:
Pickard, A, Chang, J, Alachkar, N, Calverley, B, Garva, R, Arvan, P, Meng, Q-J & Kadler, K 2019, ' Preservation of circadian rhythms by the protein folding chaperone, BiP ', The FASEB journal : official publication of the Federation of American Societies for Experimental Biology . https://doi.org/10.1096/fj.201802366RR
The FASEB Journal
The FASEB Journal
Dysregulation of collagen synthesis is associated with disease progression in cancer and fibrosis. Collagen synthesis is coordinated with the circadian clock, which in cancer cells is, curiously, deregulated by endoplasmic reticulum (ER) stress. We h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d455795d113f4e43bf42cf1f5a99d9cb
https://www.research.manchester.ac.uk/portal/en/publications/preservation-of-circadian-rhythms-by-the-protein-folding-chaperone-bip(38507d7f-c4ff-4284-b4d2-759d4f595e7e).html
https://www.research.manchester.ac.uk/portal/en/publications/preservation-of-circadian-rhythms-by-the-protein-folding-chaperone-bip(38507d7f-c4ff-4284-b4d2-759d4f595e7e).html
Autor:
Oliver E. Jensen, Venkatesh Mallikarjun, Joe Swift, Ching-Yan Chloé Yeung, Tom Shearer, Helena Raymond-Hayling, Yinhui Lu, Karl E. Kadler, Ben Calverley, David F. Holmes, Qing-Jun Meng, Antony Adamson, Adam Pickard, Richa Garva, Joan Chang
Collagen is the most abundant secreted protein in vertebrates that persists throughout life without renewal. The unchanging nature of collagen contrasts with observed continued collagen synthesis throughout adulthood and with conventional transcripti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34ccc2321c7ac5aa0e44460df281ba0